Impact of extracellular HIV-Tat on the regulation of EDF-1 levels in human endothelial cells

International Journal of Immunopathology and Pharmacology

Volumn 21, Issue 2, 2008, Pages 409-414

  Mariotti, M ^a   Bolognese, F ^a   Ferre S ^a   Leidi, M ^a   Maier, Jeanette A M ^a  

^a UNIVERSITY OF MILAN   (Italy)

Author keywords

Cells; EDF 1; Endothelial; HIV Tat

Indexed keywords

BENZYLOXYCARBONYLLEUCYLLEUCYLLEUCINAL; CALMODULIN; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYTOKINE; ENDOTHELIAL NITRIC OXIDE SYNTHASE; GENE PRODUCT; INTERLEUKIN 1BETA; LUCIFERASE; MESSENGER RNA; NITRIC OXIDE; PROTEIN EDF 1; PROTEIN KINASE C; PROTEINASE INHIBITOR; TRANSACTIVATOR PROTEIN;

ARTICLE; CELL ACTIVATION; CELL NUCLEUS; CONTROLLED STUDY; CYTOSOL; EDF 1 GENE; ENDOTHELIUM CELL; ENZYME ACTIVATION; ENZYME ACTIVITY; GENE; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; IN VITRO STUDY; MOLECULAR CLONING; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN ISOLATION; PROTEIN PROTEIN INTERACTION; PROTEIN TRANSPORT; RNA FINGERPRINTING; TRANSCRIPTION REGULATION;

EID: 47249141636     PISSN: 03946320     EISSN: None     Source Type: Journal    
DOI: 10.1177/039463200802100220     Document Type: Article

References (19)

1. Ensoli B, Buonaguro L, Barillari G, Fiorelli V, Gendelman R, Morgan RA, Wingfield P, Gallo RC. Release, uptake, and effects of extracellular human immunodeficiency virus type 1 Tat protein on cell growth and viral transactivation. J Virol 1993; 67: 277-81.
2. Hofman FM, Wright AD, Dohadwala MM, Wong-Staal F, Walker SM. Exogenous tat protein activates human endothelial cells. Blood 1993; 82:2774-9.
3. Subhash D, Puri RK, Kumar A, Duplan H, Masson JM, Aggarwal BB. Human Immunodeficiency Virus-1-Tat Protein Induces the Cell Surface Expression of Endothelial Leukocyte Adhesion Molecule-1, Vascular Cell Adhesion Molecule-1, and Intercellular Adhesion Molecule-1 in Human Endothelial Cells. Blood 1997; 90:1535-8.
4. Albini A, Soldi R, Giunciuglio D, Giraudo E, Benelli R, Primo L, Noonan D, Salio M, Camussi G, Rockl W, Bussolino F. The angiogenesis induced by HIV-1 tat protein is mediated by the Flk-1/KDR receptor on vascular endothelial cells. Nat Med 1996; 2:1371-7.
5. Liu K, Chi DS, Li C, Hall KH, Milhorn DM, Krishnaswamy G. HIV-1 Tat protein-induced VCAM-1 expression in human pulmonary artery endothelial cells and its signalling. Am J Physiol Lung Cell Mol Physiol 2005; 289:252-8.
6. Toschi E, Bacigalupo I, Strippoli R, Chiozzini C, Cereseto A, Falchi M, Nappi F, Sgadari C, Barillari G, Mainiero F, Ensoli B. HIV-1 Tat regulates endothelial cell cycle progression via activation of the Ras/ERK MAPK signaling pathway. Mol Biol Cell 2006; 7(4):1985-9.
7. Dragoni I, Mariotti M, Consalez GG, Soria MR, Maier JAM. EDF-1, a novel gene product down-regulated in human endothelial cell differentiation. J Biol Chem 1998; 273:31119-24.
8. De Benedictis L, Mariotti M, Dragoni I, Maier JAM. Cloning and characterization of murine EDF-1. Gene 2000; 275:299-305.
9. Mariotti M, De Benedictis L, Avon E, Maier JAM. Interaction between Endothelial Differentiation-related Factor-1 and Calmodulin in vitro and in vivo. J Biol Chem 2000; 275: 24047-51.
10. Ballabio E, Mariotti M, De Benedictis L, Maier JAM. The dual role of endothelial differentiation-related factor-1 in the cytosol and nucleus: modulation by protein kinase A. Cell Mol Life Sci 2004; 61:1069-75.
11. Bernardini D, Ballabio E, Mariotti M, Maier JAM. Differential expression of EDF-1 and endothelial nitric oxide synthase by proliferating, quiescent and senescent microvascular endothelial cells. Biochim Biophys Acta 2005; 1745:265-70.
12. Brendel C, Gelman L, Auwerx J. Multiprotein Bridging Factor-1 (MBF-1) is a cofactor for nuclear receptors that regulate lipid metabolism. Mol Endocrinol. 2002; 16:1367-9.
13. Bolognese F, Pitarque-Martì M, Lo Cicero V, Mantovani R, Maier JAM. Characterization of the human EDF-1 minimal promoter: involvement of NFY and Sp1 in the regulation of basal transcription. Gene 2006; 374:87-91.
14. Aresté C, Blackbourn DJ. HIV Tat-mediated transcriptional regulation of proteasome protein cleavage specificity. Biochem J 2006; 396:13-8.
15. Lee YW, Eum SY, Nath A, Toborek M. Estrogen-mediated protection against HIV Tat protein-induced inflammatory pathways in human vascular endothelial cells. Cardiovasc Res 2004; 63:139-43.
16. Toschi E, Bacigalupo I, Strippoli R, Chiozzini C, Cereseto A, Falchi M, Nappi F, Sgadari C, Barillari G, Mainiero F, Ensoli B. HIV-1 Tat regulates endothelial cell cycle progression via activation of the Ras/ERK MAPK signaling pathway. Mol Biol Cell 2006; 17:1985-89.
17. Marecki JC, Cota-Gomez A, Vaitaitis GM, Honda JR, Porntadavity S, St Clair DK, Flores SC. HIV-1 Tat regulates the SOD2 basal promoter by altering Sp1/Sp3 binding activity. Free Radic Biol Med 2004; 37:869-74.
18. Driscoll J, Goldberg AL. The proteasome (multicatalytic protease) is a component of the 1500-kDa proteolytic complex which degrades ubiquitin-conjugated proteins. J Biol Chem 1990; 265:4789-95.
19. Barillari G, Sgadari C, Palladino C, Gendelman R, Caputo A, Morris CB, Nair BC, Markham P, Nel A, Stürzl M, Ensoli B. Inflammatory cytokines synergize with the HIV-1 Tat protein to promote angiogenesis and Kaposi's sarcoma via induction of basic fibroblast growth factor and the alpha v beta 3 integrin. J. Immunol 1999; 163(4):1929-36.