Methotrexate: Advantages of subcutaneous administration;Methotrexat: Vorteile der subkutanen applikationsform

Zeitschrift fur Rheumatologie

Volumn 67, Issue 4, 2008, Pages 332-333

  Kruger K ^a  

^a Praxiszentrum St Bonifatius   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

DISEASE MODIFYING ANTIRHEUMATIC DRUG; GLUCOCORTICOID; METHOTREXATE;

ARTHRITIS; DRUG EFFICACY; DRUG SAFETY; HUMAN; LOW DRUG DOSE; MAJOR CLINICAL STUDY; NOTE; RHEUMATIC DISEASE; RHEUMATOID ARTHRITIS; RISK BENEFIT ANALYSIS; TREATMENT OUTCOME;

ADMINISTRATION, ORAL; ADULT; AGED; ANTIRHEUMATIC AGENTS; ARTHRITIS, RHEUMATOID; CLINICAL TRIALS AS TOPIC; DOUBLE-BLIND METHOD; FEMALE; HUMANS; INJECTIONS, SUBCUTANEOUS; MALE; METHOTREXATE; MIDDLE AGED; TREATMENT OUTCOME;

EID: 47249131647     PISSN: 03401855     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00393-008-0295-4     Document Type: Note

References (7)

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3. Hamilton RA, Kremer JM (1997) Why intramuscular methotrexate may be more efficacious than oral dosing in patients with rheumatoid arthritis. Br J Rheumatol 36: 86-90
4. Hoekstra M, Haagsma C, Neef C et al. (2004) Bioavailability of higher dose methotrexate comparing oral and subcutaneous administration in patients with rheumatoid arthritis. J Rheumatol 31: 645-648
5. Wegrzyn J, Adeleine P, Miossec P (2004) Better efficacy of methotrexate given by intramuscular injection than orally in patients with rheumatoid arthritis. Ann Rheum Dis 63: 1232-1234
6. Rozin A, Schapira D, Balbir-Gurman A et al. (2002) Relapse of rheumatoid arthritis after substitution of oral for parenteral administration of methotrexate. Ann Rheum Dis 61: 756-757
7. Bingham SJ, Buch MH, Lindsay S et al. (2003) Parenteral methotrexate should be given before biological therapy. Rheumatology 42: 1009-1010