Reduced meiotic recombination on the XY bivalent is correlated with an increased incidence of sex chromosome aneuploidy in men with non-obstructive azoospermia

Molecular Human Reproduction

Volumn 14, Issue 7, 2008, Pages 399-404

  Sun, F ^a,d   Mikhaail Philips, M ^a   Oliver Bonet, M ^a,e   Ko, E ^a   Rademaker, A ^b   Turek, P ^c   Martin, R H ^a  

^a UNIVERSITY OF CALGARY   (Canada)

^b NORTHWESTERN UNIVERSITY   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d UNIVERSITY OF SCIENCE AND TECHNOLOGY OF CHINA   (China)

^e UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

Author keywords

Azoospermia; ICSI; Meiotic recombination; Sperm aneuploidy; Synaptonemal complex

Indexed keywords

PROTEIN MLH1;

ADULT; ANEUPLOIDY; ARTICLE; AZOOSPERMIA; CHROMOSOME 21; CHROMOSOME 9; CHROMOSOME ANALYSIS; CHROMOSOME BIVALENT; CLINICAL ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; DISOMY; GENETIC RECOMBINATION; HUMAN; HUMAN CELL; MALE; MALE INFERTILITY; MALE STERILIZATION REVERSAL; MEIOSIS; MUTATION RATE; NONOBSTRUCTIVE AZOOSPERMIA; PACHYTENE; PRIORITY JOURNAL; SEMEN ANALYSIS; SEX CHROMOSOME; SPERMATOCYTE; SYNAPTONEMAL COMPLEX; X CHROMOSOME; Y CHROMOSOME;

ADULT; ANEUPLOIDY; AZOOSPERMIA; CHROMOSOMES, HUMAN, 21-22 AND Y; CHROMOSOMES, HUMAN, PAIR 9; CHROMOSOMES, HUMAN, X; CHROMOSOMES, HUMAN, Y; HUMANS; IN SITU HYBRIDIZATION; MALE; MEIOSIS; MIDDLE AGED; RECOMBINATION, GENETIC; SEX CHROMOSOME ABERRATIONS; SPERMATOCYTES; SYNAPTONEMAL COMPLEX; TESTIS;

EID: 47249123319     PISSN: 13609947     EISSN: 14602407     Source Type: Journal    
DOI: 10.1093/molehr/gan030     Document Type: Article

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