Selective targeting of pigmented retinal pigment epithelial (RPE) cells by a single pulsed laser irradiation: An in vitro study

Optics Express

Volumn 16, Issue 14, 2008, Pages 10518-10528

  Song, Q ^a   Risco, R ^b   Latina, M ^a   Berthiaume, F ^a   Nahmias, Y ^a   Yarmush, M L ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b UNIVERSIDAD DE SEVILLA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ALDEHYDES; CELLS; CYTOLOGY; IRRADIATION; LASER DAMAGE; OPHTHALMOLOGY;

CELLULAR DAMAGE; IN-VITRO; RADIANT EXPOSURE; RETINAL PIGMENT EPITHELIAL; RPE CELL; THERMAL COAGULATIONS;

PULSED LASERS;

MELANIN;

ARTICLE; BIOLOGICAL MODEL; BIOTECHNOLOGY; CELL CULTURE; CELL MEMBRANE; CELL SURVIVAL; CYTOLOGY; EQUIPMENT DESIGN; HUMAN; IN VITRO STUDY; LASER; METABOLISM; METHODOLOGY; OPTICS; PHAGOCYTOSIS; PIGMENT EPITHELIUM; RADIATION EXPOSURE; RETINA; SPECTROPHOTOMETRY;

BIOTECHNOLOGY; CELL MEMBRANE; CELL SURVIVAL; CELLS, CULTURED; EQUIPMENT DESIGN; HUMANS; LASERS; MELANINS; MODELS, BIOLOGICAL; OPTICS; PHAGOCYTOSIS; PIGMENT EPITHELIUM OF EYE; RETINA; SPECTROPHOTOMETRY;

EID: 47249097946     PISSN: None     EISSN: 10944087     Source Type: Journal    
DOI: 10.1364/OE.16.010518     Document Type: Article

References (17)

1. M. F. Marmor and T. J. Wolfensberger, The retinal pigment epithelium (Oxford University Press, New York, 1998).
2. R. R. Anderson and J. R. Parrish, "Selective photothermolysis: precise microsurgery by selective absorption of pulsed radiation," Science 220, 524-527 (1983).
3. V. P. Gabel, R. Birngruber, and F. Hillenkamp, Visible and near infrared light absorption in pigment epithelium and choroids. In International Congress Series No.450, XXIII concilium Ophthalmologicum, K. Shimizu, ed.Princeton, NJ: Excerpta Medica:1978:658-662). (Excerpta Medica, Princeton, NJ, 1978).
4. A. Leuenberger, "Treatment of diabetic retinopathy with photocoagulation," Mod. Probl. Ophthalmol. 10, 564-576 (1972).
5. J. Roider, F. Hillenkamp, T. J. Flotte, and R. Birngruber, "Microphotocoagulation: Selective effects of repetitive short laser pulses," Proc. Natl. Acad. Sci. U.S.A. 90, 8643-8647 (1993).
6. R. Brinkmann, N. Koop, M. Oezdemir, C. Alt, G. Schuele, C. P. Lin, and R. Birngruber, "Targeting of the retinal pigment epithelium (RPE) by means of a rapidly scanned continuous wave (CW) laser beam," Lasers Surg. Med. 32, 252-264 (2003).
7. K. C. Dunn, A. E. Aotaki-Keen, F. R. Putkey, and L. M. Hjelmeland, "ARPE-19, A human retinal pigment epitheial cell line with differentiated properties," Exp. Eye Res. 62, 155-169 (1996).
8. B. L. Seagle, E. M. Gasyna, W. F. Mieler, and J. R. J. Norris, "Photoprotection of human retinal pigment epithelium cells against blue light-induced apoptosis by melanin free radicals from Sepia officinalis," Proc. Natl. Acad. Sci. U. S. A. 103, 16644-16648 (2006).
9. M. Saham, K. U. Loeffler, P. Seifer, and M. Spitznas, "Effect of ultraviolet radiation on melanogenesis in four different types of cultured bovine ocular pigmented cells," Graefe's Arch. Clin. Exp. Ophthalmol. 239, 302-309 (2001).
10. A. E. Siegman, Defining and Measuring Laser Beam Parameters. In Laser Beam Characterization (Sociedad Espanola de Optica, Madrid, 1993).
11. S. Proulx, S. L. Guerin, and C. Salesse, "Effect of quiescence on integrin alpha5betal expression in human retinal pigment epithelium," Mol. Vis. 3, 473-481 (2003).
12. R. Birngruber, F. Hillenkamp, and V. P. Gabel, "Theoretical investigations of laser thermal retinal injury, " Health Phys. 48, 781-796 (1985).
13. C. P. Lin and M. W. Kelly, "Ultrafast time-resolved imaging of stress transient and cavitation from short pulsed laser irradiated melanin, particles," Proc. SPIE 2391A, 294-299 (1995).
14. H. Lee, C. Alt, C. M. Pitsillides, and C. P. Lin, "Optical detection of intracellular cavitation during selective laser targeting of the retinal pigment epithelium: dependence of cell death mechanism on pulse duration," J. Biomed. Opt. 12, 064034 (2007).
15. R. Brinkmann, G. Hüttmann, J. Rögener, J. Roider, R. Birngruber, and C. P. Lin, "Origin of RPE-cell damage by pulsed laser irradiance in the ns to μs time regime," Lasers Surg. Med. 27, 451-464 (2000).
16. S. Y. Schmidt and R. D. Peisch, "Melanin concentration in normal human retinal pigment epithelium," Invest. Ophthalmol. Vis. Sci. 27, 1063-1067 (1986).
17. R. Brinkmann, J. Roider, and R. Birngruber, "Selective retina therapy (SRT): a review on methods, techniques, preclinical and first clinical results," Bull. Soc. Belge. Ophtalmol. 302, 51-69 (2006).