Alphavirus replicon particles acting as adjuvants promote CD8+ T cell responses to co-delivered antigen

Vaccine

Volumn 26, Issue 33, 2008, Pages 4267-4275

  Thompson, Joseph M ^a,b   Whitmore, Alan C ^b   Staats, Herman F ^c   Johnston, Robert E ^a,b  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF NORTH CAROLINA   (United States)

^c DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Cell mediated immunity; Viral adjuvants; Viral vaccine vectors

Indexed keywords

CPG OLIGODEOXYNUCLEOTIDE; GAMMA INTERFERON; HOMING RECEPTOR; IMMUNOGLOBULIN G ANTIBODY; IMMUNOGLOBULIN G1; IMMUNOGLOBULIN G2A; IMMUNOLOGICAL ADJUVANT; OVALBUMIN; TOLL LIKE RECEPTOR; VIRUS REPLICON PARTICLE;

ALPHA VIRUS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIBODY RESPONSE; ANTIGEN SPECIFICITY; ARTICLE; CD8+ T LYMPHOCYTE; CELLULAR IMMUNITY; CONTROLLED STUDY; DENDRITIC CELL; DRUG ACTIVITY; ENCEPHALOMYELITIS; ENZYME LINKED IMMUNOSPOT ASSAY; FEMALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; REPLICON; TH1 CELL; TH2 CELL; UPREGULATION; VIRUS PARTICLE;

ADJUVANTS, IMMUNOLOGIC; ANIMALS; ANTIBODIES; CD8-POSITIVE T-LYMPHOCYTES; DRUG INTERACTIONS; ENCEPHALITIS VIRUS, VENEZUELAN EQUINE; FEMALE; IMMUNITY, MUCOSAL; IMMUNOGLOBULIN G; INTEGRINS; INTERFERON TYPE II; LYMPH NODES; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; OLIGODEOXYRIBONUCLEOTIDES; OVALBUMIN;

EID: 47149102514     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vaccine.2008.05.046     Document Type: Article

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