Synthesis of phosphatidylated-monoterpene alcohols catalyzed by phospholipase D and their antiproliferative effects on human cancer cells

Bioorganic and Medicinal Chemistry Letters

Volumn 18, Issue 14, 2008, Pages 4044-4046

  Yamamoto, Yukihiro ^a   Hosokawa, Masashi ^a   Kurihara, Hideyuki ^a   Maoka, Takashi ^b   Miyashita, Kazuo ^a  

^a HOKKAIDO UNIVERSITY   (Japan)

^b RESEARCH INSTITUTE FOR PRODUCTION DEVELOPMENT   (Japan)

Author keywords

Antiproliferative effect; Phospholipase D; Phospholipids; Terpene alcohol; Transphosphatidylation

Indexed keywords

ALCOHOL DERIVATIVE; MYRTENOL; NEROL; PERILLYL ALCOHOL; PHOSPHATIDYLMYRTENOL; PHOSPHATIDYLNEROL; PHOSPHATIDYLPERIALLYL ALCOHOL; PHOSPHOLIPASE D; PHOSPHOLIPID; TERPENE DERIVATIVE;

ANTINEOPLASTIC ACTIVITY; AQUEOUS SOLUTION; ARTICLE; CELL PROLIFERATION; CELL STRAIN HL 60; CELL VIABILITY; CONTROLLED STUDY; DRUG SYNTHESIS; HUMAN; HUMAN CELL; QUANTUM YIELD; STRUCTURE ACTIVITY RELATION;

ALCOHOLS; ANTINEOPLASTIC AGENTS; CATALYSIS; CELL LINE, TUMOR; CELL PROLIFERATION; DRUG SCREENING ASSAYS, ANTITUMOR; HL-60 CELLS; HUMANS; MODELS, CHEMICAL; MONOTERPENES; PHOSPHOLIPASE D; TERPENES;

EID: 47149098175     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2008.05.113     Document Type: Article

References (17)

1. Deepika R., and Steven P.H. Prostate 57 (2003) 14
2. Heleni L., Maria H., Vassoula S., Evangelia P., Charis R., Fragiskos N.K., and Andreas P. J. Pharmacol. Exp. Ther. 311 (2004) 568
3. Howard H.B., George W., Kendra D.T., Rhoda Z.A., Dona A., Chris F., Kris S., Rebecca M., Sarah A.H., Jan S., Kriste A.L., and Raymond J.H. Cancer Chemother. Pharmacol. 54 (2004) 368
4. Howard H.B., Steven A., Richard R.L., Terri F., Rick C., Kendra T., Linda H., Alcee J., Richard H., Gary R.S., and James A.S. Cancer Chemother. Pharmacol. 62 (2008) 149
5. Shoff S.M., Grummer M., Yatvin M.B., and Elson C.E. Cancer Res. 51 (1991) 37
6. Yu S.G., Hildebrandt L.A., and Elson C.E. J. Nutr. 125 (1995) 2763
7. Carnesecchi S., Langley K., Exinger F., Gosse F., and Raul F. J. Pharmacol. Exp. Ther. 301 (2002) 625
8. Yagi N., Yano Y., Hatanaka K., Yokoyama Y., and Okuno H. Bioorg. Med. Chem. Lett. 17 (2007) 2590
9. Komizu Y., Matsumoto Y., and Ueoka R. Bioorg. Med. Chem. Lett. 16 (2006) 6131
10. Ulbrich-Hofmann R., Lerchner A., Oblozinsky M., and Bezakova L. Biotechnol. Lett. 27 (2005) 535
11. Takami M., and Suzuki Y. Biosci. Biotechnol. Biochem. 58 (1994) 1897
12. Suto S., Itoh H., Sakai A., Nakagami K., Imamura S., and Matsuda A. Bioorg. Med. Chem. 3 (1995) 235
13. Chang Y., Wang Z., Robert H.N., Wang Z., Long Q., and Schwan A.L. Bioorg. Med. Chem. 14 (2004) 5983
14. Iwama S., Segawa M., Fujii S., Ikeda K., and Katsumura S. Bioorg. Med. Chem. 8 (1998) 3495
15. Yamamoto Y., Hosokawa M., Kurihara H., and Miyashita K. J. Am. Oil Chem. Soc. 85 (2008) 313
16. 3, 126 MHz): δ 173.5, 139.3, 131.7, 130.0, 123.9, 122.3, 70.5, 63.5, 63.0, 62.3, 34.3, 31.9, 31.27 (several C's), 27.2, 24.9, 24.8, 23.4, 23.4, 17.7, 14.1.
17. Mosmann T. J. Immunol. Methods 16 (1983) 55