Oral salbutamol for symptomatic relief in mild bronchiolitis: A double blind randomized placebo controlled trial

Indian Pediatrics

Volumn 45, Issue 7, 2008, Pages 547-553

  Gupta, Pankaj ^a   Aggarwal, Anju ^a   Gupta, Piyush ^a,b   Sharma, K K ^a  

^a UNIVERSITY COLLEGE OF MEDICAL SCIENCES   (India)

^b NONE   (India)

Author keywords

Bronchiolitis; Bronchodilators; Infants; Salbutamol

Indexed keywords

HEMOGLOBIN; PARACETAMOL; PLACEBO; SALBUTAMOL;

AMBIENT AIR; ARTICLE; BLOOD OXYGEN TENSION; BREATHING DISORDER; BREATHING RATE; BRONCHIOLITIS; CLINICAL TRIAL; COMMON COLD; CONFIDENCE INTERVAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; COUGHING; DISEASE DURATION; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; FEVER; FOLLOW UP; HEART RATE; HEMOGLOBIN BLOOD LEVEL; HOSPITALIZATION; HUMAN; INFANT; MAJOR CLINICAL STUDY; OUTCOME ASSESSMENT; OUTPATIENT DEPARTMENT; PEDIATRIC HOSPITAL; RANDOMIZED CONTROLLED TRIAL; RESOLUTION OF ILLNESS; RESPIRATORY DISTRESS ASSESSMENT INSTRUMENT; SCORING SYSTEM; SLEEP; SYMPTOM; TERTIARY HEALTH CARE; TREATMENT DURATION; TREMOR;

ACUTE DISEASE; ADMINISTRATION, ORAL; ALBUTEROL; BRONCHIOLITIS; BRONCHODILATOR AGENTS; CHILD; DOUBLE-BLIND METHOD; FEMALE; HEART FAILURE; HUMANS; INFANT; MALE; SEVERITY OF ILLNESS INDEX; TREATMENT OUTCOME;

EID: 47049113638     PISSN: 00196061     EISSN: 00196061     Source Type: Journal    
DOI: None     Document Type: Article

References (17)

1. Vogel AM, Lennon DR, Harding JE, Pinnock RE. Variation in bronchiolitis management between five New Zealand hospitals. Can we do better? J Pediatr Child Health 2003; 39: 40-45.
2. King VJ, Viswanaththan M, Bordley WC, Jackman AM, Sutton SF, Lohr KN, et al. Pharmacological treatment of bronchiolitis in infants and children. Arch Paediatr Adolesc Med 2004; 158: 127-137.
3. Patel H, Gouin S, Platt RW. Randomized double blind, placebo-controlled trial of oral albuterol in infant with mild-moderate acute bronchiolitis. J Pediatr 2003; 142: 509-514.
4. Newcomb RW. Use of adrenergic bronchodilators by pediatric allergist and pulmonologist. AJDC 1989; 193: 481-485.
5. Schweich PJ, Hurt TL, Walkley EI, Mullen N, Archibald LF. The use of nebulized albuterol in wheezing infants. Pediatr Emerg Care 1992; 8: 184-188.
6. Reijonen T, Korppi M, Pitkakangas S, Tenhola S, Remes K. The clinical efficacy of nebulized epinephrine and albuterol in acute bronchiolitis. Arch Pediatr Adolesc Med 1995; 149: 686-692.
7. Kellner JD, Gadmoski AM, Ohlsson A, Wang EEL. Efficacy of bronchodilator therapy in bronchiolitis: A meta-analysis. Arch Pediatr Adolesc Med 1996; 150: 1166-1172.
8. Klassen TP, Rowe PC, Sutchliffe T, Ropp LJ, McDowell IW, Marilyn M. Randomized trial of Salbutamol in acute bronchiolitis. J Pediatr 1991; 118: 807-811.
9. Schuh S, Canny G, Reisman JJ, Keren E, Bentur L, Petric M, et al. Nebulized salbuterol in acute bronchiolitis. J Pediatr 1990; 117: 633-637.
10. Cengizilier R, Saraclar Y, Adalioglu G, Tuncer A. Effect of oral and inhaled salbutamol in infants with bronchiolitis. Acta Paediatr Jpn 1997; 39: 61-63.
11. Flores G, Horwitz RI. Efficacy of β2-agonist in bronchiolitis: A reappraisal and meta-analysis. Pediatrics 1997; 100: 233-239.
12. Wang EEL, Milner R, Allen V, Maj N. Bronchodilators for treatment of mild bronchiolitis. A factorial randomized trial. Arch Dis Child 1992; 67: 289-293.
13. Ho L, Collin G, Landau LI, Le Souef PN. Effect of salbutamol on oxygen saturation in bronchiolitis. Arch Dis Child 1991; 66: 1061-1064.
14. Hughes DM, Lesouef PN, Landau LI. Effect of salbutamol on respiratory mechanisms in bronchiolitis. Pediatr Res 1987; 22: 83-86.
15. Lowell DI, Lister G, Von Koss H, McCarthy P. Wheezing in infants: response to epinephrine. Pediatrics 1987; 79: 939-945.
16. Gadomski AM, Aref GH, El Din OB, El Sawy IH, Khallaf N, Black RE. Oral versus nebulized albuterol in the management of bronchiolitis in Egypt. J Pediatr 1994; 124: 131-138.
17. Gadomski AM, Lichenstein R, Horton L, King J, Keane V, Permutt D. Efficacy of albuterol in the management of bronchiolitis. Pediatrics 1993; 93: 907-912.