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One of the best examples of a large, multicenter trial utilizing a modern response-adapted approach to the treatment of all stages of pediatric Hodgkin lymphoma
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Ruhl U, Albrecht MR, Lueders H, et al.: Abstract at ASTRO, 46th annual meeting: The German multinational GPOH-HD 95 trial: Treatment results and analysis of failures in pediatric Hodgkins disease using combination chemotherapy with and without radiation. Int J Radiat Oncol Biol Phys 2004, 60:S131
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22
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An excellent trial highlighting the central debate in treatment of pediatric Hodgkin lymphoma-whether or not radiotherapy should be employed
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NnachmanJB, Sposto P., Herzog, et al.: Randomized comparison of low-dose involved-field radiotherapy and no radiotherapy for children with Hodgkin's disease who achieve a complete response to chemotherapy. J Clin Oncol 2002, 20(18):3765-3771. An excellent trial highlighting the central debate in treatment of pediatric Hodgkin lymphoma-whether or not radiotherapy should be employed
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Glick JH, Young ML, Harrington D, et al.: MOPP/ABV hybrid chemotherapy for advanced Hodgkin's disease significantly improves failure-free and overall survival: The 8-year results of the intergroup trial. J Clin Oncol 1998, 16(1):19-26. A study highlighting the trade-off between the use of radiation therapy and the decreased event-free survival of its omission
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