No reflow-like pattern in intramyocardial coronary artery suggests myocardial ischemia in patients with hypertrophic cardiomyopathy

Journal of Cardiology

Volumn 52, Issue 1, 2008, Pages 7-16

  Kim, Woo Shik ^a   Minagoe, Shinichi ^b   Mizukami, Naoko ^a   Zhou, Xiaoyan ^a   Yoshinaga, Keiichiro ^a   Takasaki, Kunitsugu ^a   Yuasa, Toshinori ^a   Kihara, Koichi ^a   Hamasaki, Shuichi ^a   Otsuji, Yutaka ^a   Kisanuki, Akira ^a   Tei, Chuwa ^a  

^a KAGOSHIMA UNIVERSITY   (Japan)

^b NATIONAL HOSPITAL ORGANIZATION KAGOSHIMA MEDICAL CENTER   (Japan)

Author keywords

Cardiomyopathies; Coronary microcirculation; Echocardiography; Hypertrophic

Indexed keywords

THALLIUM 201;

ADULT; ARTICLE; BLOOD FLOW; CLINICAL ARTICLE; CONTROLLED STUDY; CORONARY ARTERY; DOPPLER ECHOCARDIOGRAPHY; EXERCISE; FEMALE; FLOW RATE; HEART MUSCLE ISCHEMIA; HUMAN; HYPERTROPHIC CARDIOMYOPATHY; INCIDENCE; LEFT ANTERIOR DESCENDING CORONARY ARTERY; MALE; SCINTIGRAPHY; SYMPTOMATOLOGY; SYNCOPE; THORAX PAIN;

ADULT; CARDIOMYOPATHY, HYPERTROPHIC; CORONARY VESSELS; ECHOCARDIOGRAPHY, DOPPLER; FEMALE; HUMANS; MALE; MIDDLE AGED; MYOCARDIAL ISCHEMIA; RADIOPHARMACEUTICALS; THALLIUM RADIOISOTOPES;

EID: 47049089553     PISSN: 09145087     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jjcc.2008.04.004     Document Type: Article

References (30)

1. Maron B.J., Epstein S.E., and Roberts W.C. Hypertrophic cardiomyopathy and transmural myocardial infarction without significant atherosclerosis of the extramural coronary arteries. Am J Cardiol 43 (1979) 1086-1102
2. Pasternac A., Noble J., Streulens Y., Elie R., Henschke C., and Bourassa M.G. Pathophysiology of chest pain in patients with cardiomyopathies and normal coronary arteries. Circulation 65 (1982) 778-779
3. Cannon 3d R.O., Rosing D.R., Maron B.J., Leon M.B., Bonow R.O., Watson R.M., et al. Myocardial ischemia in patients with hypertrophic cardiomyopathy: contribution of inadequate vasodilator reserve and elevated left ventricular filling pressures. Circulation 71 (1985) 234-243
4. Maron B.J., Wolfson J.K., Epstein S.E., and Roberts W.C. Intramural ("small vessel") coronary artery disease in hypertrophic cardiomyopathy. J Am Coll Cardiol 8 (1986) 545-557
5. Tomochika Y., Tanaka N., Wasaki Y., Shimizu H., Hiro J., Takahashi T., et al. Assessment of flow profile of left anterior descending coronary artery in hypertrophic cardiomyopathy by transesophageal pulsed Doppler echocardiography. Am J Cardiol 72 (1993) 1425-1430
6. Akasaka T., Yoshikawa J., Yoshida K., Maeda K., Takagi T., and Miyake S. Phasic coronary flow characteristics in patients with hypertrophic cardiomyopathy: a study by coronary Doppler catheter. J Am Soc Echocardiogr 7 (1994) 9-19
7. Crowley J.J., Dardas P.S., Harcombe A.A., and Shapiro L.M. Transthoracic Doppler echocardiographic analysis of phasic coronary blood flow velocity in hypertrophic cardiomyopathy. Heart 77 (1997) 558-563
8. Chilian W.M., and Marcus M.L. Phasic coronary blood flow velocity in intramural and epicardial coronary arteries. Circ Res 50 (1982) 775-781
9. Minagoe S., Toyama Y., Niizoe K., Yamaguchi H., Toyoshima S., Umebayashi Y., et al. Transthoracic Doppler echocardiographic detection of intramyocardial coronary artery flow in humans using high frequency transducer. J Cardiol 30 (1997) 149-155
10. Hirasaki S., Nakamura T., Kuribayashi T., Shima T., Matsubara K., Azuma A., et al. Abnormal course, abnormal flow, and systolic compression of the septal perforator associated with impaired myocardial perfusion in hypertrophic cardiomyopathy. Am Heart J 137 (1999) 109-117
11. Youn H.-J., Redberg R.F., Schiller N.B., and Foster E. Demonstration of penetrating intramyocardial coronary arteries with high-frequency transthoracic echocardiography and Doppler in human subjects. J Am Soc Echocardiogr 12 (1999) 55-63
12. Watanabe N., Akasaka T., Yamaura Y., Akiyama M., Kaji S., Saito Y., et al. Intramyocardial coronary flow characteristics in patients with hypertrophic cardiomyopathy: non-invasive assessment by transthoracic Doppler echocardiography. Heart 89 (2003) 657-658
13. Richardson P., McKenna W., Bristow M., Maisch B., Mautner B., O'Connell J., et al. Report of the 1995 world health organization/international society and federation of cardiology task force on the definition and classification of cardiomyopathies. Circulation 93 (1996) 841-842
14. Hamasaki S., Nakano F., Arima S., Tahara M., Kamekou M., Fukumoto N., et al. A new criterion combining ST/HR slope and ΔST/ΔHR index for detection of coronary artery disease in patients on digoxin therapy. Am J Cardiol 81 (1998) 1100-1104
15. Pitcher D., Wainwright R., Maisey M., Curry P., and Sowton E. Assessment of chest pain in hypertrophic cardiomyopathy using exercise thallium-201 myocardial scintigraphy. Br Heart J 44 (1980) 650-656
16. Shintani Y., Ito H., Iwakura K., Kawano S., Tanaka K., Masuyama T., et al. Usefulness of impairment of coronary microcirculation in predicting left ventricular dilation after acute myocardial infarction. Am J Cardiol 93 (2004) 974-978
17. Irvine T., and Kenny A. Aortic stenosis and angina with normal coronary arteries: the role of coronary flow abnormalities. Heart 78 (1997) 213-214
18. Iwakura K., Ito H., Takiuchi S., Taniyama Y., Nakatsuchi Y., Negoro S., et al. Alternative in the coronary blood flow velocity pattern in patients with no reflow and reperfused acute myocardial infarction. Circulation 94 (1996) 1269-1275
19. Bellamy R.F. Diastolic coronary artery pressure-flow relations in the dog. Circ Res 43 (1978) 92-101
20. Klocke F.J. Measurements of coronary flow reserve: defining pathophysiology versus making decisions about patient care. Circulation 76 (1987) 1183-1189
21. Duncker D.J., Zhang J., and Bache R.J. Coronary pressure-flow relation in left ventricular hypertrophy. Importance of changes in back pressure versus changes in minimum resistance. Circ Res 72 (1993) 579-587
22. Schwartzkopff B., Mundhenke M., and Strauer B.E. Alterations of the architecture of subendocardial arterioles in patients with hypertrophic cardiomyopathy and impaired coronary vasodilator reserve: a possible cause for myocardial ischemia. J Am Coll Cardiol 31 (1998) 1089-1096
23. Dimitrow P.P., and Dubiel J.S. Impairment of coronary microvascular flow in hypertrophic cardiomyopathy. Eur Heart J 23 (2002) 991
24. Tanaka M., Fujiwara H., Onodera T., Wu D.-J., Matsuda M., Hamashima Y., et al. Quantitative analysis of narrowings of intramyocardial small arteries in normal hearts, hypertensive hearts, and hearts with hypertrophic cardiomyopathy. Circulation 75 (1987) 1130-1139
25. Nishimura T. Approaches to identify and characterize hypertrophic myocardium. J Nucl Med 34 (1993) 1013-1019
26. Dilsizian V., Bonow R.O., Epstein S.E., and Fananapazir L. Myocardial ischemia detected by thallium scintigraphy is frequently related to cardiac arrest and syncope in young patients with hypertrophic cardiomyopathy. J Am Coll Cardiol 22 (1993) 796-804
27. Cannon III R.O., Dilsizian V., O'Gara P.T., Schenke W.H., Quyyumi A., Fananapazir L., et al. Myocardial metabolic, hemodynamic, and electrocardiographic significance of reversible thallium-201 abnormalities in hypertrophic cardiomyopathy. Circulation 83 (1991) 1660-1667
28. Udelson J.E., Bonow R.O., O'Gara P.T., Maron B.J., Lingen A.V., Bacharach S.L., et al. Verapamil prevents silent myocardial perfusion abnormalities during exercise in asymptomatic patients with hypertrophic cardiomyopathy. Circulation 79 (1989) 1052-1060
29. Kraitchman D.L., Chin B.B., Heldman A.W., Solaiyappan M., and Bluemke D.A. MRI detection of myocardial perfusion defects due to coronary artery stenosis with MS-325. J Magn Reson Imaging 15 (2002) 149-158
30. Cecchi F., Olivotto I., Gistri R., Lorenzoni R., Chiriatti G., and Camici P.G. Coronary microvascular dysfunction and prognosis in hypertrophic cardiomyopathy. N Engl J Med 349 (2003) 1027-1035