메뉴 건너뛰기




Volumn 68, Issue 4, 2008, Pages 260-269

Genesis of hepatic fibrosis and its biochemical markers

Author keywords

Collagen; Cytokines; Extracellular matrix; Fibrosis; Hepatic stellate cell; Hyaluronic acid; Interleukins; Matrix metalloproteinases; Transforming growth factor beta

Indexed keywords

BIOCHEMICAL MARKER; COLLAGEN FIBER; MATRIX METALLOPROTEINASE; TISSUE INHIBITOR OF METALLOPROTEINASE;

EID: 46949105856     PISSN: 00365513     EISSN: 15027686     Source Type: Journal    
DOI: 10.1080/00365510701668516     Document Type: Review
Times cited : (41)

References (92)
  • 1
    • 33644499498 scopus 로고    scopus 로고
    • Reversal of hepatic fibrosis: Fact or fantasy
    • Friedman SL, Bansal MB. Reversal of hepatic fibrosis: fact or fantasy. Hepatology 2006;43:S82-8.
    • (2006) Hepatology , vol.43
    • Friedman, S.L.1    Bansal, M.B.2
  • 2
    • 33747584867 scopus 로고    scopus 로고
    • Hepatic stellate cells and the reversal of fibrosis
    • Kisseleva T, Brenner DA. Hepatic stellate cells and the reversal of fibrosis. J Gastroenterol Hepatol 2006;21 Suppl 3:S84-7.
    • (2006) J Gastroenterol Hepatol , vol.21 , Issue.SUPPL. 3
    • Kisseleva, T.1    Brenner, D.A.2
  • 3
    • 0034723290 scopus 로고    scopus 로고
    • Molecular regulation of hepatic fibrosis, an integrated cellular response to tissue injury
    • Friedman SL. Molecular regulation of hepatic fibrosis, an integrated cellular response to tissue injury. J Biol Chem 2000;275:2247-50.
    • (2000) J Biol Chem , vol.275 , pp. 2247-2250
    • Friedman, S.L.1
  • 5
    • 33644525672 scopus 로고    scopus 로고
    • Hepatic stellate cells: Their role in normal and pathological conditions
    • Sarem M, Znaidak R, Macias M, Rey R. Hepatic stellate cells: their role in normal and pathological conditions. Gastroenterol Hepatol 2006;29:93-101.
    • (2006) Gastroenterol Hepatol , vol.29 , pp. 93-101
    • Sarem, M.1    Znaidak, R.2    Macias, M.3    Rey, R.4
  • 6
    • 0036551274 scopus 로고    scopus 로고
    • Activation of hepatic stellate cells - a key issue in liver fibrosis
    • Reeves HL, Friedman SL. Activation of hepatic stellate cells - a key issue in liver fibrosis. Front Biosci 2002;7:d808-26.
    • (2002) Front Biosci , vol.7
    • Reeves, H.L.1    Friedman, S.L.2
  • 7
    • 0742295936 scopus 로고    scopus 로고
    • Chemokines in liver inflammation and fibrosis
    • Marra F. Chemokines in liver inflammation and fibrosis. Front Biosci 2002;7:d1899-914.
    • (2002) Front Biosci , vol.7
    • Marra, F.1
  • 8
    • 0842300376 scopus 로고    scopus 로고
    • Hepatitis C virus core and nonstructural proteins induce fibrogenic effects in hepatic stellate cells
    • Bataller R, Paik YH, Lindquist JN, Lemasters JJ, Brenner DA. Hepatitis C virus core and nonstructural proteins induce fibrogenic effects in hepatic stellate cells. Gastroenterology 2004;126:529-40.
    • (2004) Gastroenterology , vol.126 , pp. 529-540
    • Bataller, R.1    Paik, Y.H.2    Lindquist, J.N.3    Lemasters, J.J.4    Brenner, D.A.5
  • 9
    • 0036298016 scopus 로고    scopus 로고
    • Up-regulated expression of fractalkine and its receptor CX3CR1 during liver injury in humans
    • Efsen E, Grappone C, DeFranco RM, Milani S, Romanelli RG, Bonacchi A, et al. Up-regulated expression of fractalkine and its receptor CX3CR1 during liver injury in humans. J Hepatol 2002;37:39-47.
    • (2002) J Hepatol , vol.37 , pp. 39-47
    • Efsen, E.1    Grappone, C.2    DeFranco, R.M.3    Milani, S.4    Romanelli, R.G.5    Bonacchi, A.6
  • 10
    • 0038185316 scopus 로고    scopus 로고
    • Toll-like receptor 4 mediates inflammatory signaling by bacterial lipopolysaccharide in human hepatic stellate cells
    • Paik YH, Schwabe RF, Bataller R, Russo MP, Jobin C, Brenner DA. Toll-like receptor 4 mediates inflammatory signaling by bacterial lipopolysaccharide in human hepatic stellate cells. Hepatology 2003;37:1043-55.
    • (2003) Hepatology , vol.37 , pp. 1043-1055
    • Paik, Y.H.1    Schwabe, R.F.2    Bataller, R.3    Russo, M.P.4    Jobin, C.5    Brenner, D.A.6
  • 12
    • 0037371341 scopus 로고    scopus 로고
    • Proangiogenic role of tumor-activated hepatic stellate cells in experimental melanoma metastasis
    • Olaso E, Salado C, Egilegor E, Gutierrez V, Santisteban A, Sancho-Bru P, et al. Proangiogenic role of tumor-activated hepatic stellate cells in experimental melanoma metastasis. Hepatology 2003;37:674-85.
    • (2003) Hepatology , vol.37 , pp. 674-685
    • Olaso, E.1    Salado, C.2    Egilegor, E.3    Gutierrez, V.4    Santisteban, A.5    Sancho-Bru, P.6
  • 13
    • 0033980284 scopus 로고    scopus 로고
    • Hypoxic stimulation of vascular endothelial growth factor expression in activated rat hepatic stellate cells
    • Ankoma-Sey V, Wang Y, Dai Z. Hypoxic stimulation of vascular endothelial growth factor expression in activated rat hepatic stellate cells. Hepatology 2000;31:141-8.
    • (2000) Hepatology , vol.31 , pp. 141-148
    • Ankoma-Sey, V.1    Wang, Y.2    Dai, Z.3
  • 14
    • 2442724379 scopus 로고
    • Transforming growth factor beta modulates the expression of collagenase and metalloproteinase inhibitor
    • Edwards DR, Murphy G, Reynolds JJ, Whitham SE, Docherty AJ, Angel P, et al. Transforming growth factor beta modulates the expression of collagenase and metalloproteinase inhibitor. EMBO J 1987;6:1899-904.
    • (1987) EMBO J , vol.6 , pp. 1899-1904
    • Edwards, D.R.1    Murphy, G.2    Reynolds, J.J.3    Whitham, S.E.4    Docherty, A.J.5    Angel, P.6
  • 15
    • 0042092032 scopus 로고    scopus 로고
    • Connective tissue growth factor (CTGF/CCN2) in hepatic fibrosis
    • Rachfal AW, Brigstock DR. Connective tissue growth factor (CTGF/CCN2) in hepatic fibrosis. Hepatol Res 2003;26:1-9.
    • (2003) Hepatol Res , vol.26 , pp. 1-9
    • Rachfal, A.W.1    Brigstock, D.R.2
  • 16
    • 0034680787 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptors and hepatic stellate cell activation
    • Miyahara T, Schrum L, Rippe R, Xiong S, Yee HF Jr, Motomura K, et al. Peroxisome proliferator-activated receptors and hepatic stellate cell activation. J Biol Chem 2000;275:35715-22.
    • (2000) J Biol Chem , vol.275 , pp. 35715-35722
    • Miyahara, T.1    Schrum, L.2    Rippe, R.3    Xiong, S.4    Yee Jr, H.F.5    Motomura, K.6
  • 18
    • 33645243410 scopus 로고    scopus 로고
    • Phagocytosis of apoptotic bodies by hepatic stellate cells induces NADPH oxidase and is associated with liver fibrosis in vivo
    • Zhan SS, Jiang JX, Wu J, Halsted C, Friedman SL, Zern MA, et al. Phagocytosis of apoptotic bodies by hepatic stellate cells induces NADPH oxidase and is associated with liver fibrosis in vivo. Hepatology 2006;43:435-43.
    • (2006) Hepatology , vol.43 , pp. 435-443
    • Zhan, S.S.1    Jiang, J.X.2    Wu, J.3    Halsted, C.4    Friedman, S.L.5    Zern, M.A.6
  • 19
    • 22344450669 scopus 로고    scopus 로고
    • Cell type-specific intervention of transforming growth factor beta/Smad signaling suppresses collagen gene expression and hepatic fibrosis in mice
    • Inagaki Y, Kushida M, Higashi K, Itoh J, Higashiyama R, Hong YY, et al. Cell type-specific intervention of transforming growth factor beta/Smad signaling suppresses collagen gene expression and hepatic fibrosis in mice. Gastroenterology 2005;129:259-68.
    • (2005) Gastroenterology , vol.129 , pp. 259-268
    • Inagaki, Y.1    Kushida, M.2    Higashi, K.3    Itoh, J.4    Higashiyama, R.5    Hong, Y.Y.6
  • 20
    • 24344500807 scopus 로고    scopus 로고
    • Smad2 and Smad3 play different roles in rat hepatic stellate cell function and alpha-smooth muscle actin organization
    • Uemura M, Swenson ES, Gaca MD, Giordano FJ, Reiss M, Wells RG. Smad2 and Smad3 play different roles in rat hepatic stellate cell function and alpha-smooth muscle actin organization. Mol Biol Cell 2005;16:4214-24.
    • (2005) Mol Biol Cell , vol.16 , pp. 4214-4224
    • Uemura, M.1    Swenson, E.S.2    Gaca, M.D.3    Giordano, F.J.4    Reiss, M.5    Wells, R.G.6
  • 21
    • 15444375634 scopus 로고    scopus 로고
    • SMAD and p38 MAPK signaling pathways independently regulate alpha1(I) collagen gene expression in unstimulated and transforming growth factor-beta-stimulated hepatic stellate cells
    • Tsukada S, Westwick JK, Ikejima K, Sato N, Rippe RA. SMAD and p38 MAPK signaling pathways independently regulate alpha1(I) collagen gene expression in unstimulated and transforming growth factor-beta-stimulated hepatic stellate cells. J Biol Chem 2005;280:10055-64.
    • (2005) J Biol Chem , vol.280 , pp. 10055-10064
    • Tsukada, S.1    Westwick, J.K.2    Ikejima, K.3    Sato, N.4    Rippe, R.A.5
  • 24
    • 0034809414 scopus 로고    scopus 로고
    • Hepatic stellate cell behavior during resolution of liver injury
    • Iredale JP. Hepatic stellate cell behavior during resolution of liver injury. Semin Liver Dis 2001;21:427-36.
    • (2001) Semin Liver Dis , vol.21 , pp. 427-436
    • Iredale, J.P.1
  • 25
    • 0029888478 scopus 로고    scopus 로고
    • Tissue inhibitor of metalloproteinase-1 messenger RNA expression is enhanced relative to interstitial collagenase messenger RNA in experimental liver injury and fibrosis
    • Iredale JP, Benyon RC, Arthur MJ, Ferris WF, Alcolado R, Winwood PJ, et al. Tissue inhibitor of metalloproteinase-1 messenger RNA expression is enhanced relative to interstitial collagenase messenger RNA in experimental liver injury and fibrosis. Hepatology 1996;24:176-84.
    • (1996) Hepatology , vol.24 , pp. 176-184
    • Iredale, J.P.1    Benyon, R.C.2    Arthur, M.J.3    Ferris, W.F.4    Alcolado, R.5    Winwood, P.J.6
  • 28
    • 0031025218 scopus 로고    scopus 로고
    • Membrane type 1 matrix metalloproteinase digests interstitial collagens and other extracellular matrix macromolecules
    • Ohuchi E, Imai K, Fujii Y, Sato H, Seiki M, Okada Y. Membrane type 1 matrix metalloproteinase digests interstitial collagens and other extracellular matrix macromolecules. J Biol Chem 1997;272:2446-51.
    • (1997) J Biol Chem , vol.272 , pp. 2446-2451
    • Ohuchi, E.1    Imai, K.2    Fujii, Y.3    Sato, H.4    Seiki, M.5    Okada, Y.6
  • 29
    • 0032835380 scopus 로고    scopus 로고
    • Matrix metalloproteinase-2 activation in human hepatic fibrosis regulation by cell-matrix interactions
    • Preaux AM, Mallat A, Nhieu JT, D'Ortho MP, Hembry RM, Mavier P. Matrix metalloproteinase-2 activation in human hepatic fibrosis regulation by cell-matrix interactions. Hepatology 1999;30:944-50.
    • (1999) Hepatology , vol.30 , pp. 944-950
    • Preaux, A.M.1    Mallat, A.2    Nhieu, J.T.3    D'Ortho, M.P.4    Hembry, R.M.5    Mavier, P.6
  • 30
    • 10244241848 scopus 로고    scopus 로고
    • Dynamic changes in the expression of matrix metalloproteinases and their inhibitors, TIMPs, during hepatic fibrosis induced by alcohol in rats
    • Xu GF, Li PT, Wang XY, Jia X, Tian DL, Jiang LD, et al. Dynamic changes in the expression of matrix metalloproteinases and their inhibitors, TIMPs, during hepatic fibrosis induced by alcohol in rats. World J Gastroenterol 2004;10:3621-7.
    • (2004) World J Gastroenterol , vol.10 , pp. 3621-3627
    • Xu, G.F.1    Li, P.T.2    Wang, X.Y.3    Jia, X.4    Tian, D.L.5    Jiang, L.D.6
  • 31
    • 0033198966 scopus 로고    scopus 로고
    • Serum matrix metalloproteinase-3 (stromelysin-1) concentration in patients with chronic liver disease
    • Murawaki Y, Ikuta Y, Okamoto K, Koda M, Kawasaki H. Serum matrix metalloproteinase-3 (stromelysin-1) concentration in patients with chronic liver disease. J Hepatol 1999;31:474-81.
    • (1999) J Hepatol , vol.31 , pp. 474-481
    • Murawaki, Y.1    Ikuta, Y.2    Okamoto, K.3    Koda, M.4    Kawasaki, H.5
  • 32
    • 20444503484 scopus 로고    scopus 로고
    • Dynamic evolution of MMP-13, TIMP-1, type I and III collagen and their interaction in experimental liver fibrosis
    • Zhu YK, Wang BE, Shen FJ, Wang AM, Jia JD, Ma H. Dynamic evolution of MMP-13, TIMP-1, type I and III collagen and their interaction in experimental liver fibrosis. Zhonghua Gan Zang Bing Za Zhi 2004;12:612-15.
    • (2004) Zhonghua Gan Zang Bing Za Zhi , vol.12 , pp. 612-615
    • Zhu, Y.K.1    Wang, B.E.2    Shen, F.J.3    Wang, A.M.4    Jia, J.D.5    Ma, H.6
  • 33
    • 16644402719 scopus 로고    scopus 로고
    • Expression of matrix metalloproteinase-2 and -14 persists during early resolution of experimental liver fibrosis and might contribute to fibrolysis
    • Zhou X, Hovell CJ, Pawley S, Hutchings MI, Arthur MJ, Iredale JP, et al. Expression of matrix metalloproteinase-2 and -14 persists during early resolution of experimental liver fibrosis and might contribute to fibrolysis. Liver Int 2004;24:492-501.
    • (2004) Liver Int , vol.24 , pp. 492-501
    • Zhou, X.1    Hovell, C.J.2    Pawley, S.3    Hutchings, M.I.4    Arthur, M.J.5    Iredale, J.P.6
  • 35
    • 2642517210 scopus 로고    scopus 로고
    • Dominant-negative soluble PDGF-beta receptor inhibits hepatic stellate cell activation and attenuates liver fibrosis
    • Borkham-Kamphorst E, Herrmann J, Stoll D, Treptau J, Gressner AM, Weiskirchen R. Dominant-negative soluble PDGF-beta receptor inhibits hepatic stellate cell activation and attenuates liver fibrosis. Lab Invest 2004;84:766-77.
    • (2004) Lab Invest , vol.84 , pp. 766-777
    • Borkham-Kamphorst, E.1    Herrmann, J.2    Stoll, D.3    Treptau, J.4    Gressner, A.M.5    Weiskirchen, R.6
  • 36
    • 17144377431 scopus 로고    scopus 로고
    • The role of p70S6K in hepatic stellate cell collagen gene expression and cell proliferation
    • Gabele E, Reif S, Tsukada S, Bataller R, Yata Y, Morris T, et al. The role of p70S6K in hepatic stellate cell collagen gene expression and cell proliferation. J Biol Chem 2005;280:13374-82.
    • (2005) J Biol Chem , vol.280 , pp. 13374-13382
    • Gabele, E.1    Reif, S.2    Tsukada, S.3    Bataller, R.4    Yata, Y.5    Morris, T.6
  • 37
    • 10444259625 scopus 로고    scopus 로고
    • TGF beta1 and PDGF AA override collagen type I inhibition of proliferation in human liver connective tissue cells
    • Geremias AT, Carvalho MA, Borojevic R, Monteiro AN. TGF beta1 and PDGF AA override collagen type I inhibition of proliferation in human liver connective tissue cells. BMC Gastroenterol 2004;4:30.
    • (2004) BMC Gastroenterol , vol.4 , pp. 30
    • Geremias, A.T.1    Carvalho, M.A.2    Borojevic, R.3    Monteiro, A.N.4
  • 40
    • 0028434387 scopus 로고
    • Hepatic lipocytes, TIMP-1 and liver fibrosis
    • Arthur MJ, Iredale JP. Hepatic lipocytes, TIMP-1 and liver fibrosis. J R Coll Phys Lond 1994;28:200-8.
    • (1994) J R Coll Phys Lond , vol.28 , pp. 200-208
    • Arthur, M.J.1    Iredale, J.P.2
  • 42
    • 1942470986 scopus 로고    scopus 로고
    • Cirrhosis reversal: A duel between dogma and myth
    • Desmet VJ, Roskams T. Cirrhosis reversal: a duel between dogma and myth. J Hepatol 2004;40:860-7.
    • (2004) J Hepatol , vol.40 , pp. 860-867
    • Desmet, V.J.1    Roskams, T.2
  • 43
    • 0036242165 scopus 로고    scopus 로고
    • Impact of pegylated interferon alpha-2b and ribavirin on liver fibrosis in patients with chronic hepatitis C
    • Poynard T, McHutchison J, Manns M, Trepo C, Lindsay K, Goodman Z, et al. Impact of pegylated interferon alpha-2b and ribavirin on liver fibrosis in patients with chronic hepatitis C. Gastroenterology 2002;122:1303-13.
    • (2002) Gastroenterology , vol.122 , pp. 1303-1313
    • Poynard, T.1    McHutchison, J.2    Manns, M.3    Trepo, C.4    Lindsay, K.5    Goodman, Z.6
  • 44
    • 2942622398 scopus 로고    scopus 로고
    • Spontaneous recovery from micronodular cirrhosis: Evidence for incomplete resolution associated with matrix cross-linking
    • Issa R, Zhou X, Constandinou CM, Fallowfield J, Millward-Sadler H, Gaca MD, et al. Spontaneous recovery from micronodular cirrhosis: evidence for incomplete resolution associated with matrix cross-linking. Gastroenterology 2004;126:1795-808.
    • (2004) Gastroenterology , vol.126 , pp. 1795-1808
    • Issa, R.1    Zhou, X.2    Constandinou, C.M.3    Fallowfield, J.4    Millward-Sadler, H.5    Gaca, M.D.6
  • 45
    • 0042265556 scopus 로고    scopus 로고
    • A simple noninvasive index can predict both significant fibrosis and cirrhosis in patients with chronic hepatitis C
    • Wai CT, Greenson JK, Fontana RJ, Kalbfleisch JD, Marrero JA, Conjeevaram HS, et al. A simple noninvasive index can predict both significant fibrosis and cirrhosis in patients with chronic hepatitis C. Hepatology 2003;38:518-26.
    • (2003) Hepatology , vol.38 , pp. 518-526
    • Wai, C.T.1    Greenson, J.K.2    Fontana, R.J.3    Kalbfleisch, J.D.4    Marrero, J.A.5    Conjeevaram, H.S.6
  • 47
    • 46949096338 scopus 로고    scopus 로고
    • Utility of serum hydroxyproline, type IV collagen and AST to platelet ratio index (APRI) in the prediction of liver damage
    • abstract
    • Das SK, Balakrishnan V, Vasudevan DM. Utility of serum hydroxyproline, type IV collagen and AST to platelet ratio index (APRI) in the prediction of liver damage. Clin Chem 2007;S6:A77 [abstract].
    • (2007) Clin Chem , vol.S6
    • Das, S.K.1    Balakrishnan, V.2    Vasudevan, D.M.3
  • 48
    • 2342573592 scopus 로고    scopus 로고
    • Improved prediction of fibrosis in chronic hepatitis C using measures of insulin resistance as probability index
    • Sud A, Hui JM, Farrell GC, Bandara P, Kench JG, Fung C, et al. Improved prediction of fibrosis in chronic hepatitis C using measures of insulin resistance as probability index. Hepatology 2004;39:1239-47.
    • (2004) Hepatology , vol.39 , pp. 1239-1247
    • Sud, A.1    Hui, J.M.2    Farrell, G.C.3    Bandara, P.4    Kench, J.G.5    Fung, C.6
  • 50
    • 0034983754 scopus 로고    scopus 로고
    • Hepatic fibrosis plays a central role in the pathogenesis of thrombocytopenia in patients with chronic viral hepatitis
    • Adinolfi LE, Giordano MG, Andreana A, Tripodi MF, Utili R, Cesaro G, et al. Hepatic fibrosis plays a central role in the pathogenesis of thrombocytopenia in patients with chronic viral hepatitis. Br J Haemotol 2001;113:590-5.
    • (2001) Br J Haemotol , vol.113 , pp. 590-595
    • Adinolfi, L.E.1    Giordano, M.G.2    Andreana, A.3    Tripodi, M.F.4    Utili, R.5    Cesaro, G.6
  • 51
    • 0021804624 scopus 로고
    • Plasma clearance of intravenously injected aspartate aminotransferase isoenzymes; evidence for preferential uptake by sinusoidal liver cells
    • Kamimoto Y, Horiuchi S, Tanase S, Morino Y. Plasma clearance of intravenously injected aspartate aminotransferase isoenzymes; evidence for preferential uptake by sinusoidal liver cells. Hepatology 1985;5:367-75.
    • (1985) Hepatology , vol.5 , pp. 367-375
    • Kamimoto, Y.1    Horiuchi, S.2    Tanase, S.3    Morino, Y.4
  • 52
    • 0034685935 scopus 로고    scopus 로고
    • Hyaluronan anchoring and regulation on the surface of vascular endothelial cells is mediated through the functionally active form of CD44
    • Nandi A, Estess P, Siegelman MH. Hyaluronan anchoring and regulation on the surface of vascular endothelial cells is mediated through the functionally active form of CD44. J Biol Chem 2000;275:14939-48.
    • (2000) J Biol Chem , vol.275 , pp. 14939-14948
    • Nandi, A.1    Estess, P.2    Siegelman, M.H.3
  • 53
    • 0030003082 scopus 로고    scopus 로고
    • Biosynthesis and degradation of hyaluranon by nonparenchymal liver cells during liver regeneration
    • Vrochides D, Papanikalaou V, Pertoft H, Antoniads AA, Heldin P. Biosynthesis and degradation of hyaluranon by nonparenchymal liver cells during liver regeneration. Hepatology 1996;23:1650-5.
    • (1996) Hepatology , vol.23 , pp. 1650-1655
    • Vrochides, D.1    Papanikalaou, V.2    Pertoft, H.3    Antoniads, A.A.4    Heldin, P.5
  • 54
    • 27544456388 scopus 로고    scopus 로고
    • Mechanisms by which food intake elevated circulating levels of hyaluronan in humans
    • Fraser JR, Gibson PR. Mechanisms by which food intake elevated circulating levels of hyaluronan in humans. J Intern Med 2005;258:460-6.
    • (2005) J Intern Med , vol.258 , pp. 460-466
    • Fraser, J.R.1    Gibson, P.R.2
  • 55
    • 20444424514 scopus 로고    scopus 로고
    • Prediction of hepatic fibrosis in HIV/HCV co-infected patients using serum fibrosis markers: The SHASTA index
    • Kelleher TB, Mehta SH, Bhaskar R, Sulkowski M, Astemborski J, Thomas DL, et al. Prediction of hepatic fibrosis in HIV/HCV co-infected patients using serum fibrosis markers: the SHASTA index. J Hepatol 2005;43:78-84.
    • (2005) J Hepatol , vol.43 , pp. 78-84
    • Kelleher, T.B.1    Mehta, S.H.2    Bhaskar, R.3    Sulkowski, M.4    Astemborski, J.5    Thomas, D.L.6
  • 56
    • 0027158485 scopus 로고
    • Collagens and their abnormalities in a wide spectrum of diseases
    • Kivirikko KI. Collagens and their abnormalities in a wide spectrum of diseases. Ann Med 1993;25:113-26.
    • (1993) Ann Med , vol.25 , pp. 113-126
    • Kivirikko, K.I.1
  • 57
    • 0029879030 scopus 로고    scopus 로고
    • Diagnostic accuracy of hyaluronan and type 3 procollagen amino-terminal peptide serum assays as markers of liver fibrosis in chronic hepatitis C evaluated by ROC curve analysis
    • Guechot J, Laudat A, Loria A, Serfaty L, Poupon R, Giboudeau J. Diagnostic accuracy of hyaluronan and type 3 procollagen amino-terminal peptide serum assays as markers of liver fibrosis in chronic hepatitis C evaluated by ROC curve analysis. Clin Chem 1996;42:558-63.
    • (1996) Clin Chem , vol.42 , pp. 558-563
    • Guechot, J.1    Laudat, A.2    Loria, A.3    Serfaty, L.4    Poupon, R.5    Giboudeau, J.6
  • 58
    • 0026267725 scopus 로고
    • Hepatic fibrosis and its serum markers: A review
    • Gabrielli GB, Corrocher R. Hepatic fibrosis and its serum markers: a review. Dig Dis Sci 1991;9:303-16.
    • (1991) Dig Dis Sci , vol.9 , pp. 303-316
    • Gabrielli, G.B.1    Corrocher, R.2
  • 60
    • 20944437166 scopus 로고    scopus 로고
    • Serum laminin, type IV collagen and hyaluronan as fibrosis markers in non-alcoholic fatty liver disease
    • Santos VN, Leite-Mor MM, Kondo M, Martins JR, Nader H, Lanzoni VP, et al. Serum laminin, type IV collagen and hyaluronan as fibrosis markers in non-alcoholic fatty liver disease. Braz J Med Biol Res 2005;38:747-53.
    • (2005) Braz J Med Biol Res , vol.38 , pp. 747-753
    • Santos, V.N.1    Leite-Mor, M.M.2    Kondo, M.3    Martins, J.R.4    Nader, H.5    Lanzoni, V.P.6
  • 61
    • 21844436061 scopus 로고    scopus 로고
    • Hydroxyproline content of needle biopsies as an objective measure of liver fibrosis: Emphasis on sampling variability
    • Lee HS, Shun CT, Chiou LL, Chen CH, Huang GT, Sheu JC. Hydroxyproline content of needle biopsies as an objective measure of liver fibrosis: emphasis on sampling variability. J Gastroenterol Hepatol 2005;20:1109-14.
    • (2005) J Gastroenterol Hepatol , vol.20 , pp. 1109-1114
    • Lee, H.S.1    Shun, C.T.2    Chiou, L.L.3    Chen, C.H.4    Huang, G.T.5    Sheu, J.C.6
  • 64
    • 0029929470 scopus 로고    scopus 로고
    • Serum type IV collagen in various liver diseases in comparison with serum 7S collagen, laminin, and type III procollagen peptide
    • Hirayama C, Suzuki H, Takada A, Fujisawa K, Tanikawa K, Igarashi S. Serum type IV collagen in various liver diseases in comparison with serum 7S collagen, laminin, and type III procollagen peptide. J Gastroenterol 1996;31:242-8.
    • (1996) J Gastroenterol , vol.31 , pp. 242-248
    • Hirayama, C.1    Suzuki, H.2    Takada, A.3    Fujisawa, K.4    Tanikawa, K.5    Igarashi, S.6
  • 65
    • 0036258828 scopus 로고    scopus 로고
    • Effects of alcohol consumption on 8 circulating markers of liver fibrosis
    • Ponmarenko Y, Anna Leo M, Kroll W, Lieber CS. Effects of alcohol consumption on 8 circulating markers of liver fibrosis. Alcohol Alcohol 2002;37:252-5.
    • (2002) Alcohol Alcohol , vol.37 , pp. 252-255
    • Ponmarenko, Y.1    Anna Leo, M.2    Kroll, W.3    Lieber, C.S.4
  • 66
    • 0037192866 scopus 로고    scopus 로고
    • Inhibition of apoptosis of activated hepatic stellate cells by tissue inhibitor of metalloproteinase-1 is mediated via effects on matrix metalloproteinase inhibition: Implications for reversibility of liver fibrosis
    • Murphy FR, Issa R, Zhou X, Ratnarajah S, Nagase H, Arthur MJ, et al. Inhibition of apoptosis of activated hepatic stellate cells by tissue inhibitor of metalloproteinase-1 is mediated via effects on matrix metalloproteinase inhibition: implications for reversibility of liver fibrosis. J Biol Chem 2002;277:11069-76.
    • (2002) J Biol Chem , vol.277 , pp. 11069-11076
    • Murphy, F.R.1    Issa, R.2    Zhou, X.3    Ratnarajah, S.4    Nagase, H.5    Arthur, M.J.6
  • 69
    • 33746351501 scopus 로고    scopus 로고
    • The mammalian chitinase - like lectin, YKL-40, binds specifically to type 1 collagen and modulates the rate of type 1 collagen fibril formation
    • Bigg HF, Wait R, Rowan AD, Cawston TE. The mammalian chitinase - like lectin, YKL-40, binds specifically to type 1 collagen and modulates the rate of type 1 collagen fibril formation. J Biol Chem 2006;281:210282-95.
    • (2006) J Biol Chem , vol.281 , pp. 210282-210295
    • Bigg, H.F.1    Wait, R.2    Rowan, A.D.3    Cawston, T.E.4
  • 72
    • 39049177340 scopus 로고    scopus 로고
    • Serum fibrosis markers in diagnosing liver fibrosis
    • Liu J, Wang JY, Lu Y. Serum fibrosis markers in diagnosing liver fibrosis. Zhonghua Nei Ke Za Zhi 2006;45:475-7.
    • (2006) Zhonghua Nei Ke Za Zhi , vol.45 , pp. 475-477
    • Liu, J.1    Wang, J.Y.2    Lu, Y.3
  • 73
    • 9644272496 scopus 로고    scopus 로고
    • Evaluation of a panel of non-invasive serum markers to differentiate mild from advanced liver fibrosis in chronic hepatitis C patients
    • Patel K, Gordon SC, Jacobson I, Hezode C, Oh E, Smith KM, et al. Evaluation of a panel of non-invasive serum markers to differentiate mild from advanced liver fibrosis in chronic hepatitis C patients. J Hepatol 2004;41:935-42.
    • (2004) J Hepatol , vol.41 , pp. 935-942
    • Patel, K.1    Gordon, S.C.2    Jacobson, I.3    Hezode, C.4    Oh, E.5    Smith, K.M.6
  • 74
    • 33750366551 scopus 로고    scopus 로고
    • Noninvasive tests for liver fibrosis
    • Mukherjee S, Sorrell MF. Noninvasive tests for liver fibrosis. Semin Liver Dis 2006;26:337-47.
    • (2006) Semin Liver Dis , vol.26 , pp. 337-347
    • Mukherjee, S.1    Sorrell, M.F.2
  • 75
    • 9644279531 scopus 로고    scopus 로고
    • European Liver Fibrosis Group. Serum markers detect the presence of liver fibrosis: A cohort study
    • Rosenberg WM, Voelker M, Thiel R, Becka M, Burt A, Schuppan D, et al. European Liver Fibrosis Group. Serum markers detect the presence of liver fibrosis: a cohort study. Gastroenterology 2004;127:1704-13.
    • (2004) Gastroenterology , vol.127 , pp. 1704-1713
    • Rosenberg, W.M.1    Voelker, M.2    Thiel, R.3    Becka, M.4    Burt, A.5    Schuppan, D.6
  • 76
    • 25444434632 scopus 로고    scopus 로고
    • Hepascore: An accurate validated predictor of liver fibrosis in chronic hepatitis C infection
    • Adams LA, Bulsara M, Rossi E, DeBoer B, Speers D, George J, et al. Hepascore: an accurate validated predictor of liver fibrosis in chronic hepatitis C infection. Clin Chem 2005;51:1867-73.
    • (2005) Clin Chem , vol.51 , pp. 1867-1873
    • Adams, L.A.1    Bulsara, M.2    Rossi, E.3    DeBoer, B.4    Speers, D.5    George, J.6
  • 78
    • 32044431702 scopus 로고    scopus 로고
    • Dysregulated cytokine metabolism, altered hepatic methionine metabolism and proteasome dysfunction in alcoholic liver disease
    • McClain C, Barve S, Joshi-Barve S, Song Z, Deaciuc I, Chen T, et al. Dysregulated cytokine metabolism, altered hepatic methionine metabolism and proteasome dysfunction in alcoholic liver disease. Alcohol Clin Exp Res 2005;29:180S-8S.
    • (2005) Alcohol Clin Exp Res , vol.29
    • McClain, C.1    Barve, S.2    Joshi-Barve, S.3    Song, Z.4    Deaciuc, I.5    Chen, T.6
  • 79
    • 0035552143 scopus 로고    scopus 로고
    • Prediction of progressive liver fibrosis in hepatitis C infection by serum and tissue levels of transforming growth factor-beta
    • Kanzler S, Baumann M, Schirmacher P, Dries V, Bayer E, Gerken G, et al. Prediction of progressive liver fibrosis in hepatitis C infection by serum and tissue levels of transforming growth factor-beta. J Viral Hepatol 2001;8:430-7.
    • (2001) J Viral Hepatol , vol.8 , pp. 430-437
    • Kanzler, S.1    Baumann, M.2    Schirmacher, P.3    Dries, V.4    Bayer, E.5    Gerken, G.6
  • 80
    • 22144446395 scopus 로고    scopus 로고
    • Relationship between serum cytokine levels and histopathological changes of liver in patients with hepatitis B
    • Akpolat N, Yahsi S, Godekmerdan A, Demirbag K, Yalniz M. Relationship between serum cytokine levels and histopathological changes of liver in patients with hepatitis B. World J Gasteroenterol 2005;11:3260-3.
    • (2005) World J Gasteroenterol , vol.11 , pp. 3260-3263
    • Akpolat, N.1    Yahsi, S.2    Godekmerdan, A.3    Demirbag, K.4    Yalniz, M.5
  • 81
    • 33644636469 scopus 로고    scopus 로고
    • Hypoadiponectinemia predicts the severity of hepatic fibrosis and pancreatic Beta-cell dysfunction in nondiabetic nonobese patients with nonalcoholic steatohepatitis
    • Musso G, Gambino R, Biroli G, Carello M, Faga E, Pacini G, et al. Hypoadiponectinemia predicts the severity of hepatic fibrosis and pancreatic Beta-cell dysfunction in nondiabetic nonobese patients with nonalcoholic steatohepatitis. Am J Gastroenterol 2005;100:2438-46.
    • (2005) Am J Gastroenterol , vol.100 , pp. 2438-2446
    • Musso, G.1    Gambino, R.2    Biroli, G.3    Carello, M.4    Faga, E.5    Pacini, G.6
  • 82
    • 24944473560 scopus 로고    scopus 로고
    • Genetic studies to identify hepatic fibrosis genes and SNP's in human populations
    • Day CP. Genetic studies to identify hepatic fibrosis genes and SNP's in human populations. Methods Mol Med 2005;117:315-31.
    • (2005) Methods Mol Med , vol.117 , pp. 315-331
    • Day, C.P.1
  • 83
    • 33644514365 scopus 로고    scopus 로고
    • HLA class I allelic diversity and progression of fibrosis in patients with chronic hepatitis C
    • Patel K, Norris S, Lebeck L, Feng A, Clare M, Pianko S, et al. HLA class I allelic diversity and progression of fibrosis in patients with chronic hepatitis C. Hepatology 2006;43:241-9.
    • (2006) Hepatology , vol.43 , pp. 241-249
    • Patel, K.1    Norris, S.2    Lebeck, L.3    Feng, A.4    Clare, M.5    Pianko, S.6
  • 84
    • 0037371468 scopus 로고    scopus 로고
    • Genetic polymorphism and the progression of liver fibrosis: A critical appraisal
    • Bataller R, North KE, Brenner Da. Genetic polymorphism and the progression of liver fibrosis: a critical appraisal. Hepatology 2003;37:493-503.
    • (2003) Hepatology , vol.37 , pp. 493-503
    • Bataller, R.1    North, K.E.2    Brenner, D.3
  • 85
    • 33645986652 scopus 로고    scopus 로고
    • Progression of fibrosis in hepatitis C with and without schistosomiasis: Correlation with serum markers of fibrosis
    • Kamal SM, Turner B, He Q, Rasenack J, Bianchi L, Al Tawil A, et al. Progression of fibrosis in hepatitis C with and without schistosomiasis: correlation with serum markers of fibrosis. Hepatology 2006;43:771-9.
    • (2006) Hepatology , vol.43 , pp. 771-779
    • Kamal, S.M.1    Turner, B.2    He, Q.3    Rasenack, J.4    Bianchi, L.5    Al Tawil, A.6
  • 86
  • 88
    • 1842504404 scopus 로고    scopus 로고
    • Real-time TaqMan PCR detection and quantitation of HBV genotypes A-G with the use of an internal quantitation standard
    • Weiss J, Wu H, Farrenkopf B, Schultz T, Song G, Shah S, et al. Real-time TaqMan PCR detection and quantitation of HBV genotypes A-G with the use of an internal quantitation standard. J Clin Virol 2004;30:86-93.
    • (2004) J Clin Virol , vol.30 , pp. 86-93
    • Weiss, J.1    Wu, H.2    Farrenkopf, B.3    Schultz, T.4    Song, G.5    Shah, S.6
  • 89
    • 33748929265 scopus 로고    scopus 로고
    • Peginterferon alpha-2b plus adefovir induce strong cccDNA decline and HBsAg reduction in patients with chronic hepatitis B
    • Wursthorn K, Lutgehetmann M, Dandri M, Volz T, Buggisch P, Zollner B, et al. Peginterferon alpha-2b plus adefovir induce strong cccDNA decline and HBsAg reduction in patients with chronic hepatitis B. Hepatology 2006;44:675-84.
    • (2006) Hepatology , vol.44 , pp. 675-684
    • Wursthorn, K.1    Lutgehetmann, M.2    Dandri, M.3    Volz, T.4    Buggisch, P.5    Zollner, B.6
  • 90
    • 19944428132 scopus 로고    scopus 로고
    • HBV 99-01 Study Group; Rotterdam Foundation for Liver Research. Pegylated interferon alfa-2b alone or in combination with lamivudine for HbeAg-positive chronic hepatitis B: A radomised trial
    • Janssen HL, van Zonneveld M, Senturk H, Zeuzem S, Akarca US, Cakaloglu Y, et al. HBV 99-01 Study Group; Rotterdam Foundation for Liver Research. Pegylated interferon alfa-2b alone or in combination with lamivudine for HbeAg-positive chronic hepatitis B: a radomised trial. Lancet 2005;365:123-9.
    • (2005) Lancet , vol.365 , pp. 123-129
    • Janssen, H.L.1    van Zonneveld, M.2    Senturk, H.3    Zeuzem, S.4    Akarca, U.S.5    Cakaloglu, Y.6
  • 92
    • 0033761078 scopus 로고    scopus 로고
    • Early detection of viral resistance by determination of hepatitis B virus polymerase mutations in patients treated by lamivudine for chronic hepatitis B
    • Nafa S, Ahmed S, Tavan D, Pichoud C, Berby F, Stuyver L, et al. Early detection of viral resistance by determination of hepatitis B virus polymerase mutations in patients treated by lamivudine for chronic hepatitis B. Hepatology 2000;32:1078-88.
    • (2000) Hepatology , vol.32 , pp. 1078-1088
    • Nafa, S.1    Ahmed, S.2    Tavan, D.3    Pichoud, C.4    Berby, F.5    Stuyver, L.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.