Most acute myeloid leukaemia patients with intermediate mutant FLT3/ITD levels do not have detectable bi-allelic disease, indicating that heterozygous disease alone is associated with an adverse outcome

British Journal of Haematology

Volumn 142, Issue 3, 2008, Pages 423-426

  Green, Claire ^a   Linch, David C ^a   Gale, Rosemary E ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

Bi allelic disease; FLT3 internal tandem duplication; Uniparental disomy

Indexed keywords

CD135 ANTIGEN;

ACUTE GRANULOCYTIC LEUKEMIA; ARTICLE; CELL MUTANT; DISEASE ASSOCIATION; GENE DUPLICATION; GENE MUTATION; GENETIC ANALYSIS; HETEROZYGOSITY; HOMOZYGOSITY; HUMAN; PRIORITY JOURNAL; PROGNOSIS; RELAPSE; SINGLE NUCLEOTIDE POLYMORPHISM; WILD TYPE;

ALLELES; CASE-CONTROL STUDIES; FMS-LIKE TYROSINE KINASE 3; GENE DUPLICATION; HETEROZYGOTE; HOMOZYGOTE; HUMANS; IN SITU HYBRIDIZATION, FLUORESCENCE; LEUKEMIA, MYELOID, ACUTE; PROGNOSIS; RECURRENCE; TANDEM REPEAT SEQUENCES;

EID: 46949095907     PISSN: 00071048     EISSN: 13652141     Source Type: Journal    
DOI: 10.1111/j.1365-2141.2008.07196.x     Document Type: Article

References (7)

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