Thrombin-induced expression of endothelial CX3CL1 potentiates monocyte CCL2 production and transendothelial migration

Journal of Leukocyte Biology

Volumn 84, Issue 1, 2008, Pages 215-223

  Popovic, Milan ^a   Laumonnier, Yves ^a   Burysek, Ladislav ^a   Syrovets, Tatiana ^a   Simmet, Thomas ^a  

^a UNIVERSITY OF ULM   (Germany)

Author keywords

Chemokine; Coculture; HUVEC; Mono Mac 6; Protease activated receptor 1

Indexed keywords

ACETY 11 KETO BETA BOSWELLIC ACID; FRACTALKINE; I KAPPA B KINASE; I KAPPA B KINASE INHIBITOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MONOCYTE CHEMOTACTIC PROTEIN 1; PROTEINASE ACTIVATED RECEPTOR 1; RECEPTOR BLOCKING AGENT; SCH 79797; THROMBIN;

ARTICLE; CELL FUNCTION; CELL MIGRATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; ENDOTHELIUM CELL; ENZYME INHIBITION; FLOW CYTOMETRY; GEL MOBILITY SHIFT ASSAY; HUMAN; HUMAN CELL; MONOCYTE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

CELL LINE; CELL MOVEMENT; CHEMOKINE CCL2; CHEMOKINE CX3CL1; CHEMOTAXIS; COCULTURE TECHNIQUES; ENDOTHELIAL CELLS; GENE EXPRESSION REGULATION; HUMANS; MONOCYTES; NF-KAPPA B; RECEPTOR, PAR-1; RNA, MESSENGER; THROMBIN; UMBILICAL VEINS;

EID: 46949095902     PISSN: 07415400     EISSN: None     Source Type: Journal    
DOI: 10.1189/jlb.0907652     Document Type: Article

References (45)

1. Weber, C. (2007) Chemokines take center stage in vascular biology. Thromb. Haemost. 97, 685-687.
2. Zlotnik, A., Yoshie, O. (2000) Chemokines: a new classification system and their role in immunity. Immunity 12, 121-127.
3. Bazan, J. F., Bacon, K. B., Hardiman, G., Wang, W., Soo, K., Rossi, D., Greaves, D. R., Zlotnik, A., Schall, T. J. (1997) A new class of membrane-bound chemokine with a CX3C motif. Nature 385, 640-644.
4. Ludwig, A., Weber, C. (2007) Transmembrane chemokines: versatile "special agents" in vascular inflammation. Thromb. Haemost. 97, 694-703.
5. Garton, K. J., Gough, P. J., Blobel, C. P., Murphy, G., Greaves, D. R., Dempsey, P. J., Raines, E. W. (2001) Tumor necrosis factor-α-converting enzyme (ADAM17) mediates the cleavage and shedding of fractalkine (CX3CL1). J. Biol. Chem. 276, 37993-38001.
6. Hundhausen, C., Misztela, D., Berkhout, T. A., Broadway, N., Saftig, P., Reiss, K., Hartmann, D., Fahrenholz, F., Postina, R., Matthews, V., Kallen, K. J., Rose-John, S., Ludwig, A. (2003) The disintegrin-like metalloproteinase ADAM10 is involved in constitutive cleavage of CX3CL1 (fractalkine) and regulates CX3CL1-mediated cell-cell adhesion. Blood 102, 1186-1195.
7. Umehara, H., Bloom, E. T., Okazaki, T., Nagano, Y., Yoshie, O., Imai, T. (2004) Fractalkine in vascular biology: from basic research to clinical disease. Arterioscler. Thromb. Vasc. Biol. 24, 34-40.
8. Greaves, D. R., Hakkinen, T., Lucas, A. D., Liddiard, K., Jones, E., Quinn, C. M., Senaratne, J., Green, F. R., Tyson, K., Boyle, J., Shanahan, C., Weissberg, P. L., Gordon, S., Yla-Hertualla, S. (2001) Linked chromosome 16q13 chemokines, macrophage-derived chemokine, fractalkine, and thymus- and activation-regulated chemokine, are expressed in human atherosclerotic lesions. Arterioscler. Thromb. Vasc. Biol. 21, 923-929.
9. Wong, B. W., Wong, D., McManus, B. M. (2002) Characterization of fractalkine (CX3CL1) and CX3CR1 in human coronary arteries with native atherosclerosis, diabetes mellitus, and transplant vascular disease. Cardiovasc. Pathol. 11, 332-338.
10. Harrison, J. K., Jiang, Y., Wees, E. A., Salafranca, M. N., Liang, H. X., Feng, L., Belardinelli, L. (1999) Inflammatory agents regulate in vivo expression of fractalkine in endothelial cells of the rat heart. J. Leukoc. Biol. 66, 937-944.
11. Fraticelli, P., Sironi, M., Bianchi, G., D'Ambrosio, D., Albanesi, C., Stoppacciaro, A., Chieppa, M., Allavena, P., Ruco, L., Girolomoni, G., Sinigaglia, F., Vecchi, A., Mantovani, A. (2001) Fractalkine (CX3CL1) as an amplification circuit of polarized Th1 responses. J. Clin. Invest. 107, 1173-1181.
12. Brueckmann, M., Nahrup, A. S., Lang, S., Bertsch, T., Fukudome, K., Liebe, V., Kaden, J. J., Hoffmann, U., Borggrefe, M., Huhle, G. (2006) Recombinant human activated protein C upregulates the release of soluble fractalkine from human endothelial cells. Br. J. Haematol. 133, 550-557.
13. Garcia, G. E., Xia, Y., Chen, S., Wang, Y., Ye, R. D., Harrison, J. K., Bacon, K. B., Zerwes, H. G., Feng, L. (2000) NF-κB-dependent fractalkine induction in rat aortic endothelial cells stimulated by IL-1β, TNF-α, and LPS. J. Leukoc. Biol. 67, 577-584.
14. Bunnett, N. W. (2006) Protease-activated receptors: how proteases signal to cells to cause inflammation and pain. Semin. Thromb. Hemost. 32 (Suppl. 1), 39-48.
15. Coughlin, S. R. (2005) Protease-activated receptors in hemostasis, thrombosis and vascular biology. J. Thromb. Haemost. 3, 1800-1814.
16. Minami, T., Sugiyama, A., Wu, S. Q., Abid, R., Kodama, T., Aird, W. C. (2004) Thrombin and phenotypic modulation of the endothelium. Arterioscler. Thromb. Vasc. Biol. 24, 41-53.
17. Laumonnier, Y., Syrovets, T., Burysek, L., Simmet, T. (2006) Identification of the annexin A2 heterotetramer as a receptor for the plasmin-induced signaling in human peripheral monocytes. Blood 107, 3342-3349.
18. Laumonnier, Y., Nadaud, S., Agrapart, M., Soubrier, F. (2000) Characterization of an upstream enhancer region in the promoter of the human endothelial nitric-oxide synthase gene. J. Biol. Chem. 275, 40732-40741.
19. Yoshikawa, M., Nakajima, T., Matsumoto, K., Okada, N., Tsukidate, T., Iida, M., Otori, N., Haruna, S., Moriyama, H., Imai, T., Saito, H. (2004) TNF-α and IL-4 regulate expression of fractalkine (CX3CL1) as a membrane-anchored proadhesive protein and soluble chemotactic peptide on human fibroblasts. FEBS Lett. 561, 105-110.
20. Syrovets, T., Büchele, B., Krauss, C., Laumonnier, Y., Simmet, T. (2005) Acetyl-boswellic acids inhibit lipopolysaccharide-mediated TNF-α induction in monocytes by direct interaction with IκB kinases. J. Immunol. 174, 498-506.
21. Ahn, H. S., Foster, C., Boykow, G., Stamford, A., Manna, M., Graziano, M. (2000) Inhibition of cellular action of thrombin by N3-cyclopropyl-7-[[4-(1- methylethyl)phenyl]methyl]-7H-pyrrolo[3, 2-f]quinazoline-1,3-diamine (SCH 79797), a nonpeptide thrombin receptor antagonist. Biochem. Pharmacol. 60, 1425-1434.
22. Chavakis, T., Athanasopoulos, A., Rhee, J. S., Orlova, V., Schmidt-Woll, T., Bierhaus, A., May, A. E., Celik, I., Nawroth, P. P., Preissner, K. T. (2005) Angiostatin is a novel anti-inflammatory factor by inhibiting leukocyte recruitment. Blood 105, 1036-1043.
23. Syrovets, T., Gschwend, J. E., Büchele, B., Laumonnier, Y., Zugmaier, W., Genze, F., Simmet, T. (2005) Inhibition of IκB kinase activity by acetylboswellic acids promotes apoptosis in androgen-independent PC-3 prostate cancer cells in vitro and in vivo. J. Biol. Chem. 280, 6170-6180.
24. Brockman, J. A., Scherer, D. C., McKinsey, T. A., Hall, S. M., Qi, X., Lee, W. Y., Ballard, D. W. (1995) Coupling of a signal response domain in IκBα to multiple pathways for NF-κB activation. Mol. Cell. Biol. 15, 2809-2818.
25. Lukacs, N. W., Strieter, R. M., Elner, V., Evanoff, H. L., Burdick, M. D., Kunkel, S. L. (1995) Production of chemokines, interleukin-8 and monocyte chemoattractant protein-1, during monocyte: endothelial cell interactions. Blood 86, 2767-2773.
26. + monocytes. J. Exp. Med. 197, 1701-1707.
27. Goda, S., Imai, T., Yoshie, O., Yoneda, O., Inoue, H., Nagano, Y., Okazaki, T., Imai, H., Bloom, E. T., Domae, N., Umehara, H. (2000) CX3C-chemokine, fractalkine-enhanced adhesion of THP-1 cells to endothelial cells through integrin-dependent and -independent mechanisms. J. Immunol. 164, 4313-4320.
28. Vitale, S., Schmid-Alliana, A., Breuil, V., Pomeranz, M., Millet, M. A., Rossi, B., Schmid-Antomarchi, H. (2004) Soluble fractalkine prevents monocyte chemoattractant protein-1-induced monocyte migration via inhibition of stress-activated protein kinase 2/p38 and matrix metalloproteinase activities. J. Immunol. 172, 585-592.
29. Bretschneider, E., Spanbroek, R., Lotzer, K., Habenicht, A. J., Schrör, K. (2003) Evidence for functionally active protease-activated receptor-3 (PAR-3) in human vascular smooth muscle cells. Thromb. Haemost. 90, 704-709.
30. Bzowska, M., Jura, N., Lassak, A., Black, R. A., Bereta, J. (2004) Tumor necrosis factor-α stimulates expression of TNF-α converting enzyme in endothelial cells. Eur. J. Biochem. 271, 2808-2820.
31. Kaplanski, G., Fabrigoule, M., Boulay, V., Dinarello, C. A., Bongrand, P., Kaplanski, S., Farnarier, C. (1997) Thrombin induces endothelial type II activation in vitro: IL-1 and TNF-α-independent IL-8 secretion and E-selectin expression. J. Immunol. 158, 5435-5441.
32. Sugama, Y., Tiruppathi, C., Offakidevi, K., Andersen, T. T., Fenton II, J. W., Malik, A. B. (1992) Thrombin-induced expression of endothelial P-selectin and intercellular adhesion molecule-1: a mechanism for stabilizing neutrophil adhesion. J. Cell Biol. 119, 935-944.
33. Haskell, C. A., Cleary, M. D., Charo, I. F. (1999) Molecular uncoupling of fractalkine-mediated cell adhesion and signal transduction. Rapid flow arrest of CX3CR1-expressing cells is independent of G-protein activation. J. Biol. Chem. 274, 10053-10058.
34. Gerszten, R. E., Garcia-Zepeda, E. A., Lim, Y. C., Yoshida, M., Ding, H. A., Gimbrone Jr., M. A., Luster, A. D., Luscinskas, F. W., Rosenzweig, A. (1999) MCP-1 and IL-8 trigger firm adhesion of monocytes to vascular endothelium under flow conditions. Nature 398, 718-723.
35. Green, S. R., Han, K. H., Chen, Y., Almazan, F., Charo, I. F., Miller, Y. I., Quehenberger, O. (2006) The CC chemokine MCP-1 stimulates surface expression of CX3CR1 and enhances the adhesion of monocytes to fractalkine/ CX3CL1 via p38 MAPK. J. Immunol. 176, 7412-7420.
36. Braunersreuther, V., Mach, F., Steffens, S. (2007) The specific role of chemokines in atherosclerosis. Thromb. Haemost. 97, 714-721.
37. Hordijk, P. L. (2006) Endothelial signaling events during leukocyte transmigration. FEBS J. 273, 4408-4415.
38. Chakraborty, A., Brooks, H., Zhang, P., Smith, W., McReynolds, M. R., Hoying, J. B., Bick, R., Truong, L., Poindexter, B., Lan, H., Elbjeirami, W., Sheikh-Hamad, D. (2007) Stanniocalcin-1 regulates endothelial gene expression and modulates transendothelial migration of leukocytes. Am. J. Physiol. Renal Physiol. 292, F895-F904.
39. Matias-Roman, S., Galvez, B. G., Genis, L., Yanez-Mo, M., de la Rosa, G., Sanchez-Mateos, P., Sanchez-Madrid, F., Arroyo, A. G. (2005) Membrane type 1-matrix metalloproteinase is involved in migration of human monocytes and is regulated through their interaction with fibronectin or endothelium. Blood 105, 3956-3964.
40. Bea, F., Kreuzer, J., Preusch, M., Schaab, S., Isermann, B., Rosenfeld, M. E., Katus, H., Blessing, E. (2006) Melagatran reduces advanced atherosclerotic lesion size and may promote plaque stability in apolipoprotein E-deficient mice. Arterioscler. Thromb. Vasc. Biol. 26, 2787-2792.
41. -/- mice reveals a role for fractalkine in atherogenesis. J. Clin. Invest. 111, 333-340.
42. Combadiere, C., Potteaux, S., Gao, J. L., Esposito, B., Casanova, S., Lee, E. J., Debre, P., Tedgui, A., Murphy, P. M., Mallat, Z. (2003) Decreased atherosclerotic lesion formation in CX3CR1/apolipoprotein E double knockout mice. Circulation 107, 1009-1016.
43. -/- mice: evidence for independent chemokine functions in atherogenesis. Circulation 117, 1642-1648.
44. Tacke, F., Alvarez, D., Kaplan, T. J., Jakubzick, C., Spanbroek, R., Llodra, J., Garin, A., Liu, J., Mack, M., van Rooijen, N., Lira, S. A., Habenicht, A. J., Randolph, G. J. (2007) Monocyte subsets differentially employ CCR2, CCR5, and CX3CR1 to accumulate within atherosclerotic plaques. J. Clin. Invest. 117, 185-194.
45. Auffray, C., Fogg, D., Garfa, M., Elain, G., Join-Lambert, O., Kayal, S., Sarnacki, S., Cumano, A., Lauvau, G., Geissmann, F. (2007) Monitoring of blood vessels and tissues by a population of monocytes with patrolling behavior. Science 317, 666-670.