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Volumn 124, Issue 4, 2008, Pages 553-561

Interleukin-12 is necessary for the priming of CD4+ T cells required during the elicitation of HIV-1 gp120-specific cytotoxic T-lymphocyte function

Author keywords

Cytokine; Cytotoxic T lymphocytes; gp120; Human immunodeficiency virus 1; Interleukin 12

Indexed keywords

COMPLEMENTARY DNA; DNA; GAMMA INTERFERON; GLYCOPROTEIN GP 120; INTERLEUKIN 12;

EID: 46949088296     PISSN: 00192805     EISSN: 13652567     Source Type: Journal    
DOI: 10.1111/j.1365-2567.2008.02809.x     Document Type: Article
Times cited : (12)

References (46)
  • 2
    • 0029958159 scopus 로고    scopus 로고
    • Fas-mediated apoptosis
    • Nagata S. Fas-mediated apoptosis. Adv Exp Med Biol 1996 406 : 119 24.
    • (1996) Adv Exp Med Biol , vol.406 , pp. 119-24
    • Nagata, S.1
  • 3
    • 0028258577 scopus 로고
    • Cytotoxic lymphocytes require granzyme B for the rapid induction of DNA fragmentation and apoptosis in allogeneic target cells
    • Heusel JW, Wesselschmidt RL, Shresta S, Russell JH, Ley TJ. Cytotoxic lymphocytes require granzyme B for the rapid induction of DNA fragmentation and apoptosis in allogeneic target cells. Cell 1994 76 : 977 87.
    • (1994) Cell , vol.76 , pp. 977-87
    • Heusel, J.W.1    Wesselschmidt, R.L.2    Shresta, S.3    Russell, J.H.4    Ley, T.J.5
  • 4
    • 0036779576 scopus 로고    scopus 로고
    • Functional significance of the perforin/granzyme cell death pathway
    • Trapani JA, Smyth MJ. Functional significance of the perforin/granzyme cell death pathway. Nat Rev Immunol 2002 2 : 735 47.
    • (2002) Nat Rev Immunol , vol.2 , pp. 735-47
    • Trapani, J.A.1    Smyth, M.J.2
  • 5
    • 0141629530 scopus 로고    scopus 로고
    • Granzyme B: Pro-apoptotic, antiviral and antitumor functions
    • Trapani JA, Sutton VR. Granzyme B: pro-apoptotic, antiviral and antitumor functions. Curr Opin Immunol 2003 15 : 533 43.
    • (2003) Curr Opin Immunol , vol.15 , pp. 533-43
    • Trapani, J.A.1    Sutton, V.R.2
  • 7
    • 0030630914 scopus 로고    scopus 로고
    • Cytokines and cytokine therapies in HIV infection
    • Valdez H, Lederman MM. Cytokines and cytokine therapies in HIV infection. AIDS Clin Rev 1997 187 : 187 228.
    • (1997) AIDS Clin Rev , vol.187 , pp. 187-228
    • Valdez, H.1    Lederman, M.M.2
  • 8
    • 0021646280 scopus 로고
    • Noninfectious cofactors in susceptibility to AIDS: Possible contributions of semen, HLA alloantigens, and lack of natural resistance
    • Shearer GM, Levy RB. Noninfectious cofactors in susceptibility to AIDS: possible contributions of semen, HLA alloantigens, and lack of natural resistance. Ann N Y Acad Sci 1984 437 : 49 57.
    • (1984) Ann N Y Acad Sci , vol.437 , pp. 49-57
    • Shearer, G.M.1    Levy, R.B.2
  • 9
    • 0029836425 scopus 로고    scopus 로고
    • Type 1 and type 2 cytokine profiles in children exposed to or infected with vertically transmitted human immunodeficiency virus
    • Lee BN, Lu JG, Kline MW, Paul M, Doyle M, Kozinetz C, Shearer WT, Reuben JM. Type 1 and type 2 cytokine profiles in children exposed to or infected with vertically transmitted human immunodeficiency virus. Clin Diagn Lab Immunol 1996 3 : 493 9.
    • (1996) Clin Diagn Lab Immunol , vol.3 , pp. 493-9
    • Lee, B.N.1    Lu, J.G.2    Kline, M.W.3    Paul, M.4    Doyle, M.5    Kozinetz, C.6    Shearer, W.T.7    Reuben, J.M.8
  • 12
    • 0038792209 scopus 로고    scopus 로고
    • CD40 and dendritic cell function
    • O'Sullivan B, Thomas R. CD40 and dendritic cell function. Crit Rev Immunol 2003 23 : 83 107.
    • (2003) Crit Rev Immunol , vol.23 , pp. 83-107
    • O'Sullivan, B.1    Thomas, R.2
  • 13
    • 0032428793 scopus 로고    scopus 로고
    • Protein levels of interleukin-12 p70 holomer, its p40 chain and interferon-gamma during advancing HIV infection
    • Rockstroh JK, Kruezer KA, Sauerbruch T, Spengler U. Protein levels of interleukin-12 p70 holomer, its p40 chain and interferon-gamma during advancing HIV infection. J Infect 1998 37 : 282 6.
    • (1998) J Infect , vol.37 , pp. 282-6
    • Rockstroh, J.K.1    Kruezer, K.A.2    Sauerbruch, T.3    Spengler, U.4
  • 15
    • 0033179165 scopus 로고    scopus 로고
    • The interleukin-12-mediated pathway of immune events is dysfunctional in human immunodeficiency virus-infected individuals
    • Marshall JD, Chehimi J, Gri G, Kostman JR, Montaner LJ, Trinchieri G. The interleukin-12-mediated pathway of immune events is dysfunctional in human immunodeficiency virus-infected individuals. Blood 1999 94 : 1003 11.
    • (1999) Blood , vol.94 , pp. 1003-11
    • Marshall, J.D.1    Chehimi, J.2    Gri, G.3    Kostman, J.R.4    Montaner, L.J.5    Trinchieri, G.6
  • 16
    • 0030971242 scopus 로고    scopus 로고
    • Demonstration of the Th1 to Th2 cytokine shift during the course of HIV-1 infection using cytoplasmic cytokine detection on single cell level by flow cytometry
    • Klein SA, Dobmeyer JM, Dobmeyer TS, Pape M, Ottmann OG, Helm EB, Hoelzer D, Rossol R. Demonstration of the Th1 to Th2 cytokine shift during the course of HIV-1 infection using cytoplasmic cytokine detection on single cell level by flow cytometry. AIDS 1997 11 : 1111 8.
    • (1997) AIDS , vol.11 , pp. 1111-8
    • Klein, S.A.1    Dobmeyer, J.M.2    Dobmeyer, T.S.3    Pape, M.4    Ottmann, O.G.5    Helm, E.B.6    Hoelzer, D.7    Rossol, R.8
  • 17
    • 0033556145 scopus 로고    scopus 로고
    • IL-12 is not required for induction of type 1 cytokine responses in viral infections
    • Oxenius A, Karrer U, Zinkernagel RM, Hengartner H. IL-12 is not required for induction of type 1 cytokine responses in viral infections. J Immunol 1999 162 : 965 73.
    • (1999) J Immunol , vol.162 , pp. 965-73
    • Oxenius, A.1    Karrer, U.2    Zinkernagel, R.M.3    Hengartner, H.4
  • 18
    • 0030790652 scopus 로고    scopus 로고
    • Interleukin 12 (IL-12) is crucial to the development of protective immunity in mice intravenously infected with Mycobacterium tuberculosis
    • Cooper AM, Magram J, Ferrante J, Orme IM. Interleukin 12 (IL-12) is crucial to the development of protective immunity in mice intravenously infected with Mycobacterium tuberculosis. J Exp Med 1997 186 : 39 45.
    • (1997) J Exp Med , vol.186 , pp. 39-45
    • Cooper, A.M.1    Magram, J.2    Ferrante, J.3    Orme, I.M.4
  • 19
    • 33746651142 scopus 로고    scopus 로고
    • Polyvalent HIV-1 Env vaccine formulations delivered by the DNA priming plus protein boosting approach are effective in generating neutralizing antibodies against primary human immunodeficiency virus type 1 isolates from subtypes A, B, C, D and e
    • Wang S, Pal R, Mascola JR et al. Polyvalent HIV-1 Env vaccine formulations delivered by the DNA priming plus protein boosting approach are effective in generating neutralizing antibodies against primary human immunodeficiency virus type 1 isolates from subtypes A, B, C, D and E. Virology 2006 350 : 34 47.
    • (2006) Virology , vol.350 , pp. 34-47
    • Wang, S.1    Pal, R.2    Mascola, J.R.3
  • 21
    • 0032889281 scopus 로고    scopus 로고
    • Full-length human immunodeficiency virus type 1 genomes from subtype C-infected seroconverters in India, with evidence of intersubtype recombination
    • Lole KS, Bollinger RC, Paranjape RS et al. Full-length human immunodeficiency virus type 1 genomes from subtype C-infected seroconverters in India, with evidence of intersubtype recombination. J Virol 1999 73 : 152 60.
    • (1999) J Virol , vol.73 , pp. 152-60
    • Lole, K.S.1    Bollinger, R.C.2    Paranjape, R.S.3
  • 23
    • 0028955229 scopus 로고
    • Expression and purification of glutathione S-transferase-tagged HIV-1 gp120: No evidence of an interaction with CD26
    • Wang YH, Davies AH, Jones IM. Expression and purification of glutathione S-transferase-tagged HIV-1 gp120: no evidence of an interaction with CD26. Virology 1995 208 : 142 6.
    • (1995) Virology , vol.208 , pp. 142-6
    • Wang, Y.H.1    Davies, A.H.2    Jones, I.M.3
  • 24
    • 0002337605 scopus 로고
    • Preparation of mouse cell suspension
    • Michell, B.E., Shiigi, S.M. (. eds). In: New York: W.H. Freeman and company
    • Michell BE, Shiigi SM (eds). Preparation of mouse cell suspension. In : Selected Method in Cellular Immunology. New York : W.H. Freeman and company, 1980 : 23 4.
    • (1980) Selected Method in Cellular Immunology. , pp. 23-4
  • 25
    • 0025792001 scopus 로고
    • The JAM test. a simple assay for DNA fragmentation and cell death
    • Matzinger P. The JAM test. A simple assay for DNA fragmentation and cell death. J Immunol Methods 1991 145 : 185 92.
    • (1991) J Immunol Methods , vol.145 , pp. 185-92
    • Matzinger, P.1
  • 26
    • 12344301910 scopus 로고    scopus 로고
    • Decreased perforin and granzyme B expression in senescent HIV-1-specific cytotoxic T lymphocytes
    • Ang OO, Lin H, Dagarag M, Ng HL, Effros RB, Uittenbogaart CH. Decreased perforin and granzyme B expression in senescent HIV-1-specific cytotoxic T lymphocytes. Virology 2005 332 : 16 9.
    • (2005) Virology , vol.332 , pp. 16-9
    • Ang, O.O.1    Lin, H.2    Dagarag, M.3    Ng, H.L.4    Effros, R.B.5    Uittenbogaart, C.H.6
  • 27
    • 0034600786 scopus 로고    scopus 로고
    • + T cells produce antiviral cytokines but are impaired in cytolytic function
    • + T cells produce antiviral cytokines but are impaired in cytolytic function. J Exp Med 2000 192 : 63 75.
    • (2000) J Exp Med , vol.192 , pp. 63-75
    • Appay, V.1    Nixon, D.F.2    Donahoe, S.M.3
  • 28
    • 0035928858 scopus 로고    scopus 로고
    • The role of T cell help for anti-viral CTL responses
    • Wodarz D, Jansen VA. The role of T cell help for anti-viral CTL responses. J Theor Biol 2001 211 : 419 32.
    • (2001) J Theor Biol , vol.211 , pp. 419-32
    • Wodarz, D.1    Jansen, V.A.2
  • 31
    • 0030055867 scopus 로고    scopus 로고
    • Molecular analysis of decreased interleukin-12 production in persons infected with human immunodeficiency virus
    • Chougnet C, Wynn TA, Clerici M et al. Molecular analysis of decreased interleukin-12 production in persons infected with human immunodeficiency virus. J Infect Dis 1996 174 : 46 53.
    • (1996) J Infect Dis , vol.174 , pp. 46-53
    • Chougnet, C.1    Wynn, T.A.2    Clerici, M.3
  • 33
    • 0033564305 scopus 로고    scopus 로고
    • IL-13 and IFN-γ secretion by activated T cells in HIV-1 infection associated with viral suppression and a lack of disease progression
    • Bailer RT, Holloway A, Sun J, Margolick JB, Martin M, Kostman J, Montaner LJ. IL-13 and IFN-γ secretion by activated T cells in HIV-1 infection associated with viral suppression and a lack of disease progression. J Immunol 1999 162 : 7534 42.
    • (1999) J Immunol , vol.162 , pp. 7534-42
    • Bailer, R.T.1    Holloway, A.2    Sun, J.3    Margolick, J.B.4    Martin, M.5    Kostman, J.6    Montaner, L.J.7
  • 34
    • 0036530017 scopus 로고    scopus 로고
    • Persistent numbers of tetramer+ CD8(+) T cells, but loss of interferon-gamma+ HIV-specific T cells during progression to AIDS
    • Kostense S, Vandenberghe K, Joling J, Van Baarle D, Nanlohy N, Manting E, Miedema F. Persistent numbers of tetramer+ CD8(+) T cells, but loss of interferon-gamma+ HIV-specific T cells during progression to AIDS. Blood 2002 99 : 2505 11.
    • (2002) Blood , vol.99 , pp. 2505-11
    • Kostense, S.1    Vandenberghe, K.2    Joling, J.3    Van Baarle, D.4    Nanlohy, N.5    Manting, E.6    Miedema, F.7
  • 35
    • 0033811377 scopus 로고    scopus 로고
    • Therapeutic immunization of HIV-infected chimpanzees using HIV-1 plasmid antigens and interleukin-12 expressing plasmids
    • Boyer JD, Cohen AD, Ugen KE et al. Therapeutic immunization of HIV-infected chimpanzees using HIV-1 plasmid antigens and interleukin-12 expressing plasmids. AIDS 2000 14 : 1515 22.
    • (2000) AIDS , vol.14 , pp. 1515-22
    • Boyer, J.D.1    Cohen, A.D.2    Ugen, K.E.3
  • 36
    • 0035043482 scopus 로고    scopus 로고
    • + T cells from late stage patients on prolonged antiretroviral therapy by stimulation in vitro with HIV-1 protein loaded dendritic cells
    • + T cells from late stage patients on prolonged antiretroviral therapy by stimulation in vitro with HIV-1 protein loaded dendritic cells. J Virol 2001 75 : 4413 9.
    • (2001) J Virol , vol.75 , pp. 4413-9
    • Fan, Z.1    Huang, X.L.2    Borowski, L.3    Mellors, J.W.4    Rinaldo Jr., C.R.5
  • 37
    • 0032506241 scopus 로고    scopus 로고
    • Inhibition of interferon gamma induced interleukin 12 production: A potential mechanism for the anti-inflammatory activities of tumor necrosis factor
    • Hodge-Dufour J, Marino MW, Horton MR. et al. Inhibition of interferon gamma induced interleukin 12 production: a potential mechanism for the anti-inflammatory activities of tumor necrosis factor. Proc Natl Acad Sci U S A 1998 95 : 13806 11.
    • (1998) Proc Natl Acad Sci U S a , vol.95 , pp. 13806-11
    • Hodge-Dufour, J.1    Marino, M.W.2    Horton, M.R.3
  • 39
    • 0030460164 scopus 로고    scopus 로고
    • Interleukin-12 production by dendritic cells. the role of CD40-CD40L interactions in Th1 T-cell responses
    • Kelsall BL, Stuber E, Neurath M, Strober W. Interleukin-12 production by dendritic cells. The role of CD40-CD40L interactions in Th1 T-cell responses. Ann N Y Acad Sci 1996 795 : 116 26.
    • (1996) Ann N Y Acad Sci , vol.795 , pp. 116-26
    • Kelsall, B.L.1    Stuber, E.2    Neurath, M.3    Strober, W.4
  • 40
    • 0030029222 scopus 로고    scopus 로고
    • Blocking the CD40L-CD40 interaction in vivo specifically prevents the priming of T helper 1 cells through the inhibition of interleukin 12 secretion
    • Stuber E, Strober W, Neurath M. Blocking the CD40L-CD40 interaction in vivo specifically prevents the priming of T helper 1 cells through the inhibition of interleukin 12 secretion. J Exp Med 1996 183 : 693 8.
    • (1996) J Exp Med , vol.183 , pp. 693-8
    • Stuber, E.1    Strober, W.2    Neurath, M.3
  • 43
    • 0033805788 scopus 로고    scopus 로고
    • Phase I trial of a single dose of recombinant human interleukin-12 in human immunodeficiency virus infected patients with 100-500 CD4 cells/microL
    • Jacobson MA, Hardy D, Conninck E, Watson J, Debruin M. Phase I trial of a single dose of recombinant human interleukin-12 in human immunodeficiency virus infected patients with 100-500 CD4 cells/microL. J Infect Dis 2000 182 : 1070 6.
    • (2000) J Infect Dis , vol.182 , pp. 1070-6
    • Jacobson, M.A.1    Hardy, D.2    Conninck, E.3    Watson, J.4    Debruin, M.5
  • 44
    • 0037165878 scopus 로고    scopus 로고
    • AACTG 325 protocol team. a phase I, placebo-controlled trial of multi-dose recombinant human interleukin-12 in patients with HIV infection
    • Jacobson MA, Spritzler J, Landay A et al. AACTG 325 protocol team. A phase I, placebo-controlled trial of multi-dose recombinant human interleukin-12 in patients with HIV infection. AIDS 2002 16 : 1147 54.
    • (2002) AIDS , vol.16 , pp. 1147-54
    • Jacobson, M.A.1    Spritzler, J.2    Landay, A.3
  • 46
    • 0031824618 scopus 로고    scopus 로고
    • Increased immune activation precedes the inflection point of CD4 T cells and the increased serum virus load in human immunodeficiency virus infection
    • Salazar-Gonzalez JF, Martinez-Maza O, Nishanian P et al. Increased immune activation precedes the inflection point of CD4 T cells and the increased serum virus load in human immunodeficiency virus infection. J Infect Dis 1998 178 : 423 43.
    • (1998) J Infect Dis , vol.178 , pp. 423-43
    • Salazar-Gonzalez, J.F.1    Martinez-Maza, O.2    Nishanian, P.3


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