Oligopeptides and copeptides of homochiral sequence, via β-sheets, from mixtures of racemic α-amino acids, in a one-pot reaction in water; relevance to biochirogenesis

Journal of the American Chemical Society

Volumn 130, Issue 27, 2008, Pages 8651-8659

  Illos, Roni A ^a   Bisogno, Fabricio R ^a   Clodic, Gilles ^b   Bolbach, Gerard ^b   Weissbuch, Isabelle ^a   Lahav, Meir ^a  

^a WEIZMANN INSTITUTE OF SCIENCE   (Israel)

^b SORBONNE UNIVERSITÉ   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ACIDS; AMINATION; AMINES; AMINO ACIDS; ARSENIC COMPOUNDS; CHEMICAL REACTIONS; DEUTERIUM; MONOMERS; ORGANIC ACIDS; ORGANIC COMPOUNDS; POLYMERIZATION; POLYMERS; PROTEINS; SOLUTIONS;

AQUEOUS SOLUTIONS; ASYMMETRIC INDUCTION; BIOCHIROGENESIS; CARBONYL DIIMIDAZOLE (GDI); CHAIN ELONGATION; DL-PHENYLALANINE; ENANTIO; ENANTIOSPECIFIC; EVOLUTION (CO); HEXAPEPTIDES; HOMOCHIRAL; INITIATION (ELECTRIC DISCHARGES); ISOTACTIC; L-ISOLEUCINE (L-ILE); LEUCINE (LEU); MALDI TOF MS; N TERMINALS; OLIGO-PEPTIDES; ONE POT REACTIONS; PRECIPITATION (METALLOGRAPHY); PRIMARY AMINES;

PEPTIDES;

ALPHA AMINO ACID; AMINE; CARBONYLDIIMIDAZOLE; DEUTERIUM; HEXAPEPTIDE; HISTIDINE; IMIDAZOLE DERIVATIVE; ISOLEUCINE; LEUCINE; OLIGOPEPTIDE; PENTAPEPTIDE; PEPTIDE LIBRARY; PHENYLALANINE; TYROSINE; VALINE; WATER;

AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; AQUEOUS SOLUTION; ARTICLE; BETA SHEET; CHIRALITY; ENANTIOSELECTIVITY; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; POLYMERIZATION; STEREOCHEMISTRY;

AMINES; AMINO ACID SEQUENCE; AMINO ACIDS; OLIGOPEPTIDES; PROTEIN STRUCTURE, SECONDARY; SEQUENCE ANALYSIS, PROTEIN; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; STEREOISOMERISM; WATER;

EID: 46949086071     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja709969v     Document Type: Article

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