Of rodents and humans: A light microscopic and ultrastructural study on cardiomyocytes in pulmonary veins

International Journal of Medical Sciences

Volumn 5, Issue 3, 2008, Pages 152-158

  Mueller Hoecker, Josef ^a   Beitinger, Frigga ^a   Fernandez, Borja ^b   Bahlmann, Olaf ^a   Assmann, Gerald ^a   Troidl, Christian ^c   Dimomeletis, Ilias ^d   Kääb, Stefan ^d   Deindl, Elisabeth ^d  

^a UNIVERSITY OF MUNICH   (Germany)

^b UNIVERSITY OF MÁLAGA   (Spain)

^c KERCKHOFF HEART CENTER   (Germany)

^d LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

Author keywords

Atrial fibrillation; Cardiomyocytes; Electron microscopy; Pulmonary veins

Indexed keywords

COLLAGEN FIBER;

ADULT; AGED; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BAGG ALBINO MOUSE; BASEMENT MEMBRANE; C57BL 6 MOUSE; CELLULAR DISTRIBUTION; ELECTRON MICROSCOPY; FEMALE; HEART ATRIUM ARRHYTHMIA; HEART ATRIUM FIBRILLATION; HEART MUSCLE CELL; HUMAN; HUMAN CELL; HUMAN TISSUE; IMAGE ANALYSIS; LUNG HILUS; LUNG VEIN; MALE; MICROSCOPY; MOUSE; NONHUMAN; PATHOGENESIS; PULMONARY VEIN; RAT; SMOOTH MUSCLE FIBER; TRANSGENIC MOUSE; ULTRASTRUCTURE; VASCULAR ENDOTHELIUM; VEIN DIAMETER; WISTAR RAT;

EID: 46849105707     PISSN: None     EISSN: 14491907     Source Type: Journal    
DOI: 10.7150/ijms.5.152     Document Type: Article

References (28)

1. Ho SY, Cabrera JA, Tran VH, Farre J, Anderson RH, Sanchez-Quintana D. Architecture of the pulmonary veins: Relevance to radiofrequency ablation. Heart 2001, 86:265-270.
2. Moubarak JB, Rozwadowski JV, Strzalka CT, Buck WR, Tan WS, Kish GF, Kisiel T, Fronc HC, Maloney JD. Pulmonary veins-left atrial junction: anatomic and histological study. Pacing Clin Electrophysiol 2000, 23:1836-1838.
3. Nathan H, Eliakim M. The junction between the left atrium and the pulmonary veins: an anatomic study of human hearts. Circulation 1966, 34:412-422.
4. Stieda L. Ueber quergestreifte Muskelfasern in der Wand von Lungenenvenen. Arch f Mikr Anat 1877, 14:243.
5. Tagawa M, Higuchi K, Chinushi M, Washizuka T, Ushiki T, Ishihara N, Aizawa Y. Myocardium extending from the left atrium onto the pulmonary veins: a comparison between subjects with and without atrial fibrillation. Pacing Clin Electrophysiol 2001, 24:1459-1463.
6. Brunton TL, Fayer L. Note on independent pulsation of the pulmonary veins and vena cava. Proc R Soc B 1876, 25:174-176.
7. Masani F. Node-like cells in the myocardial layer of the pulmonary vein of rats: an ultrastructural study. J Anat 1986, 145:133-142.
8. Paes de Almeida O, Bohm CM, de Paula Carvalho M, Paes de Carvalho A. The cardiac muscle in the pulmonary vein of the rat: A morphological and electrophysiological study. J Morphol 1975, 145:409-434.
9. Perez-Lugones A, McMahon JT, Ratliff NB, Saliba WI, Schweikert RA, Marrouche NF, Saad EB, Navia JL, McCarthy PM, Tchou P, et al. Evidence of specialized conduction cells in human pulmonary veins of patients with atrial fibrillation. J Cardiovasc Electrophysiol 2003, 14:803-809.
10. Cheung DW. Pulmonary vein as an ectopic focus in digitalis-induced arrhythmia. Nature 1981, 294:582-584. .
11. Cheung DW. Electrical activity of the pulmonary vein and its interaction with the right atrium in the guinea-pig. J Physiol 1981, 314:445-456.
12. Hoffmann E, Janko S, Reithmann C, Steinbeck G. Mechanisms of initiation in atrial fibrillation. Z Kardiol 2002, 91:24-32.
13. Millino C, Sarinella F, Tiveron C, Villa A, Sartore S, Ausoni S. Cardiac and smooth muscle cell contribution to the formation of the murine pulmonary veins. Dev Dyn 2000, 218:414-425.
14. Mommersteeg MT, Brown NA, Prall OW, de Gier-de Vries C, Harvey RP, Moorman AF, Christoffels VM. Pitx2c and Nkx2-5 Are Required for the Formation and Identity of the Pulmonary Myocardium. Circ Res 2007, 101:902-909.
15. Hogan B, Beddington R, Costantini F, Lacy E. Microinjecting DNA into pronuclei; in Manipulating the mouse embryo - a laboratory manual. New York: Cold Spring Harbor Laboratory Press; 1994.
16. Heppleston AG. The musculature of the aging mouse lung. A light and electron-microscope study. J Gerontology 1961, 16:106-109.
17. Karrer HE. The striated musculature of blood vessels. I. General cell morphology. J Biophys Biochem Cytol. 1959, 6:383-392.
18. Ludatscher RM. Fine structure of the muscular wall of rat pulmonary veins. J Anat 1968, 103:345-357.
19. Kholova I, Kautzner J. Anatomic characteristics of extensions of atrial myocardium into the pulmonary veins in subjects with and without atrial fibrillation. Pacing Clin Electrophysiol 2003, 26:1348-1355.
20. Rutger J, Hassink RJ, Aretz HT, Ruskin J, Keane D. Morphology of atrial myocardium in human pulmonary veins. A postmortem analysis in patients with and without atrial fibrillation. J Am Coll Cardiol 2003, 42:1108-1114
21. Saito T, Waki K, Becker AE. Left atrial myocardial extensions onto pulmonary veins in humans: Anatomic observations relevant for atrial arrhythmias. J Cardiovasc Electrophysiol 2000, 11:888-894.
22. Roux N, Havet E, Mertl P. The myocardial sleeves of the pulmonary veins: potential implications for atrial fibrillation. Surg Radiol Anat 2004, 26:285-289.
23. Milanesi R, Baruscotti M, Gnecchi-Ruscone T, DiFrancesco D. Familial sinus bradycardia associated with a mutation in the cardiac pacemaker channel. N Engl J Med 2006, 354:151-157.
24. Stieber J, Herrmann S, Feil S, Loster J, Feil R, Biel M, et al. The hyperpolarization-activated channel HCN4 is required for the generation of pacemaker action potentials in the embryonic heart. Proc Natl Acad Sci U S A 2003, 100:15235-15240.
25. Webb S, Brown NA, Wessel A, Anderson RH. Development of the murine pulmonary vein and its relationship to the embryonic venous sinus. Anat Rec 1998, 250:325-334.
26. Jones WK, Sanchez A, Robbins J. Murine pulmonary myocardium: developmental analysis of cardiac gene expression. Dev Dyn 1994, 200:117-128.
27. Lyons GE, Schiaffino S, Sassoon D, Barton P, Buckingham ME. Developmental regulation of myosin expression in mouse cardiac muscle. J Cell Biol 1990, 111:2427-2437.
28. van den Hoff MJ, Kruithof BP, Moorman AF. Making more heart muscle. Bioessays 2004, 26:248-261.