One-stop measurement of iron deposition in the anterior pituitary, liver, and heart in thalassemia patients

Journal of Magnetic Resonance Imaging

Volumn 28, Issue 1, 2008, Pages 29-33

  Lam, Wynnie W M ^a   Au, W Y ^b   Chu, Winnie C W ^a   Tam, S ^c   Ha, S Y ^c   Pennell, D J ^d  

^a CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

^b UNIVERSITY OF HONG KONG   (Hong Kong)

^c QUEEN MARY HOSPITAL   (Hong Kong)

^d ROYAL BROMPTON HOSPITAL   (United Kingdom)

Author keywords

Iron load; Magnetic resonance imaging; Thalassemia major

Indexed keywords

FERRITIN; GROWTH HORMONE; SOMATOMEDIN BINDING PROTEIN 3; SOMATOMEDIN C;

ADENOHYPOPHYSIS; ADULT; ARTICLE; CLINICAL ARTICLE; FEMALE; GROWTH HORMONE BLOOD LEVEL; HEART; HUMAN; HYPOGONADISM; IRON STORAGE; LIVER; MALE; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; THALASSEMIA MAJOR;

ADOLESCENT; ADULT; CHILD; FEASIBILITY STUDIES; FEMALE; HUMANS; IRON; LIVER; MAGNETIC RESONANCE IMAGING; MALE; MYOCARDIUM; PITUITARY GLAND, ANTERIOR; THALASSEMIA;

EID: 46849083909     PISSN: 10531807     EISSN: 15222586     Source Type: Journal    
DOI: 10.1002/jmri.21433     Document Type: Article

References (20)

1. Tanner MA, Galanello R, Dessi C, et al. Myocardial iron loading in patients with thalassemia major on deferoxamine chelation. J Cardiovasc Magn Reson 2006;8:543-547.
2. Pennell DJ, Berdoukas V, Karagiorga M, et al. Randomized controlled trial of deferiprone or deferoxamine in beta-thalassemia major patients with asymptomatic myocardial siderosis. Blood 2006;107:3738-3744.
3. Tanner MA, Galanello R, Dessi C, et al. A randomized, placebo controlled double blind trial of the effect of combined therapy with deferoxamine and deferiprone on myocardial iron in thalassemia major using cardiovascular magnetic resonance. Circulation 2007; 115:1876-1884.
4. Westwood M, Anderson LJ, Firmin DN, et al. A single breath-hold multiecho T2* cardiovascular magnetic resonance technique for diagnosis of myocardial iron overload. J Magn Reson Imaging 2003; 18:33-39.
5. Maceira AM, Prasad SK, Khan M, Pennell DJ. Normalized left ventricular systolic and diastolic function by steady state free precession cardiovascular magnetic resonance. J Cardiovasc Magn Reson 2006;8:417-426.
6. Anderson LJ, Holden S, Davis B, et al. Cardiovascular 72-star (T2*) magnetic resonance for the early diagnosis of myocardial iron overload. Eur Heart J 2001;22:2171-2179.
7. Barosi G, Arbustini E, Gavazzi A, Grasso M, Pucci A. Myocardial iron grading by endomyocardial biopsy. A clinico pathologic study on iron overloaded patients. Eur J Haematol 1989;42:382-388.
8. Baraldi-Junkins C, Levin HR, Kasper EK, Rayburn BK, Herskowitz A, Baughman KL. Complications of endomyocardial biopsy in heart transplant patients. J Heart Lung Transplant 1993;12:63-67.
9. Angelucci E, Baronciani D, Lucarelli G, et al. Needle liver biopsy in thalassaemia: analyses of diagnostic accuracy and safety in 1184 consecutive biopsies. Br J Haematol 1995;89:757-761.
10. Bonkovsky HL, Slaker DP, Bills EB, Wolf DC. Usefulness and limitations of laboratory and hepatic imaging studies in iron-storage disease. Gastroenterology 1990;99:1079-1091.
11. Hernandez RJ, Sarnaik SA, Lande I, et al. MR evaluation of liver iron overload. J Comput Assist Tomogr 1988;12:91-94.
12. Jensen PD, Jensen FT, Christensen T, Ellegaard J. Non-invasive assessment of tissue iron overload in the liver by magnetic resonance imaging. Br J Haematol 1994;87:171-184.
13. Gandon Y, Guyader D, Heautot JF, et al. Hemochromatosis: diagnosis and quantification of liver iron with gradient echo MR imaging. Radiology 1994;193:533-538.
14. Kaltwasser JP, Gottschalk R, Schalk KP, Hartl W. Non invasive quantitation of liver iron overload by magnetic resonance imaging. Br J Hameatol 1990;74:360-363.
15. Chatterjee R, Katz M. Reversible hypogonadotrophic hypogonadism in sexually infantile male thalassaemic patients with transfusional iron overload. Clin Endocrinol 2000;53:33-42.
16. Chatterjee R, Katz M, Oatridge A, Bydder GM, Porter JB. Selective loss of anterior pituitary volume with severe pituitary-gonadal insufficiency in poorly compliant male thalassemic patients with pubertal arrest. Ann N Y Acad Sci 1998;850:479-482.
17. Atkin SL, Burnett HE, Green VL, White MC, Lombard M. Expression of the transferrin receptor in human anterior pituitary adenomas is confined to gonadotrophinomas. Clin Endocrinol 1996;44:467-471.
18. Sparacia G, Midiri M, D'Angelo P, Lagalla R. Magnetic resonance imaging of the pituitary gland in patients with secondary hypogonadism due to transfusional hemochromatosis. Magma 1999;8:87-90.
19. Tauber MT, Tauber JP, Vigoni F, Harris AG, Rochiccioli P. Effect of the long acting somatostatin analogue SMS 201-995 on growth rate and reduction of predicted adult height in ten tall adolescents. Acta Paediatr Scand 1990;79:176-181.
20. Attie KM, Carlsson LM, Rundle AC, Sherman BM. Evidence for partial growth hormone insensitivity among patients with idiopathic short stature. The National Cooperative Growth Study. J Pediatr 1995;127:244-250.