Association of interleukin-10 gene haplotypes with Pseudomonas aeruginosa airway colonization in cystic fibrosis

Journal of Cystic Fibrosis

Volumn 7, Issue 4, 2008, Pages 329-332

  Tesse, Riccardina ^a   Cardinale, Fabio ^a   Santostasi, Teresa ^a   Polizzi, Angela ^a   Mappa, Luigi ^a   Manca, Antonio ^a   De Robertis, Francesco ^a   Silecchia, Ombretta ^a   Armenio, Lucio ^a  

^a UNIVERSITY OF BARI   (Italy)

Author keywords

Cystic fibrosis; Gene polymorphism; Interleukin 10; Pseudomonas aeruginosa

Indexed keywords

ADENINE; CYSTEINE; CYTOKINE; CYTOSINE; GENOMIC DNA; GLYCINE; GUANINE; INTERLEUKIN 10; TRANSMEMBRANE CONDUCTANCE REGULATOR; TYROSINE;

ADOLESCENT; AMINO ACID SUBSTITUTION; ARTICLE; BACTERIAL COLONIZATION; CHILD; CYSTIC FIBROSIS; CYTOKINE PRODUCTION; DISEASE SEVERITY; FEMALE; FORCED EXPIRATORY VOLUME; GENE MUTATION; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GENETIC VARIABILITY; GENOTYPE; HAPLOTYPE; HUMAN; INFECTION RISK; ITALY; LUNG FUNCTION TEST; MAJOR CLINICAL STUDY; MALE; MEDICAL RECORD REVIEW; POLYMERASE CHAIN REACTION; PROMOTER REGION; PSEUDOMONAS AERUGINOSA; RESPIRATORY TRACT INFECTION; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; SINGLE NUCLEOTIDE POLYMORPHISM; SPUTUM CULTURE;

ADOLESCENT; ADULT; CHILD; CHILD, PRESCHOOL; COHORT STUDIES; CYSTIC FIBROSIS; FEMALE; GENETIC PREDISPOSITION TO DISEASE; HAPLOTYPES; HUMANS; INTERLEUKIN-10; MALE; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE; PROMOTER REGIONS, GENETIC; PSEUDOMONAS AERUGINOSA; PSEUDOMONAS INFECTIONS; YOUNG ADULT;

EID: 46749155967     PISSN: 15691993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jcf.2007.11.004     Document Type: Article

References (23)

1. Burns J.L., Gibson R.L., McNamara S., et al. Longitudinal assessment of Pseudomonas aeruginosa in young children with cystic fibrosis. J Infect Dis 183 (2001) 444-452
2. Cutting G.R. Modifier genetics: cystic fibrosis. Ann Rev Genom Hum Genet 6 (2005) 237-260
3. Fiorentino D.F., Zlotnik A., Mosmann T.R., Howard M., O'Garra, and A. IL-10 inhibits cytokine production by activated macrophages. J Immunol 147 (1991) 3815-3822
4. Konstan M.W., and Berger M. Current understanding of the inflammatory process in cystic fibrosis: onset and etiology. Pediatr Pulmonol 24 (1997) 137-142
5. Bonfield T.L., Panuska J.R., Konstan M.W., et al. Inflammatory cytokines in cystic fibrosis lungs. Am J Respir Crit Care Med 152 (1995)
6. Bonfield T.L., Konstan M.W., and Berger M. Altered respiratory epithelial cell cytokine production in cystic fibrosis. J Allergy Clin Immunol 104 1 (1999) 72-78
7. Chmiel J.F., Konstan M.W., Knesebeck J.E., et al. IL-10 attenuates excessive inflammation in chronic Pseudomonas infection in mice. Am J Respir Crit Care Med 160 (1999) 2040-2047
8. Turner D.M., Williams D.M., Sankaran D., Lazarus M., Sinnott P.J., and Hutchinson I.V. An investigation of polymorphism in the interleukin-10 gene promoter. Eur J Immunogenet 24 (1997) 1-8
9. Crawley E., Kai R., Sillibourne J., Patel P., Hutchinson I., and Woo P. Polymorphic haplotypes of the interleukin-10 5′ flanking region determine variable interleukin-10 transcription and are associated with particular phenotypes of juvenile rheumatoid arthritis. Arthritis Rheum 42 (1999) 1101-1108
10. Edwards-Smith C.J., Jonsson J.R., Purdie D.M., Bansal A., Shorthouse C., and Powell E.E. Interleukin-10 promoter polymorphism predicts initial response of chronic hepatitis C to Interferon alfa. Hepatology 30 (1999) 526-530
11. Gibson L.E., and Cooke R.E. A test for concentration of electrolytes in sweat in cystic fibrosis of the pancreas utilizing pilocarpine by iontophoresis. Pediatrics 23 (1959) 545-549
12. Kulczycki L.L., Kostuch M., and Bellanti J.A. A clinical prospective of cystic fibrosis and new genetic findings: relationship of CFTR mutations to genotype-phenotype manifestations. Am J Med Genet 116 (2003) 262-267
13. Trevisiol C., Boniotto M., Giglio L., Poli F., Morgutti M., and Crovella S. MBL2 polymorphisms screening in a regional Italian CF center. J Cyst Fibros 4 (2005) 189-191
14. Stephens M., Smith N.J., and Donnelly P. A new statistical method for haplotype reconstruction from population data. Am J Hum Genet 68 (2001) 978-989
15. Horvath S., Xu X., Lake S.L., et al. Family-based tests for associating haplotypes with general phenotype data: application to asthma genetics. Genet Epidemiol 26 (2004) 61-69
16. Parad R.B., Gerard C.J., Zurakowski D., Nichols D.P., and Pier G.B. Pulmonary outcome in cystic fibrosis is influenced primarily by mucoid Pseudomonas aeruginosa infection and immune status and only modestly by genotype. Infect Immun 67 (1999) 4744-4750
17. Jacques I., Derelle J., Weber M., and Vidailhet M. Pulmonary evolution of cystic fibrosis patients colonized by Pseudomonas aeruginosa and/or Burkholderia cepacia. Eur J Pediatr 157 (1998) 427-431
18. Casaulta C., Schoni M.H., Weichel M., et al. IL-10 controls Aspergillus fumigatus- and Pseudomonas aeruginosa-specific T-cell response in cystic fibrosis. Pediatr Res 53 (2003) 313-319
19. Brouard J., Knauer N., Boelle P.Y., et al. Influence of Interleukin-10 on Aspergillus fumigatus infection in patients with cystic fibrosis. J Infect Dis 191 (2005) 1988-1991
20. Gallagher P.M., Lowe G., Fitzgerald T., et al. Association of IL-10 polymorphism with severity of illness in community acquired pneumonia. Thorax 58 (2003) 154-156
21. Schaaf B.M., Boehmke F., Esnaashari H., et al. Pneumococcal septic shock is associated with the interleukin-10-1082 gene promoter polymorphism. Am J Respir Crit Care Med 168 (2003) 476-480
22. He J.Q., Shumansky K., Zhang X., et al. Polymorphisms of interleukin-10 and its receptor and lung function in COPD. Eur Respir J 29 (2007) 1120-1126
23. Lyon H., Lange C., Lake S., et al. IL10 gene polymorphisms are associated with asthma phenotypes in children. Genet Epidemiol 26 (2004) 155-165