The chondrogenic repair response of undifferentiated mesenchymal cells in rat full-thickness articular cartilage defects

Osteoarthritis and Cartilage

Volumn 16, Issue 8, 2008, Pages 961-964

  Anraku, Y ^a   Mizuta, H ^a   Sei, A ^a   Kudo, S ^a   Nakamura, E ^a   Senba, K ^a   Takagi, K ^a   Hiraki, Y ^b,c  

^a KUMAMOTO UNIVERSITY   (Japan)

^b KYOTO UNIVERSITY   (Japan)

^c JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

Author keywords

Chondrogenesis; Osteochondral defects; Rat articular cartilage; Tissue repair

Indexed keywords

CELL MARKER;

ACCURACY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ARTICULAR CARTILAGE; CARTILAGE CELL; CELL DIFFERENTIATION; CHONDROPATHY; CONTROLLED STUDY; DEVICE; HISTOLOGY; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; MALE; MESENCHYMAL STEM CELL; NONHUMAN; PATELLOFEMORAL JOINT; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; RATING SCALE; REGENERATION; RELIABILITY; TISSUE REPAIR;

ANIMALS; CARTILAGE, ARTICULAR; CELL DIFFERENTIATION; CHONDROCYTES; CHONDROGENESIS; MALE; MESENCHYMAL STEM CELLS; MODELS, ANIMAL; RATS; WOUND HEALING;

EID: 46749154288     PISSN: 10634584     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.joca.2007.12.009     Document Type: Article

References (7)

1. Buckwalter J., Rosenberg L., Coutts R., Hunziker E., Reddi A.H., and Mow V. Articular cartilage: injury and repair. In: Woo S.L.-Y., and Buckwalter J.A. (Eds). Injury and Repair of the Musculoskeletal Soft Tissues (1988), American Academy of Orthopaedic Surgeons, Park Ridge 465-482
2. Shapiro F., Koide S., and Glimcher M.J. Cell origin and differentiation in the repair of full-thickness defects of articular cartilage. J Bone Joint Surg Am 75 (1993) 532-553
3. Solchaga L.A., Goldberg V.M., and Caplan A.I. Cartilage regeneration using principles of tissue engineering. Clin Orthop Relat Res (2001) S161-S170
4. Otsuka Y., Mizuta H., Takagi K., Iyama K., Yoshitake Y., Nishikawa K., et al. Requirement of fibroblast growth factor signaling for regeneration of epiphyseal morphology in rabbit full-thickness defects of articular cartilage. Dev Growth Differ 39 (1997) 143-156
5. Kudo S., Mizuta H., Otsuka Y., Takagi K., and Hiraki Y. Inhibition of chondrogenesis by parathyroid hormone in vivo during repair of full-thickness defects of articular cartilage. J Bone Miner Res 15 (2000) 253-260
6. Mizuta H., Kudo S., Nakamura E., Otsuka Y., Takagi K., and Hiraki Y. Active proliferation of mesenchymal cells prior to the chondrogenic repair response in rabbit full-thickness defects of articular cartilage. Osteoarthritis Cartilage 12 (2004) 586-596
7. Mizuta H., Kudo S., Nakamura E., Takagi K., and Hiraki Y. Expression of the pth/pthrp receptor in chondrogenic cells during the repair of full-thickness defects of articular cartilage. Osteoarthritis Cartilage 14 (2006) 944-952