A generalizable strategy for imaging pre-mRNA levels in living subjects using spliceosome-mediated RNA trans-splicing

Journal of Nuclear Medicine

Volumn 49, Issue 7, 2008, Pages 1146-1154

  Walls, Zachary F ^a   Puttaraju, M ^b   Temple, Gary F ^c   Gambhir, Sanjiv Sam ^d  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b VIRxSYS Corporation   (United States)

^c NATIONAL HUMAN GENOME RESEARCH INSTITUTE   (United States)

^d STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Animal imaging; Molecular biology; Molecular imaging; RNA; Trans splicing

Indexed keywords

COMPLEMENTARY DNA; MESSENGER RNA; RENILLA LUCIFERIN 2 MONOOXYGENASE;

ARTICLE; CONTROLLED STUDY; GENE EXPRESSION; GENETIC TRANSFECTION; HYDRODYNAMICS; IMAGING; IN VIVO STUDY; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA SEQUENCE; RNA SPLICING; SPLICEOSOME; WESTERN BLOTTING;

ANIMALS; BINDING SITES; CELLS, CULTURED; GENES, REPORTER; HUMANS; LUCIFERASES; MICE; MICE, NUDE; PLASMIDS; RENILLA; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA PRECURSORS; SPLICEOSOMES; TRANS-SPLICING; TRANSFECTION;

EID: 46749148868     PISSN: 01615505     EISSN: None     Source Type: Journal    
DOI: 10.2967/jnumed.107.047662     Document Type: Article

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