Mean platelet volume not so far from being a routine diagnostic and prognostic measurement

Thrombosis and Haemostasis

Volumn 100, Issue 1, 2008, Pages 3-4

  Yetkin, Ertan ^a  

^a International Medical Center   (Turkey)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 6; THROMBOPOIETIN;

ATHEROSCLEROSIS; CARDIOVASCULAR DISEASE; CARDIOVASCULAR RISK; CELL DIFFERENTIATION; CEREBROVASCULAR DISEASE; CORONARY ARTERY DISEASE; DIAGNOSTIC PROCEDURE; EDITORIAL; HIGH RISK PATIENT; HUMAN; MEGAKARYOCYTE; PRIORITY JOURNAL; PROGNOSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; THROMBOCYTE COUNT; THROMBOCYTE STRUCTURE; THROMBOCYTE VOLUME; THROMBOCYTOPOIESIS;

ATHEROSCLEROSIS; BLOOD PLATELETS; CELL SIZE; DIAGNOSTIC TESTS, ROUTINE; HUMANS; MYOCARDIAL ISCHEMIA; OBESITY; PROGNOSIS;

EID: 46749139028     PISSN: 03406245     EISSN: None     Source Type: Journal    
DOI: 10.1160/TH08-05-0336     Document Type: Editorial

References (17)

1. Massberg S, Schulz C, Gawaz M. Role of platelets in the pathophysiology of acute coronary syndrome. Semin Vasc Med 2003; 3: 147-162.
2. Martin JF, Bath PMW, Burr ML. Influence of platelet size on outcome after myocardial infarction. Lancet 1991; 338: 1409-1411.
3. Bentfield-Barker ME, Bainton DF. Identification of primary lysosomes in human megakaryocytes and platelets. Blood 1982; 59: 472-481.
4. Hoffman R. Regulation of megakaryocytopoiesis. Blood 1989; 74: 1196-1212.
5. Kaushansky K, Lok S, Holly RD, et al. Promotion of megakaryocyte progenitor expansion and differentiation by the c-Mpl ligand thrombopoietin. Nature 1994; 369: 568-571.
6. Harker LA, Marzec UM, Hunt P, et al. Dose-response effects of pegylated human megakaryocyte growth and development factor on platelet production and function in nonhuman primates. Blood 1996; 88: 511-521.
7. Kojima, H, Shinagawa, A, Shimizu, S, et al. Role of phosphatidylinositol- 3 kinase and its association with Gab1 in thrombopoietin-mediated up-regulation of platelet function. Exp Hematol 2001; 29: 616-622.
8. Kuter DJ, Rosenberg RD. The reciprocal relationship of thrombopoietin (c-Mpl ligand) to changes in the platelet mass during busulfan-induced thrombocytopenia in the rabbit. Blood 1995; 85: 2720-2730.
9. Sungaran R, Markovic B, Chong BH. Localization and regulation of thrombopoietin mRNa expression in human kidney, liver, bone marrow, and spleen using in situ hybridization. Blood 1997; 89: 101-107.
10. Wolber EM, Fandrey J, Frackowski U, et al. Hepatic thrombopoietin mRNA is increased in acute inflammation. Thromb Haemost 2001; 86: 1421-1424.
11. Brown AS, Hong Y, de Belder A, et al. Megakaryocyte ploidy and platelet changes in human diabetes and atherosclerosis. Arterioscler Thromb Vasc Biol 1997; 17: 802-807.
12. SenaranH, Ileri M, Altinbas A, et al. Thrombopoietin and mean platelet volume in coronary artery disease. Clin Cardiol 2001; 24: 405-408.
13. Muscari A, Pascalis SD, Cenni1 A, et al. Determinants of mean platelet volume (MPV) in an elderly population: Relevance of body fat, blood glucose and ischaemic electrocardiographic changes. Thromb Haemost 2008; 99: 1079-1084.
14. Papanas N, Symeonidis G, Maltezos E, et al. Mean platelet volume in patients with type 2 diabetes mellitus. Platelets 2004; 15: 475-478.
15. Coban E, Ozdogan M, Yazicioglu G, et al. The mean platelet volume in patients with obesity. Int J Clin Pract 2005; 59: 981-982.
16. Sewell R, Ibbotson RM, Phillips R, et al. High mean platelet volume after myocardial infarction: is it due to consumption of small platelets? Br Med J 1984; 289: 1576-1578.
17. Cesari F, Marcucci R, Caporale R, et al. Relationship between high platelet turnover and platelet function in high-risk patients with coronary artery disease on dual antiplatelet therapy. Thromb Haemost 2008; 99: 930-935.