Humoral immunity to commensal oral bacteria in human infants: Evidence that Streptococcus mitis biovar 1 colonization induces strain-specific salivary immunoglobulin A antibodies

ISME Journal

Volumn 2, Issue 7, 2008, Pages 728-738

  Wirth, Katherine A ^a   Bowden, George H ^b   Kirchherr, Jennifer L ^a   Richmond, Dorothy A ^a   Sheridan, Michael J ^c   Cole, Michael F ^a  

^a GEORGETOWN UNIVERSITY MEDICAL CENTER   (United States)

^b UNIVERSITY OF MANITOBA   (Canada)

^c INOVA FAIRFAX HOSPITAL   (United States)

Author keywords

Infants; S. mitis biovar 1; Saliva; SIgA antibody

Indexed keywords

BACTERIUM ANTIBODY; SECRETORY IMMUNOGLOBULIN;

ANTIBODY PRODUCTION; ANTIBODY SPECIFICITY; ARTICLE; CLASSIFICATION; FEMALE; HUMAN; IMMUNOLOGY; INFANT; ISOLATION AND PURIFICATION; MALE; MICROBIOLOGY; PHYSIOLOGY; RIBOTYPING; SALIVA; SPECIES DIFFERENCE; STREPTOCOCCUS MITIS; SYMBIOSIS;

ANTIBODIES, BACTERIAL; ANTIBODY FORMATION; ANTIBODY SPECIFICITY; FEMALE; HUMANS; IMMUNOGLOBULIN A, SECRETORY; INFANT; MALE; RIBOTYPING; SALIVA; SPECIES SPECIFICITY; STREPTOCOCCUS MITIS; SYMBIOSIS;

BACTERIA (MICROORGANISMS); STREPTOCOCCUS MITIS;

EID: 46749138306     PISSN: 17517362     EISSN: 17517370     Source Type: Journal    
DOI: 10.1038/ismej.2008.26     Document Type: Article

References (17)

1. Bowden GH, Hamilton IR. 1998. Survival of oral bacteria. Crit Rev Oral Biol Med 9: 54-85.
2. Brandtzaeg P, Fjellanger I, Gjeruldsen ST. 1968. Adsorption of immunoglobulin A onto oral bacteria in vivo. J Bacteriol 96: 242-249.
3. Cole MF, Bryan S, Evans MK, Pearce CL, Sheridan MJ, Sura PA et al. 1998. Humoral immunity to commensal oral bacteria in human infants: salivary antibodies reactive with Actinomyces naeslundii genospecies 1 and 2 during colonization. Infect Immun 66: 4283-4289.
4. Cole MF, Bryan S, Evans MK, Pearce CL, Sheridan MJ, Sura PA et al. 1999. Humoral immunity to commensal oral bacteria in human infants: salivary secretory immunoglobulin A antibodies reactive with Streptococcus mitis biovar 1, Streptococus oralis, Streptococcus mutans, and Enterococcus faecalis during the first two years of life. Infect Immun 67: 1878-1886.
5. Cole MF, Evans MK, Kirchherr JL, Sheridan MJ, Bowden GH. 2004. Study of humoral immunity to commensal oral bacteria in human infants demonstrates the presence of secretory immunoglobulin A antibodies reactive with Actinomyces naeslundii genospecies 1 and 2 ribotypes. Clin Diagn Lab Immunol 11: 473-482.
6. Fitzsimmons SP, Evans M, Pearce C, Sheridan MJ, Wientzen R, Bowden G et al. 1996. Clonal diversity of Streptococcus mitis biovar 1 isolates from the oral cavity of human neonates. Clin Diagn Lab immunol 3: 517-522.
7. Fitzsimmons SP, Evans MK, Sheridan MJ, Wientzen R, Cole MF. 1994. Immunoglobulin A subclasses in infant's saliva and in saliva and milk from their mothers. J Pediatr 124: 566-573.
8. Gregory RL, Kindle JC, Hobbs LC, Filler SJ, Malmstrom HS. 1990. Function of anti-Streptococcus mutans antibodies: inhibition of virulence factors and enzyme neutralization. Oral Microbiol Immunol 5: 181-188.
9. Hohwy J, Kilian M. 1995. Clonal diversity of the Streptococcus mitis population in the human oral cavity and pharynx. Oral Microbiol Immunol 10: 19-25.
10. Hohwy J, Reinholdt J, Kilian M. 2001. Population dynamics of Streptococcus mitis in its natural habitat. Infect Immun 69: 6055-6063.
11. Kirchherr JL, Bowden GH, Richmond DA, Sheridan MJ, Wirth KA, Cole MF. 2005. Clonal diversity and turnover of Streptococcus mitis bv. 1 on shedding and nonshedding oral surfaces of human infants during the first year of life. Clin Diagn Lab Immunol 12: 1184-1190.
12. Mestecky J, McGhee JR. 1987. Immunoglobulin A (IgA): molecular and cellular interactions involved in IgA biosynthesis and immune response. Adv Immunol 40: 153-245.
13. Pearce C, Bowden GH, Evans M, Fitzsimmons SP, Johnson J, Sheridan MJ et al. (1995). Identification of pioneer viridans streptococci in the oral cavity of human neonates. J Med Microbiol 42: 67-72.
14. Quan CP, Berneman A, Pires R, Avrameas S, Bouvet J-P. 1997. Natural polyreactive secretory immunoglobulin A autoantibodies as a possible barrier to infection in humans. Infect Immun 65: 3997-4004.
15. Smith DJ, King WF, Taubman MA. 1990. Salivary IgA antibody to oral streptococcal antigens in predentate infants. Oral Microbiol Immunol 5: 57-62.
16. Smith DJ, Taubman MA, Ebersole JL. 1985. Salivary IgA antibody to glucosyl-transferase in man. Clin Exp Immunol 61: 416-424.
17. Widerstrom L, Bratthall D, Hamberg K. 1992. Immunoglobulin A antibody activity to mutans streptococci in parotid, submandibular and whole saliva. Oral Microbiol Immunol 7: 326-331.