Semisynthesis of H-Ras with a glutamic acid methylester at position 61

Biopolymers - Peptide Science Section

Volumn 90, Issue 3, 2008, Pages 399-405

  Milić, Jelena ^a   Seidel, Ralf ^a   Becker, Christian F W ^a   Goody, Roger S ^a   Engelhard, Martin ^a  

^a MAX PLANCK INSTITUTE OF MOLECULAR PHYSIOLOGY   (Germany)

Author keywords

Expressed protein ligation; GTPase mechanism; Unnatural amino acids

Indexed keywords

AMINES; AMINO ACIDS; ESCHERICHIA COLI; ESTERS; ORGANIC ACIDS; ORGANIC COMPOUNDS; PROTEINS;

CARBOXAMIDE; CONSTITUTIVELY ACTIVE; E. COLI; EXPRESSED PROTEIN LIGATION; GLUTAMIC ACID; GTP HYDROLYSIS; GTPASE ACTIVITY; GTPASE MECHANISM; GUANOSINE TRIPHOSPHATE; HYDROLYSIS REACTIONS; METHYL ESTERS; NATIVE CHEMICAL LIGATION; ONCOGENIC RAS; OPTIMAL REACTION CONDITIONS; REFOLDING; SEMI-SYNTHESIS; STILL MISSING; STRUCTURAL CHANGES; UNNATURAL AMINO ACIDS;

HYDROLYSIS;

GLUTAMIC ACID; GLUTAMINE; GUANOSINE TRIPHOSPHATASE; GUANOSINE TRIPHOSPHATE; PEPTIDE DERIVATIVE; RAS PROTEIN; ESTER; PEPTIDE;

AMINO ACID SYNTHESIS; AMINO TERMINAL SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CATALYSIS; ENZYME ACTIVITY; ESCHERICHIA COLI; HYDROGEN BOND; HYDROLYSIS; NONHUMAN; PEPTIDE SYNTHESIS; PROTEIN EXPRESSION; PROTEIN FOLDING; CHEMICAL STRUCTURE; CHEMISTRY; GENETICS; ISOLATION AND PURIFICATION; METABOLISM; MUTATION; SYNTHESIS;

CATALYSIS; ESCHERICHIA COLI; ESTERS; GLUTAMIC ACID; GTP PHOSPHOHYDROLASES; GUANOSINE TRIPHOSPHATE; HYDROGEN BONDING; HYDROLYSIS; MODELS, MOLECULAR; MUTATION; PEPTIDES; PROTEIN FOLDING; RAS PROTEINS;

EID: 46749136122     PISSN: 00063525     EISSN: 10970282     Source Type: Journal    
DOI: 10.1002/bip.20797     Document Type: Article

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