Modulation of AMP deaminase in rat hearts subjected to ischemia and reperfusion by purine riboside

Nucleosides, Nucleotides and Nucleic Acids

Volumn 27, Issue 6-7, 2008, Pages 876-880

  Borkowski, T ^a   Lipinski, M ^a   Kaminski, R ^a   Krzyminska Stasiuk, E ^a   Langowska, M ^a   Raczak, G ^a   Slominska, E M ^a   Smolenski, R T ^a,b,c  

^a MEDICAL UNIVERSITY OF GDANSK   (Poland)

^b IMPERIAL COLLEGE LONDON   (United Kingdom)

^c HAREFIELD HOSPITAL   (United Kingdom)

Author keywords

AMP deaminase; Cardiomyocytes; Heart; Ischemia reperfusion; Purine riboside; Rat

Indexed keywords

ADENINE NUCLEOTIDE; ADENOSINE MONOPHOSPHATE DEAMINASE; NEBULARINE;

ANIMAL CELL; ANIMAL EXPERIMENT; CONFERENCE PAPER; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; HEART MUSCLE CELL; HEART MUSCLE ISCHEMIA; HEART MUSCLE REPERFUSION; NONHUMAN; NUCLEOTIDE METABOLISM; RAT;

AMP DEAMINASE; ANIMALS; ENZYME ACTIVATION; HEART; ISCHEMIA; MYOCARDIUM; MYOCYTES, CARDIAC; NUCLEOTIDES; PURINE NUCLEOSIDES; REPERFUSION; RIBONUCLEOSIDES;

RATTUS;

EID: 46749087833     PISSN: 15257770     EISSN: 15322335     Source Type: Journal    
DOI: 10.1080/15257770802146551     Document Type: Conference Paper

References (6)

1. Loh, E.; Rebbeck, T.R.; Mahoney, P.D.; DeNofrio, D.; Swain, J.L.; Holmes, E.W. Common variant in AMPD1 gene predicts improved clinical outcome in patients with heart failure. Circulation. 1999, 99, 1422-1425.
2. de Groote P.; Lamblin, N.; Helbecque, N.; Mouquet, F.; Hermant, X.; Amouyel, P.; Dallongeville, J.; Bauters, C. The impact of the AMPD1 gene polymorphism on exercise capacity, other prognostic parameters, and survival in patients with stable congestive heart failure: a study in 686 consecutive patients. Am. Heart J. 2006, 152, 736-741.
3. Smolenski, R.T.; Amrani, M.; Jayakumar, J.; Jagodzinski, P.; Gray, C.C.; et al. Pyruvate/dichloroacetate supply during reperfusion accelerates recovery of cardiac energetics and improves mechanical function following cardioplegic arrest. Eur. J Cardiothorac. Surg., 2001, 19, 865-872.
4. Smolenski, R.T.; Lachno, D.R.; Ledingham, S.J.M.; Yacoub, M.H. Determination of sixteen nucleotides, nucleosides and bases using high-performance liquid chromatography and its application to the study of purine metabolism in hearts for transplantation. J . Chromatogr. 1990, 527, 414-420.
5. Smolenski, R.T. The elevation of adenylate pool in rat cardiomyocytes by S-adenosyl-L-methionine. Acta Biochim. Pol. 2000, 47, 1171-1178.
6. Kozlowska, M.; Smolenski, R.T.; Makarewicz, W.; Hoffmann, C.; Jastorff, B.; Swierczynski, J. ATP depletion, purine riboside triphosphate accumulation and thymocyte death induced by purine riboside. Toxicol. Lett. 1999, 104, 171-181.