Association of a bovine proin gene haplotype with atypical BSE

PLoS ONE

Volumn 3, Issue 3, 2008, Pages

  Clawson, Michael L ^a   Richt, Juergen A ^b   Baron, Thierry ^c   Biacabe, Anne Gaëlle ^c   Czub, Stefanie ^d   Heaton, Michael P ^a   Smith, Timothy P L ^a   Laegreid, William W ^a,e  

^a U S MEAT ANIMAL RESEARCH CENTER   (United States)

^b AGRICULTURAL RESEARCH SERVICE   (United States)

^c Healthy Pigs Production and Experimentation Section   (France)

^d CANADIAN FOOD INSPECTION AGENCY   (Canada)

^e UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PRION PROTEIN;

ARTICLE; BOVINE SPONGIFORM ENCEPHALOPATHY; CANADA; CATTLE; CONFIDENCE INTERVAL; CONTROLLED STUDY; EXON; FISHER EXACT TEST; FRANCE; GENETIC ASSOCIATION; GENETIC CODE; GENETIC POLYMORPHISM; GENETIC SUSCEPTIBILITY; HAPLOTYPE; INFECTION SENSITIVITY; INTRON; NONHUMAN; PROMOTER REGION; STATISTICAL SIGNIFICANCE; TWO TAILED TEST; UNITED STATES; UNTRANSLATED REGION; VIRAL GENETICS; ANIMAL; GENETICS; GENOTYPE; PRION;

BOS; BOVINAE;

ANIMALS; CATTLE; ENCEPHALOPATHY, BOVINE SPONGIFORM; GENOTYPE; HAPLOTYPES; POLYMORPHISM, GENETIC; PRIONS;

EID: 46649110354     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0001830     Document Type: Article

References (21)

1. Prusiner SB (1998) Prions. Proc Natt Acad Sci U S A 95: 13363-13383.
2. Brown P, McShane LM, Zanusso G, Detwiler L (2006) On the question of sporadic or atypical bovine spongiform encephalopathy and Creutzfeldt-Jakob disease. Emerg Infect Dis 12: 1816-1821.
3. Bruce ME, Will RG, Ironside JW, McConnell I, Drummond D, et al. (1997) Transmissions to mice indicate that 'new variant' CJD is caused by the BSE agent. Nature 389: 498-501.
4. Hill AF, Desbruslais M, Joiner S, Sidle KC, Gowland I, et al. (1997) The same prion strain causes vCJD and BSE. Nature 389: 448-450.
5. Sander P, Hamann H, Pfeiffer I, Wemheuer W, Brenig B, et al. (2004) Analysis of sequence variability of the bovine prion protein gene (PRNP) in German cattle breeds, Neurogenetics 5: 19-25.
6. Juling K, Schwarzenbacher H, Williams JL, Fries R (2006) A major genetic component of BSE susceptibility. BMC Biol 4: 33.
7. Haase B, Doherr MG, Seuberlich T, Drögemüller C, Dolf G, et al. (2007) PRNP promoter polymorphisms are associated with BSE susceptibility in Swiss and German cattle. BMC Genet 8: 15.
8. Brunelle BW, Hamir AN, Baron T, Biacabe AG, Richt JA, et al. (2007) Polymorphisms of the prion gene promoter region that influence classical bovine spongiform encephalopathy susceptibility are not applicable to other transmissible spongiform encephalopathies in cattle. J Anim Sci 85: 3142-3147.
9. Kovács GG, Puopolo M, Ladogana A, Pocchiari M, Budka H, et al. (2005) Genetic prion disease: the EUROCJD experience. Hum Genet 118: 166-174.
10. Heaton MP, Leymaster KA, Freking BA, Hawk DA, Smith TPL, et al. (2003) Prion gene sequence variation within diverse groups of U.S. sheep, beef cattle, and deer. Mamm Genome 14: 765-777.
11. Clawson ML, Heaton MP, Keele JW, Smith TPL, Harbay GP, et al. (2006) Prion gene haplotypes of U.S. cattle. BMC Genet 7: 51.
12. Baron T, Biacabe A-G, Arsac J-N, Benestad S, Groschup MH (2006) Atypical transmissible spongiform encephalopathies (TSEs) in ruminants. Vaccine 25: 5625-5630.
13. Biacabe A-G, Laplanche J-L, Ryder S, Baron T (2004) Distinct molecular phenotypes in bovine prion diseases. EMBO Rep 5: 110-115.
14. Richt JA, Kunkle RA, Alt D, Nicholson EM, Hamir AN, et al. (2007) Identification and characterization of two bovine spongiform encephalopathy cases diagnosed in the United States. J Vet Diagn Invest 19: 142-154.
15. Heaton MP, Chitko-McKown CG, Grosse WM, Keele JW, Keen JE, et al. (2001) Interleukin-8 haplotype structure from nucleotide sequence variation in commercial populations of U.S. beef cattle. Mamm Genome 12: 219-226.
16. Heaton MP, Keen JE, Clawson MI, Harhay GP, Bauer N, et al. (2005) Use of bovine single nucleotide polymorphism markers to verify sample tracking in beef processing. J Am Vet Med Assoc 226: 1311-1314.
17. Smith TP, Godtel RA, Lee RT (2000) PCR-based setup for high-throughput cDNA library sequencing on the ABI 3700 automated DNA sequencer. Biotechniques 29: 698-700.
18. Stephens M, Sloan JS, Robertson PD, Scheet P, Nickerson DA (2006) Automating sequence-based detection and genotyping of SNPs from diploid samples. Nat Genet 38: 375-381.
19. Stephens, M, Smith NJ, Donnelly P (2001) A new statistical method for haplotype reconstruction from population data. Am J of Hum Genet 68: 978-989.
20. Stephens M, Scheet P (2005) Accounting for decay of linkage disequilibrium in haplotype inference and missing-data imputation. Am J of Hum Genet 76: 449-462.
21. Abramson JH (2004) WINPEPI (PEPI-for-Windows): computer programs for epidemiologists. Epidemiol Perspect Innov 1: 6.