Management of patients with high sperm DNA damage

Indian Journal of Medical Research

Volumn 127, Issue 2, 2008, Pages 101-103

  Moskovtsev, S I ^a  

^a MOUNT SINAI HOSPITAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA TOCOPHEROL; ANTIOXIDANT; ASCORBIC ACID; LIPOCORTIN 5; PHOSPHATIDYLSERINE; POLYUNSATURATED FATTY ACID; REACTIVE OXYGEN METABOLITE;

ALGORITHM; APOPTOSIS; CELL SELECTION; DNA DAMAGE; DNA FRAGMENTATION; DNA PACKAGING; DNA SYNTHESIS; EDITORIAL; ELECTROPHORESIS; EMBRYO DEVELOPMENT; ENZYME SYNTHESIS; FERTILIZATION IN VITRO; HUMAN; INFERTILITY THERAPY; INTRACYTOPLASMIC SPERM INJECTION; MALE FERTILITY; MALE INFERTILITY; NICK END LABELING; NIDATION; OXIDATIVE STRESS; PREGNANCY RATE; SEMEN ANALYSIS; SEMINAL PLASMA; SPERM; SPERMATOZOON MATURATION; SPONTANEOUS ABORTION; TESTIS DEVELOPMENT;

CELL MEMBRANE; DNA DAMAGE; FEMALE; HUMANS; MALE; OXIDATIVE STRESS; PREGNANCY; PREGNANCY RATE; SPERM INJECTIONS, INTRACYTOPLASMIC; SPERMATOZOA;

EID: 46649098028     PISSN: 09715916     EISSN: 09715916     Source Type: Journal    
DOI: None     Document Type: Editorial

References (18)

1. Evenson DP, Jost LK, Marshall D, Zinaman MJ, Clegg E, Purvis K, et al. Utility of the sperm chromatin structure assay as a diagnostic and prognostic tool in the human fertility clinic. Hum Reprod 1999; 14: 1039-49.
2. Zini A, Bielecki R, Phang D, Zenzes MT. Correlations between two markers of sperm DNA integrity, DNA denaturation and DNA fragmentation, in fertile and infertile men. Fertil Steril 2001; 75: 674-7.
3. Benchaib M, Lornage J, Mazoyer C, Lejeune H, Salle B, Francois Guerin J. Sperm deoxyribonucleic acid fragmentation as a prognostic indicator of assisted reproductive technology outcome. Fertil Steril 2007; 87: 93-100.
4. Spano M, Bonde JP, Hjollund HI, Kolstad HA, Cordelli E, Leter G. Sperm chromatin damage impairs human fertility. The Danish First Pregnancy Planner Study Team. Fertil Steril 2000; 73: 43-50.
5. Tesarik J, Greco E, Mendoza C. Late, but not early, paternal effect on human embryo development is related to sperm DNA fragmentation. Hum Reprod 2004; 19: 611-5.
6. Carrell DT, Liu L, Peterson CM, Jones KP, Hatasaka HH, Erickson L, et al. Sperm DNA fragmentation is increased in couples with unexplained recurrent pregnancy loss. Arch Androl 2003; 49: 49-55.
7. Agarwal A, Said TM. Role of sperm chromatin abnormalities and DNA damage in male infertility. Hum Reprod Update 2003; 9: 331-45.
8. Aitken RJ. Clarkson JS, Fishel S. Generation of reactive oxygen species, lipid peroxidation, and human sperm function. Biol Reprod 1989; 41: 183-97.
9. Greco E, Iacobelli M, Rienzi L, Ubaldi F, Ferrero S, Tesarik J. Reduction of the incidence of sperm DNA fragmentation by oral antioxidant treatment. J Androl 2005; 26: 349-53.
10. Silver EW, Eskenazi B, Evenson DP, Block G, Young S, Wyrobek AJ. Effect of antioxidant intake on sperm chromatin stability in healthy non-smoking men. J Androl 2005; 26: 550-6.
11. Verpoest W, Tournaye H. ICS1: hype or hazard? Hum Fertil 2006; 9: 81-92.
12. Gandini L, Lombardo F, Paoli D, Caruso F, Eleuteri P, Leter G, et al. Full-term pregnancies achieved with ICSI despite high levels of sperm chromatin damage. Hum Reprod 2004; 19: 1409-17.
13. Tomlinson MJ, Moffatt O, Manicardi GC, Bizzaro D, Afhan M, Sakkas D. Interrelationships between seminal parameters and sperm nuclear DNA damage before and after density gradient centrifugation: implications for assisted conception. Hum Reprod 2001; 16: 2160-5.
14. Said TM, Grunewald S, Paasch U, Glander HJ, Baumann T, Kriegel C, et al. Advantage of combining magnetic cell separation with sperm preparation techniques. Reprod Bio Med Online 2005; 10: 740-6.
15. Ainsworth C, Nixon B, Jansen RP, Aitken RJ. First recorded pregnancy and normal birth after ICSI using electrophoretically isolated spermatozoa. Hum Reprod 2007; 22: 197-200.
16. Hazout A, Dumont-Hassan M, Junca AM, Cohen Bacrie P, Tesarik J. High-magnification ICSI overcomes paternal effect resistant to conventional ICSI. Reprod Biomed Online 2006; 12: 19-25.
17. Greco E, Scarselli F, Iacobelli M, Rienzi L, Ubaldi F, Ferrero S, et al. Efficient treatment of infertility due to sperm DNA damage by ICSI with testicular spermatozoa. Hum Reprod 2005; 20: 226-30.
18. Nicopoullos JD, Ramsay JW, Almeida PA, Gilling-Smith C. Assisted reproduction in the azoospermic couple. BJOG 2004; 111: 1190-203.