Gradual stretching of the proximal nerve stump induces the growth of regenerating sprouts in rats

Journal of Orthopaedic Research

Volumn 26, Issue 7, 2008, Pages 1012-1017

  Saijilafu, ^a   Nishiura, Yasumasa ^a   Hara, Yuki ^a   Yoshii, Yuichi ^a   Ochiai, Naoyuki ^a  

^a UNIVERSITY OF TSUKUBA   (Japan)

Author keywords

Proximal nerve stump; Rats; Regenerating sprouts; Stretching

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; DEVICE; MALE; MYELIN SHEATH; NERVE FIBER; NERVE FIBER GROWTH; NERVE FIBER REGENERATION; NONHUMAN; PRIORITY JOURNAL; PROXIMAL NERVE STUMP STRETCHING; RAT; SCIATIC NERVE; STRETCHING; SUTURE; ANIMAL; INJURY; NERVE REGENERATION; NERVOUS SYSTEM INJURY; PHYSIOLOGY; ULTRASTRUCTURE; WISTAR RAT;

ANIMALS; AXONS; MALE; NERVE REGENERATION; RATS; RATS, WISTAR; SCIATIC NERVE; TRAUMA, NERVOUS SYSTEM;

EID: 46449126622     PISSN: 07360266     EISSN: None     Source Type: Journal    
DOI: 10.1002/jor.20587     Document Type: Article

References (27)

1. Chada S, Lamoureux P, Buxbaum RE, et al. 1997. Cytomechanics of neurite outgrowth from chick brain neurons. J Cell Sci 110:1179-1186.
2. Dennerll TJ, Lamoureus P, Buxbaum RE, et al. 1989. The cytomechanics of axonal elongation and retraction. J Cell Biol 109:3073-3083.
3. Heidemann SR, Lamoureux P, Buxbaum RE. 1995. Cytomechanics of axonal development. Cell Biochem Biophys 27:135-155.
4. Lamoureux P, Buxbaum RE, Heidemann SR. 1989. Direct evidence that growth cone pull. Nature 340:159-162.
5. Zheng J, Lamoureux P, Santiago V, et al. 1991. Tensile regulation of axonal elongation and initiation. J Neurosci 11: 1117-1125.
6. Saijilafu, Nishiura Y, Yamada Y, et al. 2006. Repair of peripheral nerve defect with direct gradual lengthening of the proximal nerve stump in rats. J Orthop Res 24:2246-2253.
7. Abe I, Ochiai N, Ichimura H, et al. 2004. Internodes can nearly double in length with gradual elongation of the adult rat sciatic nerve. J Orthop Res 22:571-577.
8. Krober MW, Diao E, Hida S, et al. 2001. Peripheral nerve lengthening by controlled isolated distraction: a new animal model. J Orthop Res 19:70-77.
9. Orbay J, Lin H, Kummer FJ. 1993. Repair of peripheral nerve defects by controlled distraction: a preliminary study. Bull Hosp Joint Dis 52:7-10.
10. Dyck PK. 1975. Pathologic alterations of the peripheral nervous system of man. In: Dyck PJ, Thomas PK, Lambert EH, editors. Peripheral neuropathy, 2nd ed. Philadelphia, PA: Saunders; p 296-336.
11. Tohyama K, Osawa T, Tajima K. 1997. Nerve allograft. In: Shimizi G, Ide C, Kawamura K, editors. Nerve regeneration and functional reconstruction, 1st ed. Tokyo, PA: Nishimura-syoten; p 227-249 (in Japanese).
12. Beuche W, Friede RL. 1985. A new approach toward analyzing peripheral nerve fiber populations. II. Foreshortening of regenerated internodes corresponds to reduced sheath thickness. J Neuropathol Exp Neurol 44:73-84.
13. Hiscoe HB. 1947. Distribution of nodes and incisures in normal and regenerated nerve fibres. Anat Rec 99:447-475.
14. Hildebrand C, Kocsis JD, Berglund S, et al. 1985. Myelin sheath remodelling in regenerated rat sciatic nerve. Brain Res 385:163-179.
15. Bischoff A, Thomas PK. 1975. Microscopic anatomy of myelinated nerve fibers. In: Dyck PJ, Thomas PK, Lambert EH, editors. Peripheral neuropathy, 2nd ed. Philadelphia, PA: Saunders; p 104-130.
16. Ahmed AM, Weller RO. 1979. The blood-nerve barrier and reconstitution of the perineurium following nerve grafting. Neuropathol Appl Neurobiol 5:469-483.
17. Morris JH, Hudson AR, Weddell G. 1972. A study of degeneration and regeneration in the divided rat sciatic nerve based on electron microscopy. Z Zellforsch 124:1-203.
18. Mackinnon SE, Dellon AL, O'Brien JP. 1991. Changes in nerve fiber numbers distal to a nerve repair in the rat sciatic nerve model. Muscle Nerve 14:1116-1122.
19. Fujimoto E, Mizoguchi A, Hanada K, et al. 1997. Basic fibro-blast growth factor promotes extension of regenerating axons of peripheral nerve. In vivo experiments using a Schwann cell basal lamina tube model. J Neurocytol 26:511-528.
20. Heumann R, Korsching S, Bandtlow C, et al. 1987. Changes of nerve growth factor synthesis in nonneuronal cells in response to sciatic nerve transection. J Cell Biol 104:1623-1631.
21. Liu HM, Yang LH, Yang YJ. 1995. Schwann cell properties: 3. C-fos expression, bFGF production, phagocytosis and proliferation during Wallerian degeneration. J Neuropathol Exp Neurol 54:487-496.
22. Meyer M, Matsuoka I, Wetmore C, et al. 1992. Enhanced synthesis of brain-derived neurotrophic factor in the lesioned peripheral nerve: different mechanisms are responsible for the regulation of BDNF and NGF mRNA. J Cell Biol 119: 45-54.
23. Taniuchi M, Clark HB, Schweitzer JB, et al. 1988. Expression of nerve growth factor receptors by Schwann cells of axotomized peripheral nerves: ultrastructural location, suppression by axonal contact, and binding properties. J Neurosci 8:664-681.
24. Baier H, Bonhoeffer F. 1992. Axon guidance by gradients of a target-derived component. Science 255:472-475.
25. Gundersen RW, Barrett JN. 1979. Neuronal chemotaxis: chick dorsal root axons turn towards concentrations of nerve growth factor. Science 206:1079-1080.
26. Zheng M, Kuffler DP. 2000. Guidance of regenerating motor axons in vivo by gradients of diffusible peripheral nerve-derived factors. J Neurobiol 42:212-219.
27. Perez NL, Sosa MA, Kuffler DP. 1997. Growth cones turn up concentration gradients of diffusible peripheral target-derived factors. Exp Neurol 145:196-202.