Osmotic regulation of a novel flavin-containing monooxygenase in primary cultured cells from rainbow trout (Oncorhynchus mykiss)

Drug Metabolism and Disposition

Volumn 36, Issue 7, 2008, Pages 1212-1217

  Rodríguez Fuentes, Gabriela ^a   Aparicio Fabre, Rosaura ^a   Li, Qi ^a   Schlenk, Daniel ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CIS ACTING ELEMENT; COMPLEMENTARY DNA; DIMETHYLANILINE MONOOXYGENASE; GLUCOCORTICOID; HYDROCORTISONE; SODIUM CHLORIDE; SODIUM SULFATE;

ANIMAL CELL; ARTICLE; CELL VIABILITY; CONTROLLED STUDY; DNA RESPONSIVE ELEMENT; GILL; LIVER CELL; MOLECULAR CLONING; NONHUMAN; NUCLEOTIDE SEQUENCE; OSMOREGULATION; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PUFFER FISH; RAINBOW TROUT; SEQUENCE ANALYSIS; SEQUENCE HOMOLOGY; SOUTHERN BLOTTING; TISSUE SPECIFICITY; ZEBRA FISH;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; CELLS, CULTURED; CLONING, MOLECULAR; DNA PRIMERS; DNA, COMPLEMENTARY; EXONS; HUMANS; INTRONS; MOLECULAR SEQUENCE DATA; ONCORHYNCHUS MYKISS; OSMOSIS; OXYGENASES; PROMOTER REGIONS (GENETICS); RNA, MESSENGER; SEQUENCE HOMOLOGY, AMINO ACID;

DANIO RERIO; ONCORHYNCHUS MYKISS; SALMONIDAE; TAKIFUGU; TAKIFUGU RUBRIPES; VERTEBRATA;

EID: 46449104798     PISSN: 00909556     EISSN: 1521009X     Source Type: Journal    
DOI: 10.1124/dmd.107.019968     Document Type: Article

References (22)

1. Breathnach R and Chamhon P (1981) Organization and expression of eucaritic split genes ending for proteins. Ann Rev Biochem 50:349-383.
2. Cashman JR (1995) Structural and catalytic properties of the mammalian flavin-containing monooxygenase. Chem Res Toxicol 8:165-181.
3. Cashman JR (2004) The implication of polymorphisms in mammalian flavin-containing monooxygenases in drug discovery and development. Drug Discov Today 9:574-581.
4. El-Alfy A, Larsen B, and Schlenk D (2002) Effect of cortisol and urea on flavin monooxygenase activity and expression in rainbow trout, Oncorhynchus mykiss. Mar Env Res 54:275-278.
5. El-Alfy A and Schlenk D (2002) Effect of 17β-estradiol and testosterone on the expression of flavin containing monooxygenase and the toxicity of aldicarb to Japanese medaka, Oryzias latipes. Toxicol Sci 68:381-388.
6. Eswaramoorthy S, Bonanno JB, Burley SK, and Swaminathan S (2006) Mechanism of action of a flavin-containing monooxygenase. Proc Natl Acad Sci U S A 103:9832-9837.
7. Ferraris JD, Williams CK, Jung KY, Bedford JJ, Burg MB, and Garcia-Perez A (1996) ORE, a eukaryotic minimal essential osmotic response element: the aldose reductase gene in hyper-osmotic stress. J Biol Chem 271:18318-18321.
8. Hines RN, Hopp KA, Franco J, Saeian K, and Begun FP (2002) Alternative processing of the human hepatic FM06 gene renders transcripts incapable of encoding a functional flavin containing monooxygenase. Mol Pharmacol 62:320-325.
9. Hines RN, Luo Z, Hopp KA, Cahacungan ET, Koukouritaki SB, and Mccarver DG (2003) Genetic variability at the human FMO1 locus: significance of a basal promoter Yin Yang l element polymorphism (FMO1*6). J Pharmacol Exp Ther 306:1210-1218.
10. Klick DE and Hines RN (2007) Mechanisms regulating human FM03 transcription. Drug Metab Rev 39:419-442.
11. Krueger SK and Williams DE (2005) Mammalian flavin-containing monooxygenases: structure/function, genetic polymorphisms and role in drug metabolism. Pharmacol Ther 106:357-387.
12. Larsen BK and Schlenk D (2001) Effect of salinity on flavin-containing monooxygenase expression and activity in rainbow trout (Onchorhynchus mykiss). J Camp Physiol B 171: 421-429.
13. Lattard V, Zhang J, and Cashman JR (2004) Alternative processing of flavin-containing monooxygenase (FMO) pre-mRNA in human. Mol Pharmacol 65:1517-1525.
14. Lawton MP, Cashman JR, Cresteil T, Dolphin CT, Elfarra AA, Hines RN, Hogson E, Kimura T, Ozols J, and Phillips IR (1994) A nomenclature for the mammalian flavin-containing monooxygenase gene family based on amino acid sequence identities. Arch Biochem Biophys 308:254-257.
15. Lee M-Y, Smiley S, Kadkhodayan S, Hines RN, and Williams DE (1995) Developmental regulation of flavin-containing monooxygenase (FMO) isoforms 1 and 2 in pregnant rabbit. Chem Biol Interact 96:75-85.
16. Luo Z and Hines RN (2001) Regulation of flavin-containing monooxygenase 1 expression by Ying Yang 1 and hepatic nuclear factors 1 and 4. Mol Pharmacol 60:1421-1430.
17. Rettie AE and Fisher MB (1999) Handbook of drug metabolism (Woolf TF ed) pp 131-145, Marcel Dekker, New York.
18. Sandbacka M and Isomaa B (2000) Glutathione S-transferase and UDP-glucuronyltransferase activity in primary cultures of rainbow trout gill epithelial cells. Comp Biochem Physiol C Toxicol Pharmacol 127:307-315.
19. Schlenk D, Peters LD, and Livingstone DR (1996) Correlation of salinity with flavin-containing monooxygenase activity but not cytochrome P450 activity in the euryhaline fish (Platichthys flesus). Biochem Pharmacol 52:815-818.
20. Wang J, Grisle S, and Schlenk D (2001) Effects of salinity on aldicarb toxicity in juvenile rainbow trout (Onchorhynchus mykiss) and stripped bass (Morone saxatilis x chrysops). Toxicol Sci 64:200-207.
21. Wyatt MK, Philpot RM, Carver G, Lawton MP, and Nikbakht KN (1996) Structural characteristics of flavin-containing monooxygenase genes one and two (FMO1 and FMO2). Drug Metab Dispos 24:1320-1327.
22. Ziegler DM (1988) Flavin-containing monooxygenases: catalytic mechanisms and substrate specificities. Drug Met Rev 19:1-32.