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Volumn 36, Issue 7, 2008, Pages 1414-1424

In silico methods for unraveling the mechanistic complexities of intestinal absorption: Metabolism-efflux transport interactions

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME P450; DRUG METABOLIZING ENZYME; GLYCOPROTEIN P;

EID: 46449103183     PISSN: 00909556     EISSN: 1521009X     Source Type: Journal    
DOI: 10.1124/dmd.107.020164     Document Type: Article
Times cited : (16)

References (9)
  • 3
    • 0036175307 scopus 로고    scopus 로고
    • Unmasking the dynamic interplay between intestinal P-glycoprotein and CYP3A4
    • Cummins CL, Jacobsen W, and Benet LZ (2002) Unmasking the dynamic interplay between intestinal P-glycoprotein and CYP3A4. J Pharmacol Exp Ther 300:1036-1045.
    • (2002) J Pharmacol Exp Ther , vol.300 , pp. 1036-1045
    • Cummins, C.L.1    Jacobsen, W.2    Benet, L.Z.3
  • 4
    • 0037382316 scopus 로고    scopus 로고
    • In vivo modulation of intestinal CYP3A metabolism by P-glycoprotein: Studies using the rat single-pass intestinal perfusion model
    • Cummins CL, Salphati L, Reid MJ, and Benet LZ (2003) In vivo modulation of intestinal CYP3A metabolism by P-glycoprotein: studies using the rat single-pass intestinal perfusion model. J Pharmacol Exp Ther 305:306-314.
    • (2003) J Pharmacol Exp Ther , vol.305 , pp. 306-314
    • Cummins, C.L.1    Salphati, L.2    Reid, M.J.3    Benet, L.Z.4
  • 5
    • 85047685271 scopus 로고    scopus 로고
    • Predictive models for oral drug absorption: From in silico methods to integrated dynamical models
    • Dokoumetzidis A, Kalantzi L, and Fotaki N (2007) Predictive models for oral drug absorption: from in silico methods to integrated dynamical models. Exp Opin Drug Metab Toxicol 3:491-505.
    • (2007) Exp Opin Drug Metab Toxicol , vol.3 , pp. 491-505
    • Dokoumetzidis, A.1    Kalantzi, L.2    Fotaki, N.3
  • 6
    • 33750181267 scopus 로고    scopus 로고
    • Regional levels of drug transporters along the human intestinal tract: Co-expression of ABC and SLC transporters and comparison with CACO-2 cells
    • Englund G, Rorsman F, Ronnblom A, Karlbom U, Lazorova L, Grasjo J, Kindmark A, and Artursson P (2006) Regional levels of drug transporters along the human intestinal tract: co-expression of ABC and SLC transporters and comparison with CACO-2 cells. Eur J Pharm Sci 29:269-277.
    • (2006) Eur J Pharm Sci , vol.29 , pp. 269-277
    • Englund, G.1    Rorsman, F.2    Ronnblom, A.3    Karlbom, U.4    Lazorova, L.5    Grasjo, J.6    Kindmark, A.7    Artursson, P.8
  • 8
    • 3042748444 scopus 로고    scopus 로고
    • Nanomedicine
    • Landes Bioscience, Georgetown, TX
    • Freitas Jr RA (1999) Nanomedicine, Volume I: Basic Capabilities, Landes Bioscience, Georgetown, TX.
    • (1999) Basic Capabilities , vol.1
    • Freitas Jr, R.A.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.