Investigations concerning the correlation of COX-1 inhibitory and hydroxyl radical scavenging activity

Archiv der Pharmazie

Volumn 341, Issue 5, 2008, Pages 281-287

  Scholz, Michael ^a   Ulbrich, Holger ^a   Mattern, Andreas ^a   Kramb, Jan Peter ^a   Kiefer, Werner ^a   Dannhardt, Gerd ^a  

^a JOHANNES GUTENBERG UNIVERSITY   (Germany)

Author keywords

Carboxylic acids; COX 1; Hydroxyl radical scavenging; SAR

Indexed keywords

3,4 DI(4 METHOXYPHENYL) 1H PYRROKL 2 CARBOXYLIC ACID; 4,5 DI(4 METHOXYPHENYL)ISOTHIAZOLE 3(2H)ON 1,1 DIOXIDE; ACETYLSALICYLIC ACID; ANTIOXIDANT; CARBOXYLIC ACID; CARBOXYLIC ACID DERIVATIVE; CYCLOOXYGENASE 1; CYCLOOXYGENASE 1 INHIBITOR; DICLOFENAC; ESTER; ETHYL 2 [4,5 DI(4 METHOXYPHENYL)ISOTHIAZOLE 3(2H)ON 1,1 DIOXIDE 2 YL]ACETATE; ETHYL 3,4 DI(4 METHOXYPHENYL) 1H PYRROL 2 CARBOXYLATE; HYDROXYL RADICAL; INDOMETACIN; SCAVENGER; UNCLASSIFIED DRUG; PROSTAGLANDIN SYNTHASE INHIBITOR;

ANIMAL CELL; ANTIOXIDANT ACTIVITY; ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; DRUG EFFICACY; DRUG MECHANISM; DRUG POTENCY; DRUG SYNTHESIS; ENZYME INHIBITION; NONHUMAN; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION; ANIMAL; CATTLE; DRUG EFFECT; METABOLISM;

ANIMALS; CATTLE; CYCLOOXYGENASE 1; CYCLOOXYGENASE INHIBITORS; FREE RADICAL SCAVENGERS; HYDROXYL RADICAL; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 46449099903     PISSN: 03656233     EISSN: 15214184     Source Type: Journal    
DOI: 10.1002/ardp.200700247     Document Type: Article

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