Functional and histological changes in rat lung after boron neutron capture therapy

Radiation Research

Volumn 170, Issue 1, 2008, Pages 60-69

  Kiger, Jingli Liu ^a   Kiger III, W S ^c   Riley, Kent J ^b   Binns, Peter J ^b   Patel, Hemant ^c,f   Hopewell, John W ^d   Harling, Otto K ^a   Busse, Paul M ^e   Coderre, Jeffrey A ^a  

^a Massachusetts Institute of Technology Cambridge   (United States)

^b MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

^d CHURCHILL HOSPITAL   (United Kingdom)

^e MASSACHUSETTS GENERAL HOSPITAL   (United States)

^f PFIZER INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 BORONOPHENYLALANINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BREATHING RATE; CONTROLLED STUDY; HISTOPATHOLOGY; LUNG INJURY; MALE; NEUTRON CAPTURE THERAPY; NONHUMAN; PRIORITY JOURNAL; RADIATION DOSE; RADIATION INJURY; RAT;

ANIMALS; BORON; BORON NEUTRON CAPTURE THERAPY; DOSE-RESPONSE RELATIONSHIP, RADIATION; ISOTOPES; LUNG; MALE; RATS; RATS, INBRED F344; RESPIRATION;

RATTUS;

EID: 46449097399     PISSN: 00337587     EISSN: None     Source Type: Journal    
DOI: 10.1667/RR1266.1     Document Type: Article

References (43)

1. J. A. Coderre, J. C. Turcotte, K. J. Riley, P. J. Binns, O. K. Harling and W. S. Kiger, III, Boron neutron capture therapy: Cellular targeting of high linear energy transfer radiation. Tech. Cancer Res. Treat. 2, 355-375 (2003).
2. R. F. Barth, J. A. Coderre, M. G. Vicente and T. E. Blue, Boron neutron capture therapy of cancer: Current status and future prospects. Clin. Cancer Res. 11, 3987-4002 (2005).
3. J. A. Coderre and G. M. Morris, The radiation biology of boron neutron capture therapy. Radiat. Res. 151, 1-18 (1999).
4. A. D. Chanana, J. Capala, M. Chadha, J. A. Coderre, A. Z. Diaz, E. H. Elowitz, J. Iwai, D. D. Joel, H. B. Liu and L. Wielopolski, Boron neutron capture therapy for glioblastoma multiforme: interim results from the phase I/II dose-escalation studies. Neurosurgery 44, 1182-1193 (1999).
5. M. R. Palmer, J. T. Goorley, W. S. Kiger, III, P. M. Busse, K. J. Riley, O. K. Harling and R. G. Zamenhof, Treatment planning and dosimetry for the Harvard-MIT Phase I clinical trial of cranial neutron capture therapy. Int. J. Radiat. Oncol. Biol. Phys. 53, 1361-1379 (2002).
6. P. M. Busse, O. K. Harling, M. R. Palmer, W. S. Kiger, III, J. Kaplan, I. Kaplan, C. F. Chuang, J. T. Goorley, K. J. Riley and R. G. Zamenhof, A critical examination of the results from the Harvard-MIT NCT program phase I clinical trial of neutron capture therapy for intracranial disease. J. Neurooncol. 62, 111-121 (2003).
7. A. Z. Diaz, Assessment of the results from the phase I/II boron neutron capture therapy trials at the Brookhaven National Laboratory from a clinician's point of view. J. Neurooncol. 62, 101-109 (2003).
8. W. S. Kiger, III, X. Q. Lu, O. K. Harling, K. J. Riley, P. J. Binns, J. Kaplan, H. Patel, R. G. Zamenhof, Y. Shibata and M. R. Palmer, Preliminary treatment planning and dosimetry for a clinical trial of neutron capture therapy using a fission converter epithermal neutron beam. Appl. Radiat. Isot. 61, 1075-1081 (2004).
9. 10B in blood after boronophenylalanine-fructose administration in humans. Radiat. Res. 155, 611-618 (2001).
10. K. Riley and O. Harling, An improved prompt gamma neutron activation analysis facility using a focused diffracted neutron beam. Nucl. Instrum. Methods B 143, 414-421 (1998).
11. O. K. Harling, K. J. Riley, P. J. Binns, H. Patel and J. A. Coderre, The MIT user center for neutron capture therapy research. Radiat. Res. 164, 221-229 (2005).
12. J. L. Kiger, W. S. Kiger, III, H. Patel, P. J. Binns, K. J. Riley, J. W. Hopewell, O. K. Harling and J. A. Coderre, Effects of boron neutron capture irradiation on the normal lung of rats. Appl. Radiat. Isot. 61, 969-973 (2004).
13. K. J. Riley, P. J. Binns and O. K. Harling, Performance characteristics of the MIT fission converter based epithermal neutron beam. Phys. Med. Biol. 48, 943-958 (2003).
14. J. A. Coderre, T. M. Button, P. L. Micca, C. D. Fisher, M. M. Nawrocky and H. B. Liu, Neutron capture therapy of the 9L rat gliosarcoma using the p-boronophenylalanine-fructose complex. Int. J. Radiat. Oncol. Biol. Phys. 30, 643-652 (1994).
15. G. M. Morris, P. L. Micca, M. M. Nawrocky, L. E. Weissfloch and J. A. Coderre, Long-term infusions of p-boronophenylalanine for boron neutron capture therapy: Evaluation using rat brain tumor and spinal cord models. Radiat. Res. 158, 743-752 (2002).
16. G. M. Morris, J. A. Coderre, P. L. Micca, C. D. Fisher, J. Capala and J. W. Hopewell, Central nervous system tolerance to boron neutron capture therapy with p-boronophenylalanine. Br. J. Cancer 76, 1623-1629 (1997).
17. J. L. Kiger, J. A. Coderre and W. S. Kiger, III, An automated method for breathing frequency determination for rat lung radiobiology in BNCT. In Advances in Neutron Capture Therapy 2006 (Y. Nakagawa, H. Kobayashi and H. Fukuda, Eds.), pp. 77-80. ISNCT, Takamatsu, 2006.
18. E. L. Travis, The sequence of histological changes in mouse lungs after single doses of X-rays. Int. J. Radiat. Oncol. Biol. Phys. 6, 345-347 (1980).
19. A. Ashcroft, J. M. Simpson and V. Timbrell, Simple method of estimating severity of pulmonary fibrosis on a numerical scale. J. Clin. Pathol. 41, 467-470 (1988).
20. K. F. Fu, Influence of dose rate on normal tissue tolerance. In Radiation Injury to the Nervous System (P. H. Gutin, S. A. Leibel and G. E. Sheline, Eds.), pp. 69-87. Raven Press, New York, 1991.
21. J. D. Down, D. F. Easton and G. G. Steel, Repair in the mouse lung during low dose-rate irradiation. Radiother. Oncol. 6, 29-42 (1986).
22. P. R. Gavin, S. L. Kraft, R. Huiskamp and J. A. Coderre, A review: CNS effects and normal tissue tolerance in dogs. J. Neurooncol. 33, 71-80 (1997).
23. L. Cohen and M. Awschalom, Fast neutron radiation therapy. Annu. Rev. Biophys. Bioeng. 11, 359-390 (1982).
24. N. J. Gross, Pulmonary effects of radiation-therapy. Ann. Intern. Med. 86, 81-92 (1977).
25. J. E. Coggle, B. E. Lambert and S. R. Moores, Radiation effects in the lung. Environ. Health Perspect. 70, 261-291 (1986).
26. A. Novakova-Jiresova, P. van Luijk, H. van Goor, H. H. Kampinga and R. P. Coppes, Pulmonary radiation injury: Identification of risk factors associated with regional hypersensitivity. Cancer Res. 65, 3568-3576 (2005).
27. E. L. Travis and J. D. Down, Repair in mouse lung after split doses of X rays. Radiat. Res. 87, 166-174 (1981).
28. H. R. Withers, L. J. Peters, H. D. Thames and G. H. Fletcher, Hyperfractionation. Int. J. Radiat. Oncol. Biol. Phys. 8, 1807-1809 (1982).
29. E. L. Travis, C. S. Parkins, J. D. Down, J. F. Fowler and H. D. Thames, Jr., Repair in mouse lung between multiple small doses of X rays. Radiat. Res. 94, 326-339 (1983).
30. W. S. Kiger, III, P. L. Micca, G. M. Morris and J. A. Coderre, Boron microquantification in oral mucosa and skin following administration of a neutron capture therapy agent. Radiat. Protect. Dosim. 99, 409-412 (2002).
31. S. Chandra, I. D. Lorey and D. R. Smith, Quantitative subcellular secondary ion mass spectrometry (SIMS) imaging of boron-10 and boron-11 isotopes in the same cell delivered by two combined BNCT drugs: In vitro studies on human glioblastoma T98G cells. Radiat. Res. 157, 700-710 (2002).
32. A. Tilikidis and A. Brahme, Microdosimetric description of beam quality and biological effectiveness in radiation therapy. Acta Oncol. 33, 457-469 (1994).
33. L. Lindborg and A. Brahme, Influence of microdosimetric quantities on observed dose-response relationships in radiation therapy. Radiat. Res. 124 (Suppl.), S23-S28 (1990).
34. C. J. H. Fryer, P. J. Fitzpatrick, W. D. Rider and P. Poon, Radiation pneumonitis: experience following a large single dose of radiation. Int. J. Radiat. Oncol. Biol. Phys. 4, 931-936 (1978).
35. T. J. Keane, J. Van Dyk and W. D. Rider, Idiopathic interstitial pneumonia following bone marrow transplantation: the relationship with total body irradiation. Int. J. Radiat. Oncol. Biol. Phys. 7, 1365-1370 (1981).
36. J. van Dyk, T. J. Keane, S. Kan, W. D. Rider and C. J. Fryer, Radiation pneumonitis following large single dose irradiation: A reevaluation based on absolute dose to lung. Int. J. Radiat. Oncol. Biol. Phys. 7, 461-467 (1981).
37. A. Wambersie, F. Richard and N. Breteau, Development of fast neutron therapy worldwide - Radiobiological, clinical and technical aspects. Acta. Oncol. 33, 261-274 (1994).
38. M. Suzuki, Y. Sakurai, S. Masunaga, Y. Kinashi, K. Nagata, A. Maruhashi and K. Ono, Feasibility of boron neutron capture therapy (BNCT) for malignant pleural mesothelioma from a viewpoint of dose distribution analysis. Int. J. Radiat. Oncol. Biol. Phys. 66, 1584-1589 (2006).
39. M. Suzuki, Y. Sakurai, S. Masunaga, Y. Kinashi, K. Nagata, A. Maruhashi and K. Ono, A preliminary experimental study of boron neutron capture therapy for malignant tumors spreading in thoracic cavity. Jpn. J. Clin. Oncol. 37, 245-249 (2007).
40. S. S. Vedam, V. R. Kini, P. J. Keall, V. Ramakrishnan, H. Mostafavi and R. Mohan, Quantifying the predictability of diaphragm motion during respiration with a noninvasive external marker. Med. Phys. 30, 505-513 (2003).
41. G. S. Mageras and E. Yorke, Deep inspiration breath hold and respiratory gating strategies for reducing organ motion in radiation treatment. Semin. Radiat. Oncol. 14, 65-75 (2004).
42. M. J. Murphy, Tracking moving organs in real time. Semin. Radiat. Oncol. 14, 91-100 (2004).
43. G. Sharp, A. Jeung, X. Tang, H. Mostafavi, G. Chen and S. Jiang, Respiratory gating with gantry mounted fluoroscopic imaging. Med. Phys. 33, 2047-2048 (2006).