Symptom patterns in functional dyspepsia and irritable bowel syndrome: Relationship to disturbances in gastric emptying and response to a nutrient challenge in consulters and non-consulters

Gut

Volumn 53, Issue 10, 2004, Pages 1445-1451

  Haag, S ^b   Talley, N J ^c   Holtmann, G ^a,b  

^a UNIVERSITY OF ADELAIDE   (Australia)

^b UNIVERSITY HOSPITAL ESSEN   (Germany)

^c MAYO CLINIC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARBON 13; OCTANOIC ACID;

ABDOMINAL DISCOMFORT; ABDOMINAL PAIN; ADULT; AGED; ARTICLE; BLOOD DONOR; BREATH ANALYSIS; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DYSPEPSIA; FEMALE; FUNCTION TEST; HUMAN; IRRITABLE COLON; MAJOR CLINICAL STUDY; MALE; MOTOR PERFORMANCE; NUTRIENT; PRIORITY JOURNAL; PROVOCATION TEST; QUESTIONNAIRE; RANDOMIZED CONTROLLED TRIAL; STOMACH EMPTYING; STOMACH FUNCTION; STOMACH MOTILITY; STOMACH ULCER; SYMPTOMATOLOGY;

ADOLESCENT; ADULT; AGE DISTRIBUTION; AGED; BREATH TESTS; DRINKING; DYSPEPSIA; FEMALE; GASTRIC EMPTYING; HELICOBACTER INFECTIONS; HELICOBACTER PYLORI; HUMANS; IRRITABLE BOWEL SYNDROME; MALE; MIDDLE AGED; SATIATION; SEX DISTRIBUTION;

EID: 4644359907     PISSN: 00175749     EISSN: None     Source Type: Journal    
DOI: 10.1136/gut.2003.030049     Document Type: Article

References (46)

1. Talley NJ, Stanghellini V, Heading RC, et al. Functional gastroduodenal disorders. Gut 1999;45(suppl 2):II37-42.
2. Holtmann G, Goebell H, Talley NJ. Dyspepsia in consulters and non-consulters: prevalence, health-care seeking behavior and risk factors. Eur J Gastroenterol Hepatol 1994;6:917-24.
3. Tack J, Piessevaux H, Coulie B, et al. Role of impaired gastric accommodation to a meal in functional dyspepsia. Gastroenterology 1998;115:1346-52.
4. Thumshirn M, Camilleri M, Saslow SB, et al. Gastric accommodation in non-ulcer dyspepsia and the roles of Helicobacter pylori infection and vagal function. Gut 1999;44:55-64.
5. Holtmann G, Goebell H, Jockenhoevel F, et al. Altered vagal and intestinal mechanosensory function in chronic unexplained dyspepsia. Gut 1998;42:501-6.
6. Holtmann G, Gschossmann J, Neufang-Huber J, et al. Differences in gastric mechanosensory function after repeated ramp distensions in non-consulters with dyspepsia and healthy controls. Gut 2000;47:332-6.
7. Malagelada JR. Gastrointestinal motor disturbances in functional dyspepsia. Scand J Gastroenterol Suppl 1991;182:29-32.
8. Mayer EA, Raybould HE. Role of visceral afferent mechanisms in functional bowel disorders. Gastroenterology 1990;99:1688-704.
9. Mayer EA, Gebhart GF. Basic and clinical aspects of visceral hyperalgesia. Gastroenterology 1994;107:271-93.
10. Stanghellini V, Tosetti C, Barbara G, et al. Risk indicators of delayed gastric emptying of solids in patients with functional dyspepsia. Gastroenterology 1996;110:1036-42.
11. Boeckxstaens GE, Hirsch DP, van den Elzen BD, et al. Impaired drinking capacity in patients with functional dyspepsia: relationship with proximal stomach function. Gastroenterology 2001;121:1054-63.
12. Talley NJ, Verlinden M, Jones M. Can symptoms discriminate among those with delayed or normal gastric emptying in dysmotility-like dyspepsia? Am J Gastroenterol 2001;96:1422-8.
13. Tack J, Caenepeel P, Piessevaux H, et al. Assessment of meal induced gastric accommodation by a satiety drinking test in health and in severe functional dyspepsia. Gut 2003;52:1271-7.
14. Blaser MJ, Duncan DJ. Human serum antibody response to Campylobacter jejuni infection as measured in an enzyme-linked immunosorbent assay. Infect Immun 1984;44:292-8.
15. Talley NJ, Phillips SF, Melton J iii, et al. A patient questionnaire to identify bowel disease. Ann Intern Med 1989;111:671-4.
16. Holtmann G, Goebell H, Holtmann M, et al. Dyspepsia in health blood donors. Pattern of symptoms and association with Helicobacter pylori. Dig Dis Sci 1994;39:1090-8.
17. Drossman DA. The functional gastrointestinal disorders and the Rome II process. Gut 1999;45(suppl 2):111-5.
18. Ghoos YF, Maes BD, Geypens BJ, et al. Measurement of gastric emptying rate of solids by means of a carbon-labeled octanoic acid breath test. Gastroenterology 1993;104:1640-7.
19. Holtmann G, Talley NJ, Neufang-Hüber J, et al. Comparison of gastric mechanosensory thresholds and maximal tolerance of a liquid meal. Gastroenterology 1996;110:A680.
20. SAS Institute Inc. SAS/STAT Software. Changes and enhancements through release 6.12. Cary, NC: SAS Institute, 1997.
21. Camilleri M, Brown ML, Malagelada JR. Relationship between impaired gastric emptying and abnormal gastrointestinal motility. Gastroenterology 1986;91:94-9.
22. Sarnelli G, Caenepeel P, Geypens B, et al. Symptoms associated with impaired gastric emptying of solids and liquids in functional dyspepsia. Am J Gastroenterol 2003;98:783-8.
23. Piessevaux H, Tack J, Walrand S, et al. Intragastric distribution of a standardized meal in health and functional dyspepsia: correlation with specific symptoms. Neurogastroenterol Motil 2003;15:447-55.
24. Koloski NA, Talley NJ, Huskic SS, et al. Predictors of conventional and alternative health care seeking for irritable bowel syndrome and functional dyspepsia. Aliment Pharmacol Ther 2003;17:841-51.
25. Kettell J, Jones R, Lydeard S. Reasons for consultation in irritable bowel syndrome: symptoms and patient characteristics. Br J Gen Pract 1992;42:459-61.
26. Cheng C. Seeking medical consultation: perceptual and behavioral characteristics distinguishing consulters and nonconsulters with functional dyspepsia. Psychosom Med 2000;62:844-52.
27. Westbrook JI, McIntosh J, Talley NJ. Factors associated with consulting medical or non-medical practitioners for dyspepsia: an Australian population-based study. Aliment Pharmacol Ther 2000;14:1581-8.
28. Lydeard S, Jones R. Factors affecting the decision to consult with dyspepsia: comparison of consulters and non-consulters. J R Coll Gen Pract 1989;39:495-8.
29. Corinaldesi R, Stanghellini V, Raiti C, et al. Effect of chronic administration of cisapride on gastric emptying of a solid meal and on dyspeptic symptoms in patients with idiopathic gastroparesis. Gut 1987;28:300-5.
30. Sturm A, Holtmann G, Goebell H, et al. Prokinetics in patients with gastroparesis: a systematic analysis. Digestion 1999;60:422-7.
31. Talley NJ, Verlinden M, Snape W, et al. Failure of a motilin receptor agonist (ABT-229) to relieve the symptoms of functional dyspepsia in patients with and without delayed gastric emptying: a randomized double-blind placebo-controlled trial. Aliment Pharmacol Ther 2000;14:1653-61.
32. Veldhuyzen van Zanten SJ, Jones MJ, Verlinden M, et al. Efficacy of cisopride and domperidone in functional (nonulcer) dyspepsia: a meta-analysis. Am J Gastroenterol 2001;96:689-96.
33. Agreus L, Talley NJ, Svardsudd K, et al. Identifying dyspepsia and irritable bowel syndrome: the value of pain or discomfort, and bowel habit descriptors. Scand J Gastroenterol 2000;35:142-51.
34. Talley NJ, Zinsmeister AR, Schleck CD, et al. Dyspepsia and dyspepsia subgroups: a population-based study. Gastroenterology 1992;102:1259-68.
35. Talley NJ, Holtmann G, Agreus L, et al. Gastrointestinal symptoms and subjects cluster into distinct upper and lower groupings in the community: a four nations study. Am J Gastroenterol 2000;95:1439-47.
36. Whitehead WE, Delvaux M. Standardization of barostat procedures for testing smooth muscle tone and sensory thresholds in the gastrointestinal tract. The Working Team of Glaxo-Wellcome Research, UK. Dig Dis Sci 1997;42:223-41.
37. Kuiken SD, Samsom M, Camilleri M, et al. Development of a test to measure gastric accommodation in humans. Am J Physiol 1999;277:G1217-21.
38. Ahluwalia NK, Thompson DG, Barlow J, et al. Relaxation responses of the human proximal stomach to distension during fasting and after food. Am J Physiol 1994;267:G166-72.
39. Hartley MN, Mackie CR. Gastric adaptive relaxation and symptoms after vagotomy. Br J Surg 1991;78:24-7.
40. Kerlin P. Postprandial antral hypomotility in patients with idiopathic nausea and vomiting. Gut 1989;30:54-9.
41. Agreus L, Svardsudd K, Nyren O, et al. Irritable bowel syndrome and dyspepsia in the general population: overlap and lack of stability over time. Gastroenterology 1995;109:671-80.
42. Grainger SL, Klass HJ, Rake MO, et al. Prevalence of dyspepsia: the epidemiology of overlapping symptoms. Postgrad Med J 1994;70:154-61.
43. Vaira D, Miglioli M, Mule P, et al. Prevalence of peptic ulcer in Helicobacter pylori positive blood donors. Gut 1994;35:309-12.
44. Chang CS, Chen GH, Kao CH, et al. Delayed gastric emptying does not predispose to Helicobacter pylori infection in non-ulcer dyspepsia patients. Nucl Med Commun 1995;16:1063-7.
45. Scott AM, Kellow JE, Shuter B, et al. Intragastric distribution and gastric emptying of solids and liquids in functional dyspepsia. Lack of influence of symptom subgroups and H. pylori-associated gastritis. Dig Dis Sci 1993;38:2247-54.
46. Wegener M, Borsch G, Schaffstein J, et al. Are dyspeptic symptoms in patients with Campylobacter pylori-associated type B gastritis linked to delayed gastric emptying? Am J Gastroenterol 1988;83:737-40.