Stability-indicating high-performance thin-layer chromatographic determination of zidovudine as the bulk drug and in pharmaceutical dosage forms

Journal of Planar Chromatography - Modern TLC

Volumn 17, Issue 4, 2004, Pages 264-274

  Kaul, Neeraj ^a   Agrawal, Himani ^a   Paradkar, Anant Raghunath ^a   Mahadik, Kakasaheb Ramoo ^a  

^a BHARATI VIDYAPEETH DEEMED UNIVERSITY   (India)

Author keywords

Degradation; Desitometry; HPTLC; Stability indicating analysis; Zidovudine

Indexed keywords

ABSORPTION; ACTIVATION ENERGY; ALUMINUM; CARBON TETRACHLORIDE; INORGANIC ACIDS; KETONES; METHANOL; POLYCYCLIC AROMATIC HYDROCARBONS; REACTION KINETICS; REGRESSION ANALYSIS; SILICA GEL; THIN LAYER CHROMATOGRAPHY;

ALKALINE HYDROLYSIS; COMPACT SPOTS; WET HEAT TREATMENT; ZIDOVUDINE;

DRUG PRODUCTS;

ACETONE; ALUMINUM; CARBON TETRACHLORIDE; METHANOL; SILICA GEL; TOLUENE; ZIDOVUDINE;

ACCURACY; ANALYTIC METHOD; ARTICLE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CORRELATION COEFFICIENT; DEGRADATION KINETICS; DENSITOMETRY; DRUG CAPSULE; DRUG DEGRADATION; DRUG DETERMINATION; DRUG DOSAGE FORM; DRUG FORMULATION; DRUG PURITY; DRUG STABILITY; DRUG STRUCTURE; HEAT TREATMENT; HIGH PERFORMANCE THIN LAYER CHROMATOGRAPHY; HUMAN IMMUNODEFICIENCY VIRUS; HYDROLYSIS; LINEAR REGRESSION ANALYSIS; OXIDATION; PHOTODEGRADATION; PROCESS OPTIMIZATION; QUANTITATIVE ANALYSIS; SENSITIVITY ANALYSIS; SEPARATION TECHNIQUE; STATISTICAL ANALYSIS;

EID: 4644355938     PISSN: 09334173     EISSN: None     Source Type: Journal    
DOI: 10.1556/JPC.17.2004.4.5     Document Type: Article

References (22)

1. J.E.F. Reynold (Ed.) Martindale, The Extra Pharmacopoeia, 30th edn, Pharmaceutical Press, London, 1993.
2. P.A. Furman, J.A. Fyte, M.H. Clair, K. Weinhold, J.L. Rideout, G.A. Freeman, S.N. Lehrman, D.P. Bolognesi, S. Broder, H. Mitsuya, and D.W. Barry, Proc. Natl Acad. Sci. USA 83 (1986) 8333.
3. G.X. McLeod and S.M. Hammer, Ann. Intern. Med. 117 (1992) 487-501.
4. K. Peter, J.P. Lalezari, and J.G. Gambertoglio, J. Pharm. Biomed. Anal. 14 (1996) 491-499.
5. X. Tan and F.D. Boudinot, J. Chromatogr. B 740 (2000) 281-287.
6. T. Nadal, J. Ortuno, and J.A. Pascual, J. Chromatogr. A 721 (1996) 127-137.
7. K.B. Kenny, S.A. Wring, R.M. Corr, G.N. Wells, and J.A. Dunn, J. Pharm. Biomed. Anal. 22 (2000) 967-983.
8. A.S. Pereira, K.B. Kenny, M.S. Cohen, and J.E. Hall, J. Chromatogr. B 742 (2000) 173-183.
9. V.A. Simon, M.D. Thiam, and L.C. Lipford, J. Chromatogr. A 913 (2001) 447-453.
10. E. Marchei, L. Valvo, and R. Pacifici, J. Pharm. Biomed. Anal. 29 (2002) 1081-1088.
11. B. Fan and J.T. Steward, J. Pharm. Biomed. Anal. 28 (2002) 903-908.
12. G. Aymard, M. Legrand, N. Trichereau, and B. Diquet, J. Chromatogr. B 744 (2000) 227-240.
13. B. Uslu and S.A. Ozkan, Anal. Chim. Acta 466 (2002) 175-185.
14. ICH, Q1A Stability Testing of New Drug Substances and Products, International Conference on Harmonization, Geneva, October 1993.
15. K. Ferenczi-Fodor, Z. Végh, A. Nagy-Turák, B. Renger, and M. Zeller, J. AOAC Int. 84 (2001) 1265-1276.
16. K. Ferenczi-Fodor and Z. Végh, in: Sz. Nyiredy (Ed.) Planar chromatography - A retrospective view for the third millennium, Springer, Budapest, 2001, pp. 336-352.
17. Thin Layer Chromatography, monograph 2.2.27, European Pharmacopoeia, Council of Europe, 4.5, 2002, p. 3638.
18. ICH, Q2A Validation of Analytical Procedure: Methodology, International Conference on Harmonization, Geneva, October, 1994.
19. ICH, Q2B Validation of Analytical Procedure: Methodology, International Conference on Harmonization, Geneva, March, 1996.
20. ICH Guidance on Analytical Method Validation, International Convention on Quality for the Pharmaceutical Industry, Toronto, Canada, September, 2002.
21. P.D. Sethi, High Performance Thin Layer Chromatography, Quantitative Analysis of Pharmaceutical Formulations, CBS, 1996.
22. E.R. Garrett and R.F. Carper, J. Am. Pharm. Assoc. Sci. 44 (1955) 515-521.