Synthesis of 5-benzoyl-6-trifluoromethyl-1,2-dihydro-3H-pyrrolo[1,2-a] pyrrole-1-carboxylic acid

Heterocycles

Volumn 63, Issue 9, 2004, Pages 2071-2077

  Zúñiga, Adrián Covarrubias ^a  

^a UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO   (Mexico)

Author keywords

[No Author keywords available]

Indexed keywords

3 METHOXYCARBONYL 4 TRIFLUOROMETHYL 5 BENZYLOXYCARBONYLPYRROLE 2 ACETIC ACID METHYL ESTER; 5 BENZOYL 6 TRIFLUOROMETHYL 1,2 DIHYDRO 3H PYRROLO[1,2 A]PYRROLE 1 CARBOXYLIC ACID; CARBOXYLIC ACID; ESTER; PYRROLE DERIVATIVE; UNCLASSIFIED DRUG;

ANALGESIC ACTIVITY; ANTIINFLAMMATORY ACTIVITY; ARTICLE; DECARBOXYLATION; DRUG STRUCTURE; DRUG SYNTHESIS; HYDROLYSIS; PROTON NUCLEAR MAGNETIC RESONANCE; REPRODUCIBILITY; ULTRAVIOLET SPECTROSCOPY;

EID: 4644353729     PISSN: 03855414     EISSN: None     Source Type: Journal    
DOI: 10.3987/com-04-10124     Document Type: Article

References (15)

1. J. P. Dunn, D. M. Green, P. H. Nelson, A. J. Rooks, A. Tomolonis, and K. G. Untch, J. Med. Chem., 1977, 20, 1557.
2. J. Ackrell, Y. Antonio, F. Franco, R. Landeros, A. León, J. M. Muchowski, M. L. Maddox, P. H. Nelson, W. H. Rooks, A. P. Roskowski, and M. B. Wallach, J. Med. Chem., 1978, 21, 1035.
3. J. P. Dunn, J. M. Muchowski, M. L. Maddox, and P. H. Nelson, J. Med. Chem., 1981, 24, 1097.
4. S. A. Berkowitz, G. Bernhard, P. J. Bilka, J. M. Marchesano, M. Rosenthal, and G. F. Wortham, Curr. Ther. Res., 1974, 16, 442.
5. "Zomepirac: A new Non-Narcotic Analgesic"; Proccedings of the symposium on Zomepirac; Atlanta, G. A, 1979, J. Clin. Pharmacol., 1980, 20, 213.
6. J. R. Carson and S. J. Wong, J. Med. Chem., 1973, 16, 172.
7. F. Franco, R. Greenhouse, and J. M. Muchowski, J. Org. Chem., 1982, 47, 1682.
8. J. Yee, C. R. Brown, H. Sevelius, and V. Wild, Clin. Pharmacol. Ther., 1984, 35, 285.
9. S. S. Bloomfield, J. Mitchell, G. Cissell, and T. Barden, Clin. Pharmacol. Ther., 1984, 85, 228.10
10. R. W. Ward and A. C. Goudie, European Patent Application 0049999 A2, (Chem. Abstr., 1983, 99, 122288).
11. V. Fiandanese, G. Marchese, V. Martina, and L. Ronzini, Tetrahedron Lett., 1984, 25, 4805.
12. T. K. Ross, H. M. Dali, and W. G. Tsang, Tetrahedron Lett., 1977, 3859.
13. J. B. Doherty, U. S. Patent, 1985, 4, 496, 741, (Chem. Abstr., 1985, 102, 166728).
14. H. Carpio, E. Galeazzi, R. Greenhouse, A. Guzmán, E. Velarde, Y. Antonio, F. Franco, A. León, V. Pérez, R. Salas, D. Valdé, J. Ackrell, D. Cho, P. Gallegra, O. Halpern, R. Koehler, M. L. Maddox, J. M. Muchowski, A. Prince, D. Tegg, T. Craig Thyrber, A. R. van Horn, and D. Wren, J. Can. Chem., 1982, 60, 2295.
15. A. Covarrubias-Zúñiga, J. G. Avila-Zárraga, and D. Arias Salas, Synth. Commun., 2003, 33, 3173.