Cardiac Diseases

Stroke: Pathophysiology, Diagnosis, and Management

Volumn , Issue , 2004, Pages 747-759

  Furie, Karen L ^a,b   Homma, Shunichi ^c,d   Kistler, J Philip ^b  

^a HARVARD MEDICAL SCHOOL   (United States)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

^c New York Presbyterian Columbia University Medical Center   (United States)

^d Department of Orthopaedic Surgery   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 4644353468     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1016/B0-44-306600-0/50042-0     Document Type: Chapter

References (175)

1. Sacco RL, et al. Infarcts of undetermined cause: The NINCDS Stroke Data Bank. Ann Neurol 1989, 25:382-390.
2. Kannel WB, et al. Prevalence, incidence, prognosis, and predisposing conditions for atrial fibrillation: Population-based estimates. Am J Cardiol 1998, 82:2N-9N.
3. Wolf PA, et al. Epidemiologic assessment of chronic atrial fibrillation and risk of stroke: The Framingham study. Neurology 1978, 28:973-977.
4. Wolf PA, Abbott RD, Kannel WB Atrial fibrillation: A major contributor to stroke in the elderly. The Framingham Study. Arch Intern Med 1987, 147:1561-1564.
5. Kittner SJ, et al. Cerebral infarction in young adults: The Baltimore-Washington Cooperative Young Stroke Study. Neurology 1998, 50:890-894.
6. Adams HP, et al. Nonhemorrhagic cerebral infarction in young adults. Arch Neurol 1986, 4:793-796.
7. Cardiogenic brain embolism Cerebral Embolism Task Force. Arch Neurol 1986, 43:71-84.
8. American Heart Association Heart and Stroke Facts: Statistical Supplement 1999, American Heart Association, Dallas.
9. Diringer MN, et al. Predictors of acute hospital costs for treatment of ischemic stroke in an academic center. Stroke 1999, 30:724-728.
10. Arboix A, et al. Cardioembolic infarction in the Sagrat Cor-Alianza Hospital of Barcelona Stroke Registry. Acta Neurol Scand 1997, 96:407-412.
11. Petty GW, et al. Ischemic stroke subtypes: A population-based study of functional outcome, survival, and recurrence. Stroke 2000, 31:1062-1068.
12. Horowitz DR, et al. Mechanisms in lacunar infarction. Stroke 1992, 23:325-327.
13. Staaf G, et al. Sensorimotor stroke: Clinical features, MRI findings, and cardiac and vascular concomitants in 32 patients. Acta Neurol Scand 1998, 97:93-98.
14. Ramirez-Lassepas M, et al. Can embolic stroke be diagnosed on the basis of neurologic clinical criteria?. Arch Neurol 1987, 44:87-89.
15. Caplan LR, Hier DB, D'Cruz I Cerebral embolism in the Michael Reese Stroke Registry. Stroke 1983, 14:530-536.
16. Foulkes MA, et al. The Stroke Data Bank: Design, methods, and baseline characteristics. Stroke 1988, 19:547-554.
17. Bogousslavsky J, et al. Cardiac sources of embolism and cerebral infarction-clinical consequences and vascular concomitants: The Lausanne Stroke Registry. Neurology 1991, 41:855-859.
18. Appen RE, Wray SH, Cogan DG Central retinal artery occlusion. Am J Ophthalmol 1975, 79:374-381.
19. Babikian VL, et al. Cerebral microembolism and early recurrent cerebral or retinal ischemic events. Stroke 1997, 28:1314-1318.
20. Hankey GJ, Slattery JM, Warlow CP Prognosis and prognostic factors of retinal infarction: A prospective cohort study. BMJ 1991, 302:499-504.
21. Babikian VL, et al. Clinical correlates of high-intensity transient signals detected on transcranial Doppler sonography in patients with cerebrovascular disease. Stroke 1994, 25:1570-1573.
22. Murkin JM Etiology and incidence of brain dysfunction after cardiac surgery. J Cardiothorac Vasc Anesth 1999, 13(Suppl 1):12-77. discussion 36-37.
23. Gacs G, Merei FT, Bodosi M Balloon catheter as a model of cerebral emboli in humans. Stroke 1982, 13:39-42.
24. Cardiogenic brain embolism The second report of the Cerebral Embolism Task Force. Arch Neurol 1989, 46:727-743.
25. Timsit SG, et al. Brain infarction severity differs according to cardiac or arterial embolic source. Neurology 1993, 43:728-733.
26. Fisher CM, Pearlman A The nonsudden onset of cerebral embolism. Neurology 1967, 17:1025-1032.
27. Kraus JA, Berlit P Cerebral embolism and epileptic seizures: The role of the embolic source. Acta Neurol Scand 1998, 97:154-159.
28. Minematsu K, Yamaguchi T, Omae T 'Spectacular shrinking deficit': Rapid recovery from a major hemispheric syndrome by migration of an embolus. Neurology 1992, 42:157-162.
29. Kittner SJ, et al. Features on initial computed tomography scan of infarcts with a cardiac source of embolism in the NINDS Stroke Data Bank. Stroke 1992, 23:1748-1751.
30. Ringelstein EB, et al. Computed tomographic patterns of proven embolic brain infarctions. Ann Neurol 1989, 26:759-765.
31. Bogousslavsky J, Bernasconi A, Kumral E Acute multiple infarction involving the anterior circulation. Arch Neurol 1996, 53:50-57.
32. Bogousslavsky J, et al. Pathogenesis of anterior circulation stroke in patients with nonvalvular atrial fibrillation: The Lausanne Stroke Registry. Neurology 1990, 40:1046-1050.
33. Horowitz DR, Tuhrim S Stroke mechanisms and clinical presentation in large subcortical infarctions. Neurology 1997, 49:1538-1541.
34. Bogousslavsky J, Van Melle G, Regli F Middle cerebral artery pial territory infarcts: A study of the Lausanne Stroke Registry. Ann Neurol 1989, 25:555-560.
35. Yamamoto Y, et al. Posterior cerebral artery territory infarcts in the New England Medical Center Posterior Circulation Registry. Arch Neurol 1999, 56:824-832.
36. Pessin MS, et al. Clinical features and mechanism of occipital infarction. Ann Neurol 1987, 21:290-299.
37. Hart RG, Easton JD Hemorrhagic infarcts. Stroke 1986, 17:586-589.
38. Mast H, et al. Cardiac sources of embolism in patients with pial artery infarcts and lacunar lesions. Stroke 1994, 25:776-781.
39. Rem JA, et al. Value of cardiac monitoring and echocardiography in TIA and stroke patients. Stroke 1985, 16:950-956.
40. Bogousslavsky J, et al. Cardiac and arterial lesions in carotid transient ischemic attacks. Arch Neurol 1986, 43:223-228.
41. Moncayo J, et al. Coexisting causes of ischemic stroke. Arch Neurol 2000, 57:1139-1144.
42. Hornig CR, et al. Specific cardiological evaluation after focal cerebral ischemia. Acta Neurol Scand 1996, 93:297-302.
43. Bogousslavsky J, et al. The etiology of posterior circulation infarcts: A prospective study using magnetic resonance imaging and magnetic resonance angiography. Neurology 1993, 43:1528-1533.
44. Pop GA, et al. Predictive value of clinical history and electrocardiogram in patients with transient ischemic attack or minor ischemic stroke for subsequent cardiac and cerebral ischemic events. The Dutch TIA Trial Study Group. Arch Neurol 1994, 51:333-341.
45. Popp RL Echocardiography (2). N Engl J Med 1990, 323:165-172.
46. Popp RL Echocardiography (1). N Engl J Med 1990, 323:101-109.
47. Pop G, et al. Transesophageal echocardiography in the detection of intracardiac embolic sources in patients with transient ischemic attacks. Stroke 1990, 21:560-565.
48. Hata JS, et al. Impact of transesophageal echocardiography on the anticoagulation management of patients admitted with focal cerebral ischemia. Am J Cardiol 1993, 72:707-710.
49. Pearson AC, et al. Superiority of transesophageal echocardiography in detecting cardiac source of embolism in patients with cerebral ischemia of uncertain etiology. J Am Coll Cardiol 1991, 17:66-72.
50. Warner MF, Momah KI Routine transesophageal echocardiography for cerebral ischemia: Is it really necessary?. Arch Intern Med 1996, 156:1719-1723.
51. McNamara RL, et al. Echocardiographic identification of cardiovascular sources of emboli to guide clinical management of stroke: A cost-effectiveness analysis. Ann Intern Med 1997, 127:775-787.
52. Sliwka U, et al. Occurrence of transcranial Doppler high-intensity transient signals in patients with potential cardiac sources of embolism: A prospective study. Stroke 1995, 26:2067-2070.
53. Tong DC, Bolger A, Albers GW Incidence of transcranial Dopplerdetected cerebral microemboli in patients referred for echocardiography. Stroke 1994, 25:2138-2141.
54. Berge E, et al. Low molecular-weight heparin versus aspirin in patients with acute ischaemic stroke and atrial fibrillation: A double-blind randomised study. HAEST Study Group. Heparin in Acute Embolic Stroke Trial. Lancet 2000, 355:1205-1210.
55. del Zoppo GJ Antithrombotic treatments in acute ischemic stroke. Curr Opin Hematol 2000, 7:309-315.
56. Mohr JP, et al. A comparison of warfarin and aspirin for the prevention of recurrent ischemic stroke. N Engl J Med 2001, 345:1444-1451.
57. Katz SD, et al. Low incidence of stroke in ambulatory patients with heart failure: A prospective study. Am Heart J 1993, 126:141-146.
58. Fuster V, et al. The natural history of idiopathic dilated cardiomyopathy. Am J Cardiol 1981, 47:525-531.
59. Pullicino PM, Halperin JL, Thompson JL Stroke in patients with heart failure and reduced left ventricular ejection fraction. Neurology 2000, 54:288-294.
60. Loh E, et al. Ventricular dysfunction and the risk of stroke after myocardial infarction. N Engl J Med 1997, 336:251-257.
61. Cleland JG Anticoagulant and antiplatelet therapy in heart failure. Curr Opin Cardiol 1997, 12:276-287.
62. Dries DL, et al. Ejection fraction and risk of thromboembolic events in patients with systolic dysfunction and sinus rhythm: Evidence for gender differences in the studies of left ventricular dysfunction trials. J Am Coll Cardiol 1997, 29:1074-1080.
63. Kannel WB, Wolf PA, Verter J Manifestations of coronary disease predisposing to stroke. The Framingham study. JAMA 1983, 250:2942-2946.
64. Segal JP, et al. Idiopathic cardiomyopathy: Clinical features, prognosis and therapy. Curr Probl Cardiol 1978, 3:1-48.
65. Effect of long-term oral anticoagulant treatment on mortality and cardiovascular morbidity after myocardial infarction Anticoagulants in the Secondary Prevention of Events in Coronary Thrombosis (ASPECT) Research Group. Lancet 1994, 343:499-503.
66. Smith P, Arnesen H, Holme I The effect of warfarin on mortality and reinfarction after myocardial infarction. N Engl J Med 1990, 323:147-152.
67. A double-blind trial to assess long-term oral anticoagulant therapy in elderly patients after myocardial infarction Report of the Sixty Plus Reinfarction Study Research Group. Lancet 1980, 2:989-994.
68. Komrad MS, et al. Myocardial infarction and stroke. Neurology 1984, 34:1403-1409.
69. Puletti M, et al. Incidence of systemic thromboembolic lesions in acute myocardial infarction. Clin Cardiol 1986, 9:331-333.
70. Asinger RW, et al. Incidence of left-ventricular thrombosis after acute transmural myocardial infarction: Serial evaluation by two-dimensional echocardiography. N Engl J Med 1981, 305:297-302.
71. Stratton JR, Resnick AD Increased embolic risk in patients with left ventricular thrombi. Circulation 1987, 75:1004-1011.
72. Derex L, et al. Thrombolytic therapy in acute ischemic stroke patients with cardiac thrombus. Neurology 2001, 57:2122-2125.
73. Hurlen M, Abdelnoor M, Smith P, et al. Warfarin, aspirin, or both after myocardial infarction. N Engl J Med 2002, 347:969-974.
74. Sacco RL, Homma S, Di Tullio MR Patent foramen ovale: A new risk factor for ischemic stroke. Heart Dis Stroke 1993, 2:235-241.
75. Di Tullio M, et al. Patent foramen ovale as a risk factor for cryptogenic stroke. Ann Intern Med 1992, 117:461-465.
76. Steiner MM, et al. Patent foramen ovale size and embolic brain imaging findings among patients with ischemic stroke. Stroke 1998, 29:944-948.
77. Barinagarrementeria F, Amaya LE, Cantu C Causes and mechanisms of cerebellar infarction in young patients. Stroke 1997, 28:2400-2404.
78. Hanna JP, et al. Patent foramen ovale and brain infarct: Echocardiographic predictors, recurrence, and prevention. Stroke 1994, 25:782-786.
79. Mas JL, et al. Recurrent cerebrovascular events associated with patent foramen ovale, atrial septal aneurysm, or both. N Engl J Med 2001, 345:1740-1746.
80. Homma S, et al. Characteristics of patent foramen ovale associated with cryptogenic stroke: A biplane transesophageal echocardiographic study. Stroke 1994, 25:582-586.
81. Schuchlenz HW, et al. The association between the diameter of a patent foramen ovale and the risk of embolic cerebrovascular events. Am J Med 2000, 109:456-462.
82. Homma S, Sacco RL, Di Tullio MR, et al. Effect of medical treatment in stroke patients with patent foramen ovale: Patent foramen ovale in Cryptogenic Stroke Study. Circulation 2002, 105:2625-2631.
83. Hausmann D, et al. Diagnosis of patent foramen ovale by transesophageal echocardiography and association with cerebral and peripheral embolic events. Am J Cardiol 1992, 70:668-672.
84. Lethen H, et al. Frequency of deep vein thrombosis in patients with patent foramen ovale and ischemic stroke or transient ischemic attack. Am J Cardiol 1997, 80:1066-1069.
85. Schuchlenz HW, et al. Transesophageal echocardiography for quantifying size of patent foramen ovale in patients with cryptogenic cerebrovascular events. Stroke 2002, 33:293-296.
86. Hung J, et al. Closure of patent foramen ovale for paradoxical emboli: Intermediate-term risk of recurrent neurological events following transcatheter device placement. J Am Coll Cardiol 2000, 35:1311-1316.
87. Sandok BA, von Estorff I, Giuliani ER CNS embolism due to atrial myxoma: Clinical features and diagnosis. Arch Neurol 1980, 37:485-488.
88. Roeltgen DP, Weimer GR, Patterson LF Delayed neurologic complications of left atrial myxoma. Neurology 1981, 31:8-13.
89. Zotz RJ, et al. Spontaneous echo contrast caused by platelet and leukocyte aggregates?. Stroke 2001, 32:1127-1133.
90. Peverill RE, et al. Haematologic determinants of left atrial spontaneous echo contrast in mitral stenosis. Int J Cardiol 2001, 81:235-242.
91. Castello R, Pearson AC, Labovitz AJ Prevalence and clinical implications of atrial spontaneous contrast in patients undergoing transesophageal echocardiography. Am J Cardiol 1990, 65:1149-1153.
92. Daniel WG, et al. Left atrial spontaneous echo contrast in mitral valve disease: An indicator for an increased thromboembolic risk. J Am Coll Cardiol 1988, 11:1204-1211.
93. Castello R, et al. Spontaneous echocardiographic contrast in the descending aorta. Am Heart J 1990, 120:915-919.
94. Comess KA, et al. Transesophageal echocardiography and carotid ultrasound in patients with cerebral ischemia: Prevalence of findings and recurrent stroke risk. J Am Coll Cardiol 1994, 23:1598-1603.
95. Tice FD, et al. Mitral valve strands in patients with focal cerebral ischemia. Stroke 1996, 27:1183-1186.
96. Freedberg RS, et al. Valve strands are strongly associated with systemic embolization: A transesophageal echocardiographic study. J Am Coll Cardiol 1995, 26:1709-1712.
97. Orsinelli DA, Pearson AC Detection of prosthetic valve strands by transesophageal echocardiography: Clinical significance in patients with suspected cardiac source of embolism. J Am Coll Cardiol 1995, 26:1713-1718.
98. Roberts JK, et al. Valvular strands and cerebral ischemia: Effect of demographics and strand characteristics. Stroke 1997, 28:2185-2188.
99. Risk factors for stroke and efficacy of antithrombotic therapy in atrial fibrillation Analysis of pooled data from five randomized controlled trials. Arch Intern Med 1994, 154:1449-1457.
100. Warfarin versus aspirin for prevention of thromboembolism in atrial fibrillation Stroke Prevention in Atrial Fibrillation II Study. Lancet 1994, 343:687-691.
101. Adjusted-dose warfarin versus low-intensity, fixed-dose warfarin plus aspirin for high-risk patients with atrial fibrillation Stroke Prevention in Atrial Fibrillation III randomised clinical trial. Lancet 1996, 348:633-638.
102. Patients with nonvalvular atrial fibrillation at low risk of stroke during treatment with aspirin Stroke Prevention in Atrial Fibrillation III Study. The SPAF III Writing Committee for the Stroke Prevention in Atrial Fibrillation Investigators. JAMA 1998, 279:1273-1277.
103. The effect of low-dose warfarin on the risk of stroke in patients with nonrheumatic atrial fibrillation The Boston Area Anticoagulation Trial for Atrial Fibrillation Investigators. N Engl J Med 1990, 323:1505-1511.
104. Stroke Prevention in Atrial Fibrillation Study Final results. Circulation 1991, 84:527-539.
105. Secondary prevention in non-rheumatic atrial fibrillation after transient ischaemic attack or minor stroke EAFT (European Atrial Fibrillation Trial) Study Group. Lancet 1993, 342:1255-1262.
106. Nabavi DG, et al. Absence of circulating microemboli in patients with lone atrial fibrillation. Neurol Res 1999, 21:566-568.
107. Albers GW, et al. Clinical characteristics and management of acute stroke in patients with atrial fibrillation admitted to US university hospitals. Neurology 1997, 48:1598-1604.
108. Asinger RW Role of transthoracic echocardiography in atrial fibrillation. Echocardiography 2000, 17:357-364.
109. Egeblad H, et al. Role of echocardiography in systemic arterial embolism: A review with recommendations. Scand Cardiovasc J 1998, 32:323-342.
110. Predictors of thromboembolism in atrial fibrillation II: Echocardiographic features of patients at risk. The Stroke Prevention in Atrial Fibrillation Investigators. Ann Intern Med 1992, 116:6-12.
111. Echocardiographic predictors of stroke in patients with atrial fibrillation A prospective study of 1066 patients from 3 clinical trials. Arch Intern Med 1998, 158:1316-1320.
112. Abe Y, et al. Prediction of embolism in atrial fibrillation: Classification of left atrial thrombi by transesophageal echocardiography. Jpn Circ J 2000, 64:411-415.
113. Fagan SM, Chan KL Transesophageal echocardiography risk factors for stroke in nonvalvular atrial fibrillation. Echocardiography 2000, 17:365-372.
114. Transesophageal echocardiographic correlates of thromboembolism in high-risk patients with nonvalvular atrial fibrillation The Stroke Prevention in Atrial Fibrillation Investigators Committee on Echocardiography. Ann Intern Med 1998, 128:639-647.
115. Babikian VL, et al. Intracerebral hemorrhage in stroke patients anticoagulated with heparin. Stroke 1989, 20:1500-1503.
116. Rothrock JF, et al. Acute anticoagulation following cardioembolic stroke. Stroke 1989, 20:730-734.
117. Bogousslavsky J, Regli F Anticoagulant-induced intracerebral bleeding in brain ischemia: Evaluation in 200 patients with TIAs, emboli from the heart, and progressing stroke. Acta Neurol Scand 1985, 71:464-471.
118. Lodder J, van der Lugt PJ Evaluation of the risk of immediate anticoagulant treatment in patients with embolic stroke of cardiac origin. Stroke 1983, 14:42-46.
119. Stoddard MF Risk of thromboembolism in acute atrial fibrillation or atrial flutter. Echocardiography 2000, 17:393-405.
120. Rubenstein JJ, et al. Clinical spectrum of the sick sinus syndrome. Circulation 1972, 46:5-13.
121. Fairfax AJ, Lambert CD, Leatham A Systemic embolism in chronic sinoatrial disorder. N Engl J Med 1976, 295:190-192.
122. Fairfax AJ, Lambert CD Neurological aspects of sinoatrial heart block. J Neurol Neurosurg Psychiatry 1976, 39:576-580.
123. Santini M, et al. Relation of prognosis in sick sinus syndrome to age, conduction defects and modes of permanent cardiac pacing. Am J Cardiol 1990, 65:729-735.
124. Biblo LA, et al. Risk of stroke in patients with atrial flutter. Am J Cardiol 2001, 87:346-349.
125. Santiago D, et al. Left atrial appendage function and thrombus formation in atrial fibrillation-flutter: A transesophageal echocardiographic study. J Am Coll Cardiol 1994, 24:159-164.
126. Nair CK, et al. Long-term follow-up of patients with echocardiographically detected mitral annular calcium and comparison with age- and sex-matched control subjects. Am J Cardiol 1989, 63:465-470.
127. Nishide M, et al. Cardiac abnormalities in ischemic cerebrovascular disease studied by two-dimensional echocardiography. Stroke 1983, 14:541-545.
128. de Bono DP, Warlow CP Mitral-annulus calcification and cerebral or retinal ischaemia. Lancet 1979, 2:383-385.
129. Chesebro JH, Adams PC, Fuster V Antithrombotic therapy in patients with valvular heart disease and prosthetic heart valves. J Am Coll Cardiol 1986, 8(Suppl B):41B-56B.
130. Kuntze CE, et al. Rates of thromboembolism with three different mechanical heart valve prostheses: randomised study. Lancet 1989, 1:514-517.
131. Kuntze CE, Blackstone EH, Ebels T Thromboembolism and mechanical heart valves: A randomized study revisited. Ann Thorac Surg 1998, 66:101-117.
132. Olesen KH, et al. Long-term follow-up in 185 patients after mitral valve replacement with the Lillehei-Kaster prosthesis: Overall results and prosthesis-related complications. Eur Heart J 1987, 8:680-688.
133. Turpie AG, et al. A comparison of aspirin with placebo in patients treated with warfarin after heart-valve replacement. N Engl J Med 1993, 329:524-529.
134. Coulshed N, et al. Systemic embolism in mitral valve disease. Br Heart J 1970, 32:26-34.
135. Szekely P Systemic embolism and anticoagulant prophylaxis in rheumatic heart disease. BMJ 1964, 1:1209-1212.
136. Szekely P Rheumatic heart disease in three decades (1942-1971). Singapore Med J 1973, 14:417-419.
137. Salgado AV, et al. Neurologic complications of endocarditis: A 12-year experience. Neurology 1989, 39:173-178.
138. Hart RG, et al. Stroke in infective endocarditis. Stroke 1990, 21:695-700.
139. Pruitt AA, et al. Neurologic complications of bacterial endocarditis. Medicine (Baltimore) 1978, 57:329-343.
140. Karchmer AW Infective endocarditis. Harrison's Principles of Internal Medicine 2001, McGraw-Hill, New York. 15th ed. E. Braunwald, A.S. Fauci, D.L. Kasper (Eds.).
141. Buda AJ, et al. Prognostic significance of vegetations detected by two-dimensional echocardiography in infective endocarditis. Am Heart J 1986, 112:1291-1296.
142. Salgado AV, Furlan AJ, Keys TF Mycotic aneurysm, subarachnoid hemorrhage, and indications for cerebral angiography in infective endocarditis. Stroke 1987, 18:1057-1060.
143. Lopez JA, et al. Nonbacterial thrombotic endocarditis: A review. Am Heart J 1987, 113:773-784.
144. Rogers LR, et al. Cerebral infarction from non-bacterial thrombotic endocarditis: Clinical and pathological study including the effects of anticoagulation. Am J Med 1987, 83:746-756.
145. Lopez JA, Fishbein MC, Siegel RJ Echocardiographic features of nonbacterial thrombotic endocarditis. Am J Cardiol 1987, 59:478-480.
146. Futrell N, Millikan C Frequency, etiology, and prevention of stroke in patients with systemic lupus erythematosus. Stroke 1989, 20:583-591.
147. Gorelick PB, et al. Embolic stroke complicating systemic lupus erythematosus. Arch Neurol 1985, 42:813-815.
148. Pomerance A Cardiac pathology and systolic murmurs in the elderly. Br Heart J 1968, 30:687-689.
149. Pomerance A Cardiac pathology in the aged. Geriatrics 1968, 23:101-114.
150. Kapila A, Hart R Calcific cerebral emboli and aortic stenosis: Detection of computed tomography. Stroke 1986, 17:619-621.
151. Gilon D, et al. Lack of evidence of an association between mitral-valve prolapse and stroke in young patients. N Engl J Med, 1999, 341:8-13.
152. Cesena FH, et al. Papillary fibroelastoma of the mitral valve 12 years after mitral valve commissurotomy. South Med J 1999, 92:1023-1028.
153. Muir KW, et al. Visualization of cardiac emboli from mitral valve papillary fibroelastoma. Stroke 1996, 27:1133-1134.
154. Kasarskis EJ, O'Connor W, Earle G Embolic stroke from cardiac papillary fibroelastomas. Stroke 1988, 19:1171-1173.
155. Roach GW, et al. Adverse cerebral outcomes after coronary bypass surgery. Multicenter Study of Perioperative Ischemia Research Group and the Ischemia Research and Education Foundation Investigators. N Engl J Med 1996, 335:1857-1863.
156. Barbut D, Caplan LR Brain complications of cardiac surgery. Curr Probl Cardiol 1997, 22:449-480.
157. Salazar JD, et al. Stroke after cardiac surgery: Short- and long-term outcomes. Ann Thorac Surg 2001, 72:1195-1201. discussion1201-1202.
158. Hogue CW, et al. Risk factors for early or delayed stroke after cardiac surgery. Circulation 1999, 100:642-647.
159. Newman MF, et al. Multicenter preoperative stroke risk index for patients undergoing coronary artery bypass graft surgery. Multicenter Study of Perioperative Ischemia (McSPI) Research Group. Circulation 1996, 94(Suppl):II74-II80.
160. Stamou SC, Corso PJ Coronary revascularization without cardiopulmonary bypass in high-risk patients: A route to the future. Ann Thorac Surg 2001, 71:1056-1061.
161. Wityk RJ, et al. Diffusion- and perfusion-weighted brain magnetic resonance imaging in patients with neurologic complications after cardiac surgery. Arch Neurol 2001, 58:571-576.
162. Barbut D, et al. Posterior distribution of infarcts in strokes related to cardiac operations. Ann Thorac Surg 1998, 65:1656-1659.
163. Segal AZ, et al. Stroke as a complication of cardiac catheterization: Risk factors and clinical features. Neurology 2001, 56:975-977.
164. Jackson JL, Meyer GS, Pettit T Complications from cardiac catheterization: Analysis of a military database. Mil Med 2000, 165:298-301.
165. Lip GY, et al. Fibrin D-dimer and beta-thromboglobulin as markers of thrombogenesis and platelet activation in atrial fibrillation: Effects of introducing ultra-low-dose warfarin and aspirin. Circulation 1996, 94:425-431.
166. Lip GY, et al. Fibrinogen and fibrin D-dimer levels in paroxysmal atrial fibrillation: Evidence for intermediate elevated levels of intravascular thrombogenesis. Am Heart J 1996, 131:724-730.
167. Lip GY, et al. Plasma fibrinogen and fibrin D-dimer in patients with atrial fibrillation: Effects of cardioversion to sinus rhythm. Int J Cardiol 1995, 51:245-251.
168. Lip GY, et al. Increased markers of thrombogenesis in chronic atrial fibrillation: Effects of warfarin treatment. Br Heart J 1995, 73:527-533.
169. Gustafsson C, et al. Coagulation factors and the increased risk of stroke in nonvalvular atrial fibrillation. Stroke 1990, 21:47-51.
170. Mitusch R, et al. Detection of a hypercoagulable state in nonvalvular atrial fibrillation and the effect of anticoagulant therapy. Thromb Haemost 1996, 75:219-223.
171. Rosenberg RD, Aird WC Vascular-bed-specific hemostasis and hypercoagulable states. N Engl J Med 1999, 340:1555-1564.
172. Kistler JP, et al. Effect of low-intensity warfarin anticoagulation on level of activity of the hemostatic system in patients with atrial fibrillation. BAATAF Investigators. Stroke 1993, 24:1360-1365.
173. Lip GY, et al. Effects of warfarin therapy on plasma fibrinogen, von Willebrand factor, and fibrin D-dimer in left ventricular dysfunction secondary to coronary artery disease with and without aneurysms. Am J Cardiol 1995, 76:453-458.
174. Yamamoto K, et al. Coagulation activity is increased in the left atrium of patients with mitral stenosis. J Am Coll Cardiol 1995, 25:107-112.
175. Jafri SM, et al. Platelet function, thrombin and fibrinolytic activity in patients with heart failure. Eur Heart J 1993, 14:205-212.