Objective measurements of corneal light-backscatter during corneal swelling, by optical coherence tomography

Investigative Ophthalmology and Visual Science

Volumn 45, Issue 10, 2004, Pages 3493-3498

  Wang, Jianhua ^a,b   Simpson, Trefford L ^a   Fonn, Desmond ^a  

^a UNIVERSITY OF WATERLOO   (Canada)

^b UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ARTICLE; CLINICAL ARTICLE; COMPUTER PROGRAM; CORNEA; CORNEA EDEMA; CORNEA THICKNESS; CORRELATION ANALYSIS; EYELID CLOSURE; FEMALE; HUMAN; LIGHT; MALE; MEASUREMENT; OPTICAL COHERENCE TOMOGRAPHY; PRIORITY JOURNAL; RADIATION SCATTERING; RANDOMIZATION; REPRODUCIBILITY; SOFT CONTACT LENS; STATISTICAL SIGNIFICANCE;

ADULT; CONTACT LENSES, HYDROPHILIC; CORNEA; CORNEAL EDEMA; DIAGNOSTIC TECHNIQUES, OPHTHALMOLOGICAL; FEMALE; HUMANS; LIGHT; MALE; PROSPECTIVE STUDIES; SCATTERING, RADIATION; TOMOGRAPHY, OPTICAL COHERENCE;

EID: 4644352714     PISSN: 01460404     EISSN: None     Source Type: Journal    
DOI: 10.1167/iovs.04-0096     Document Type: Article

References (61)

1. Lohmann CP, Fitzke F, O'Brart D, Muir MK, Timberlake G, Marshall J. Corneal light scattering and visual performance in myopic individuals with spectacles, contact lenses, or excimer laser photorefractive keratectomy. Am J Ophthalmol. 1993;115:444-453.
2. Holden R, Shun-Shin GA, Brown NA. Central corneal light scatter in long-term diabetics. Am J Optom Physiol Opt. 1994;8:44-45.
3. Griffiths SN, Drasdo N, Barnes DA, Sabell AG. Effect of epithelial and stromal edema on the light scattering properties of the cornea. Am J Optom Physiol Opt. 1986;63:888-894.
4. Møller-Pedersen T, Cavanagh HD, Petroll WM, Jester JV. Stromal wound healing explains refractive instability and haze development after photorefractive keratectomy: a 1-year confocal microscopic study. Ophthalmology. 2000;107:1235-1245.
5. Møller-Pedersen T, Vogel M, Li HF, Petroll WM, Cavanagh HD, Jester JV. Quantification of stromal thinning, epithelial thickness, and corneal haze after photorefractive keratectomy using in vivo confocal microscopy. Ophthalmology. 1997;104:360-368.
6. Olsen T. Light scattering from the human cornea. Invest Ophthalmol Vis Sci. 1982;23:81-86.
7. Braunstein RE, Jain S, McCally RL, Stark WJ, Connolly PJ, Azar DT. Objective measurement of corneal light scattering after excimer laser keratectomy. Ophthalmology. 1996;103:439-443.
8. Maldonado M, Arnau V, Martinez-Costa R, et al. Reproducibility of digital image analysis for measuring corneal haze after myopic PRK. Am J Ophthalmol. 1997;123:31-4l.
9. Maldonado MJ, Arnau V, Navea A, et al. Direct objective quantification of corneal haze after excimer laser photorefractive keratectomy for high myopia. Ophthalmology. 1996;103:1970-1978.
10. Lohmann C, Timberlake GT, Fitzke F, Gartry D, Muir MK, Marshall J. Corneal light scattering after excimer laser photorefractive keratectomy: the objective measurement of haze. Refract Corneal Surg. 1992;8:114-121.
11. Fantes FE, Hanna KD, Waring GO, Pouliquen Y, Thompson KP, Savoldelli M. Wound healing after excimer laser keratomileusis (photorefractive keratectomy) in monkeys. Arch Ophthalmol. 1990;108:665-675.
12. Kikkawa Y, Hirayama K. Uneven swelling of the corneal stroma. Invest Ophthalmol. 1970;9:735-741.
13. Allemann N, Chamon W, Silverman RH, et al. High-frequency ultrasound quantitative analyses of corneal scarring following excimer laser keratectomy. Arch Ophthalmol. 1993;111:968-973.
14. Binder PS, Bosem M, Weinreb RN. Scheimpflug anterior segment photography assessment of wound healing after myopic excimer laser photorefractive keratectomy. J Cataract Refract Surg. 1996;22:205-212.
15. Møller-Pedersen T, Cavanagh HD, Petroll WM, Jester JV. Corneal haze development after PRK is regulated by volume of stromal tissue removal. Cornea. 1998;17:627-639.
16. Izatt JA, Hee MR, Swanson EA, et al. Micrometer-scale resolution imaging of the anterior eye in vivo with optical coherence tomography. Arch Ophthalmol. 1994;112:1584-1589.
17. Huang Y, Cideciyan AV, Papastergiou GI, et al. Relation of optical coherence tomography to microanatomy in normal and rd chickens. Invest Ophthalmol Vis Sci. 1998;39:2405-2416.
18. Wang J, Fonn D, Simpson TL, Jones L. The measurement of corneal epithelial thickness in response to hypoxia using optical coherence tomography. Am J Ophthalmol. 2002;133:315-319.
19. Wang J, Fonn D, Simpson TL, Sorbara L, Kort R, Jones L. Topographical thickness of the epithelium and total cornea after overnight wear of reverse-geometry rigid contact lenses for myopia reduction. Invest Ophthalmol Vis Sci. 2003;44:4742-4746.
20. Wang J, Fonn D, Simpson TL. Topographical thickness of the epithelium and total cornea after hydrogel and PMMA contact lens wear with eye closure. Invest Ophthalmol Vis Sci. 2003;44:1070-1074.
21. Wang J, Fonn D, Simpson TL, Jones L. Precorneal and pre- and postlens tear film thickness measured indirectly with optical coherence tomography. Invest Ophthalmol Vis Sci. 2003;44:2524-2528.
22. Wang J, Fonn D, Simpson TL, Jones L. Relation between optical coherence tomography and optical pachymetry measurements of corneal swelling induced by hypoxia. Am J Ophthalmol. 2002;134:93-98.
23. Maldonado MJ, Ruiz-Oblitas L, Munuera JM, Aliseda D, Garcia-Layana A, Moreno-Montanes J. Optical coherence tomography evaluation of the corneal cap and stromal bed features after laser in situ keratomileusis for high myopia and astigmatism. Ophthalmology. 2000;107:81-87.
24. Feng Y, Varikooty J, Simpson TL. Diurnal variation of corneal and corneal epithelial thickness measured using optical coherence tomography. Cornea. 2001;20:480-483.
25. Wirbelauer C, Scholz C, Haberle H, Laqua H, Pham DT. Corneal optical coherence tomography before and after phototherapeutic keratectomy for recurrent epithelial erosions. J Cataract Refract Surg. 2002;28:1629-1635.
26. Beems E, van Best JA. Light transmission of the cornea in whole human eyes. Exp Eye Res. 1990;50:393-396.
27. Freegard T. The physical basis of transparency of the normal cornea. Am J Optom Physiol Opt. 1997;11:465-471.
28. Klyce SD, Russell SR. Numerical solution of coupled transport equations applied to corneal hydration dynamics. J Physiol. 1979;292:107-134.
29. Komai Y, Ushiki T. The three-dimensional organization of collagen fibrils in the human cornea and sclera. Invest Ophthalmol Vis Sci. 1991;32:2244-2258.
30. Castoro JA, Bettelheim AA, Bettelheim FA. Water gradients across bovine cornea. Invest Ophthalmol Vis Sci. 1988;29:963-968.
31. Fisher BT, Masiello KA, Goldstein MH, Hahn DW. Assessment of transient changes in corneal hydration using confocal Raman spectroscopy. Cornea. 2003;22:363-370.
32. Ansari RR. Ocular static and dynamic light scattering: a noninvasive diagnostic tool for eye research and clinical practice. J Biomed Opt. 2004;9:22-37.
33. Erie JC, Patel SV, McLaren JW, et al. Effect of myopic laser in situ keratomileusis on epithelial and stromal thickness: a confocal microscopy study. Ophthalmology. 2002;109:1447-1452.
34. Patel S, McLaren J, Hodge D, Bourne W. Normal human keratocyte density and corneal thickness measurement by using confocal microscopy in vivo. Invest Ophthalmol Vis Sci. 2001;42:333-339.
35. Hahnel C, Somodi S, Weiss DG, Guthoff RF. The keratocyte network of human cornea: a three-dimensional study using confocal laser scanning fluorescence microscopy. Cornea. 2000;19:185-193.
36. Li HF, Petroll WM, Møller-Pedersen T, Maurer JK, Cavanagh HD, Jester JV. Epithelial and corneal thickness measurements by in vivo confocal microscopy through focusing (CMTF). Curr Eye Res. 1997;16:214-221.
37. Mustonen RK, McDonald MB, Srivannaboon S, Tan AL, Doubrava MW, Kim CK. Normal human corneal cell populations evaluated by in vivo scanning slit confocal microscopy. Cornea. 1998;17:485-492.
38. Prydal JI, Franc F, Dilly PN, Kerr Muir MG, Corbett MC, Marshall J. Keratocyte density and size in conscious humans by digital image analysis of confocal images. Am J Optom Physiol Opt. 1998;12:337-342.
39. Petroll W, Boettcher K, Barry P, Cavanagh H, Jester J. Quantitative assessment of anteroposterior keratocyte density in the normal rabbit cornea. Cornea. 1995;14:3-9.
40. McCally RL, Farrell RA. The depth dependence of light scattering from the normal rabbit cornea. Exp Eye Res. 1976;23:69-81.
41. Farrell RA, McCally RL. On the interpretation of depth dependent light scattering measurements in normal corneas. Acta Ophthalmol (Copenh). 1976;54:261-270.
42. Efron N, Mutalib HA, Perez-Gomez I, Koh HH. Confocal microscopic observations of the human cornea following overnight contact lens wear. Clin Exp Optom. 2002;85:149-155.
43. Patel S. Refractive index of the mammalian cornea and its influence during pachometry. Ophthalmic Physiol Opt. 1987;7:503-506.
44. Patel S, Marshall J, Fitzke FW III. Refractive index of the human corneal epithelium and stroma. J Refract Surg. 1995;11:100-105.
45. Wallis NE. Recovery time course of corneal edema as determined by light scatter. J Am Optom Assoc. 1969;40:276-279.
46. Stevenson R, Vaja N, Jackson J. Corneal transparency changes resulting from osmotic stress. Ophthalmic Physiol Opt. 1983;3:33-39.
47. Kikkawa Y. Light scattering studies of the rabbit cornea. Jpn J Physiol. 1960;10:292-302.
48. Lambert S, Klyce S. The origins of Sattler's veil. Am J Ophthalmol. 1981;91:51-56.
49. Poise K, Sarver MD, Harris M. Corneal edema and vertical striae accompanying the wearing of hydrogel lenses. Am J Optom Physiol Optics. 1975;52:185-191.
50. Maurice D. The structure and transparency of the cornea. J Physiol. 1957;136:263-286.
51. Poise KA, Mandell RB. Etiology of corneal striae accompanying hydrogel lens wear. Invest Ophthalmol. 1976;15:553-556.
52. Korb DR, Exford JM. The phenomenon of central circular clouding. J Am Optom Assoc. 1968;39:223-230.
53. Fonn D, du Toit R, Simpson TL, Vega JA, Situ P, Chalmers RL. Sympathetic swelling response of the control eye to soft lenses in the other eye. Invest Ophthalmol Vis Sci. 1999;40:3116-3121.
54. Cox I, Holden BA. Can vision loss be used as a quantitative assessment of corneal edema? Int Contact Lens Clin. 1990;17:176-180.
55. O'Leary DJ, Wilson G, Henson DB. The effect of anoxia on the human corneal epithelium. Am J Optom Physiol Opt. 1981;58:472-476.
56. Johnson M, Ruben CM, Perrigin D. Entoptic phenomena and reproducibility of corneal striae following contact lens wear. Br J Ophthalmol. 1987;71:737-741.
57. Farris RL, Kubota Z, Mishima S. Epithelial decompensation with corneal contact lens wear. Arch Ophthalmol. 1971;85:651-660.
58. Lee D, Wilson G. Non-uniform swelling properties of the corneal stroma. Curr Eye Res. 1981;1:457-461.
59. Cristol SM, Edelhauser HF, Lynn MJ. A comparison of corneal stromal edema induced from the anterior or the posterior surface. Refract Corneal Surg. 1992;8:224-229.
60. Maurice D, Giardini A. Swelling of the cornea in vivo after the destruction of its limiting layers. Br J Ophthalmol. 1951;35:791-797.
61. O'Neal MR, Poise KA. In vivo assessment of mechanisms controlling corneal hydration. Invest Ophthalmol Vis Sci. 1985;26:849-856.