Lupus anticoagulants: Pathophysiology, clinical and laboratory associations: A review

East African Medical Journal

Volumn 80, Issue 11, 2003, Pages 564-568

  Mwanda, O W ^a  

^a UNIVERSITY OF NAIROBI   (Kenya)

Author keywords

[No Author keywords available]

Indexed keywords

LUPUS ANTICOAGULANT;

BLOOD; HUMAN; REVIEW; THROMBOSIS;

HUMANS; LUPUS COAGULATION INHIBITOR; THROMBOSIS;

EID: 4644351246     PISSN: 0012835X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (39)

1. Conley C.L and Hartman R.C. A haemorrhagic disorder caused by circulating anticoagulants in patients with disseminated lupus erythematosus. J. Lab. Clin. Invest. 1952; 31:621-622.
2. Feinstein D.I. and Rapaport S.I. Acquired inhibitors of blood coagulation. Prog. Haemost. Thromb. 1972; 1:75-95.
3. Bowie E.J.W., Thompson J.H., Pascuzzi C.A. and Owen C.A. Thrombosis in systemic lupus erythematosus despite circulating anticoagulants. J. Lab. Clin. Med. 1963; 662:416-430.
4. Brandt J.T., Tripplett D.A., Alving B. and Scharrer I. Criteria for the diagnosis of lupus anticoagulants: an update. On behalf of the subcommittee on lupus anticoagulants/antiphospholipids antibody of the scientific and standardization committee of the ISH. Thromb. Haem. 1995; 74:1185-1190.
5. Pierangeli S.S., Lin X.W., Barker, J.H., Anderson G. and Harris E.W. Induction of thrombosis in a mouse IgG, IgM and IgA immunoglobulins from patients with the antiphospholipid syndrome. Thromb. Haem. 1995; 45:1361-1367.
6. Gaspari, J.C., Sande J.R., Thomas C.F.J., Zighelboim, I. and Camilleri, M. Lupus anticoagulant masquerading as an acute abdomen with multiorgan involvement. Amer. J. Gastroenterol. 1995; 90:825-826 .
7. Menoussakio, H.M., Tziofas, G., Silio, M.P., et al. Higher prevalance of anticardiolipin and other autoantibodies in a healthy elderly population. Clin. Exp. Immunol. 1987; 64:5570-5576.
8. Kim C.H., Cho, Y.K., and Mok, J.E., The efficancy of immunotherapy in patients who underwent superovulation with intrauterine insemination. Fertl. Sterl. 1996; 1:33-38.
9. Cowchock, F.C, Reece, E.A, Balaban, D. et al. Repeated fetal losses associated with antiphospholipid antibodies a collaborative randomised trial comparing prednisome with low-dose heparin treatment. Amer. J. Obstet. Gynecol. 1992; 166:13-18
10. Gattorno, M., Buoncompagni, A., Molinari, A.C., et al. Antiphospholipid antibodies in paediatric system lupus erythematosus, juvenile chronic arthritis and overlap syndromes. SLE patients with both lupus anticoagulants and high-litre antibodies are at risk for clinical manifestation related to the antiphospholipid syndrome. Brit. J. Rheumatol. 1995; 34:873-871.
11. Manco-Johnson M.L. and Nuss R. Lupus anticoagulant in children with thrombosis. Amer. J. Hematol. 1995; 48:240-243.
12. Mwanda O.W. Lupus anticoagulant syndrome. A case report. East Afr. Med. J. 1998; 75:619-620.
13. Mateo, J., Oliver, A., Borell, M. et al. Laboratory evaluation and clinical characteristics of 2, 132 consecutive unselected patients with venous thromboembolism-results of the Spanish multicentric study on thrombophilia (EMET-study). Thromb. Haemost. 1997; 77:444.
14. Nimpf, F. Wurm, H. and Kostner G.M. Beta glycoprotein I (apoult) inhibitis the release reaction of human plateles during ADP induced aggregation. Atherosclerosis. 1987; 63:109-114.
15. 2 glycoprotein I is potential by a distinct subgroup of anticardiolipin antibodies. Thromb. Haemost. 1992; 68:297-300.
16. Carreras, L.O., Defreyn, G., Machin, S. J., et al. Arterial thrombosis intrauterine death and lupus anticoagualnt. Detection of immunoglobulin interfering with protacylin formation. Lancet. 1981; 1:224-246.
17. Gostriff, T.M. and Martin B.A., Low functional and high antigenic antithrombin III levels in a patient with the lupus anticoagulant thrombosis. Arthritis Rheum. 1981; 24:94-96.
18. Marciniak, E., and Rodman, E. H. Impaired ectalytic function of activated protein C. A new in vitro manifestation of lupus anticoagulant. Blood. 1989; 74:2426-2432.
19. Nilsson, T.K. and Loftvenberg, E., Decreased fibrinolytic capacity and increased Von Willebrand factor levels as indicators of endothelial cell dysfuction in patients with lupus anticoagulant. Clin. Rheum. 1989; 8:58-63.
20. Jouhikainen, T., Kekomaki, R., Leirisalo-Repo, M., Backlund, T. and Myllyla G., Platelet autoantibodies detected by immunoblotting in systemic lupus erythematosus association with lupus anticoagulant and with history of thrombosis and thrombocytopaenia. Eur. J. Haemat. 1990; 44:234-239.
21. Boey, M.L. Colaco, C.B, Gharari, A.E. and Hughes, G.R.V. Thrombosis in SLE striking association with presence of circulating lupus anticoagulant. Brit. Med. J. 1983; 287:1021-1028.
22. Alegre, V.A., Winkelmann, R.K., and Gastineau, D.A. Cutaneous thrombosis, cerebrovascular thrombosis and lupus anticoagulant- the Sneddon syndrome. Report of 10 cases. Int. J. Dermatol. 1990; 29:45-49.
23. Asherson, R.A., Thompson, R.P., Maclachlan, N., et al. Budd Chiari syndrome, visceral arterial occlusion, reccurent fetal loss and the "Lupus anticoagulant" in systemic lupus erythematosus. J. Rheumatol. 1989; 16:219-224.
24. Asherson, R.A., Harris, E.N., Gharavi, A.A., Hughes G.R.V. Reccurent stroke multi-infarct dementias and antiphospholipid antibodies. Ann. Rheuma. dis. (in press).
25. Reisin, L.H., Reisin, I., Darawshi, A. and Aviel, E., Central retinal-artery occlusion in a patient with circulating lupus anticoagulant. Ann. Ophthalmol. 1989; 21:269-271.
26. Hughes, G.R.V. Thrombosis, abortion cerebral disease and anticoagulant. Brit. Med. J. 1983; 287:1021-1023.
27. Yutani, C., Imakita, M., Ishibashi-Meda, H., et al. Pulmonary thromboembolic hypertension in systemic lupus erythematosus with lupus anticoagulant. Histopathological analysis of localization and distribution of thromboembolic in pulmonary vasculature. Intern. Med. 1995; 34:1030-1034.
28. List, A.F., and Doll, D.C., Thrombosis associated with procainamide induced lupus anticoagulant. Acta Haematol. 1989; 82:50-52.
29. Rai, R., Cohen H., Dave M., and Regan, L. Randomised controlled trial of asprin plus heparin in pregnant women with recurrent miscarriage associated with phospholipid antibodies. Brit. Med. J. 1997; 314:253-257.
30. Haywood, L. and Brown, M.D. Antiphospholipid antibodies and reccurent pregnancy loss. Clin. Obst. Gynecol. 1991; 34:1-17.
31. Jude, B., Gondemand, J., Dolle, I., et al., Lupus anticoagulant. A clinical and laboratory study of 100 cases. Clin. Lab. Haemat. 1988; 10:41-51.
32. Exner, T., Diagnosis methodologies for circulating anticoagulant. Thromb. Haemost. 1995; 741:338-344.
33. Brandt, J. T. Criteria for diagnosis of lupus anticoagulants An update. Thromb. Haemost. 1995. (in press).
34. Rivier, G., Herranz K.M.A., and Hughes, G.R.V. Thrombosis and antiphospholipid syndrome assessment of three antithrombotic treatment. Lupus. 1004; 3:85-90.
35. Dertesen, R.H.W.M. Degrout, P. G., Kater, L. and Niewenhuis, H.K., Patients with antiphospholipid antibodies and venous thrombosis should receive long term anticoagulant treatment. Ann. Rheum. Dis. 1993; 52:589-692.
36. Dostal, J., D., Rote, R.S. and Branch, D.W. IgG1 and IgG2 are the predominant subclasses of antiphospholipid antibody in women with the lupus anticoagulant. Clin. Immunol. Immunopathol. 1990; 54:309-319.
37. Cohney, S., Savige, J. and Stewart, M.R., Lupus anticoagulant in anti-neutrophil cytoplasmic antibody-associated polyarterities. Amer. J. Nephrol. 1995; 15:157-160.
38. Parke, A., The role of IVIG in the management of patients with antiphospholipid antibodies and recurrent pregnancy losses. In IVIG therapy Today. Ballow. Med. The Humana Press Inc. Totowa N. J. 1992; 105-118.
39. Piette, J.C., Preventions of recurrent thrombosis in the antiphospholipid syndrome. Lupus. 1994; 3:73-74.