Change of extracellular cAMP concentration is a sensitive reporter for bacterial fitness in high-cell-density cultures of Escherichia coli

Biotechnology and Bioengineering

Volumn 87, Issue 5, 2004, Pages 602-613

  Lin, Hongying ^a   Hoffmann, Frank ^a,b   Rozkov, Aleksei ^c   Enfors, Sven Olof ^c   Rinas, Ursula ^b   Neubauer, Peter ^a,d  

^a MARTIN LUTHER UNIVERSITY HALLE WITTENBERG   (Germany)

^b HELMHOLTZ CENTRE FOR INFECTION RESEARCH   (Germany)

^c ROYAL INSTITUTE OF TECHNOLOGY   (Sweden)

^d UNIVERSITY OF OULU   (Finland)

Author keywords

cAMP; E. coli; Fed batch cultivation; ppGpp; Recombinant protein production; RpoS

Indexed keywords

BIODEGRADATION; BIOSYNTHESIS; CELL CULTURE; GLUCOSE; GROWTH KINETICS; METABOLISM; PHYSIOLOGY;

GROWTH RATES; STARVATION;

ESCHERICHIA COLI;

ACRYLIC ACID; ALPHA GLUCOSIDASE; BASIC FIBROBLAST GROWTH FACTOR; CYCLIC AMP; GLUCOSE; GUANOSINE 3' DIPHOSPHATE 5' DIPHOSPHATE; GUANOSINE PHOSPHATE; INDOLE; RECOMBINANT PROTEIN;

ARTICLE; CELL DENSITY; DRY WEIGHT; ESCHERICHIA COLI; FED BATCH CULTURE; GROWTH RATE; NONHUMAN; NUTRIENT LIMITATION; PLASMID; PROTEIN DEGRADATION; PROTEIN SYNTHESIS; STARVATION; STRESS; TEMPERATURE DEPENDENCE;

CELL CULTURE TECHNIQUES; COLONY COUNT, MICROBIAL; CULTURE MEDIA; CYCLIC AMP; ESCHERICHIA COLI; KINETICS; PLASMIDS; RECOMBINANT PROTEINS; TIME FACTORS;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI;

EID: 4644340454     PISSN: 00063592     EISSN: None     Source Type: Journal    
DOI: 10.1002/bit.20152     Document Type: Article

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