Fever of recombinant human interferon-alpha is mediated by opioid domain interaction with opioid receptor inducing prostaglandin E 2

Journal of Neuroimmunology

Volumn 156, Issue 1-2, 2004, Pages 107-112

  Wang, Yun Xia ^a   Xu, Wei Gang ^a   Sun, Xue Jun ^a   Chen, Yi Zhang ^a   Liu, Xin Yuan ^b   Tang, Hao ^c   Jiang, Chun Lei ^a  

^a SECOND MILITARY MEDICAL UNIVERSITY   (China)

^b INSTITUTE OF BIOCHEMISTRY AND CELL BIOLOGY   (China)

^c CHINA MEDICAL UNIVERSITY   (China)

Author keywords

cAMP; Opioid domains; PGE 2; Pyrogen; Structure basis

Indexed keywords

CYCLIC AMP; LEUCINE; NALOXONE; OPIATE RECEPTOR; PROSTAGLANDIN E2; RECOMBINANT ALPHA INTERFERON; SERINE;

ANALGESIC ACTIVITY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIVIRAL ACTIVITY; ARTICLE; BRAIN SLICE; CONTROLLED STUDY; FEVER; HYPOTHALAMUS; MALE; NONHUMAN; PRIORITY JOURNAL; PROSTAGLANDIN RELEASE; PROTEIN DOMAIN; RAT;

ANIMALS; BINDING SITES; BODY TEMPERATURE; CYCLIC AMP; DINOPROSTONE; FEVER; INTERFERON TYPE I, RECOMBINANT; MALE; MUTAGENESIS, SITE-DIRECTED; PROTEIN STRUCTURE, TERTIARY; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, OPIOID; RECTUM;

EID: 4644339201     PISSN: 01655728     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jneuroim.2004.07.013     Document Type: Article

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