Method development for the quantitation of ABT-578 in rabbit artery tissue by 96-well liquid-liquid extraction and liquid chromatography/tandem mass spectrometric detection

Rapid Communications in Mass Spectrometry

Volumn 18, Issue 19, 2004, Pages 2293-2298

  Ji, Qin C ^a   Zhang, Jun ^a   Rodila, Ramona ^a   Watson, Pamela ^a   El Shourbagy, Tawakol ^a  

^a ABBOTT LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BLOOD; CALIBRATION; CONTROLLED DRUG DELIVERY; DRUG PRODUCTS; LIQUID CHROMATOGRAPHY; MASS SPECTROMETERS; MASS SPECTROMETRY; QUALITY CONTROL; TISSUE ENGINEERING;

96-WELL; ARTERY TISSUES; CONTROL SAMPLES; LC-MS-MS; LIQUID-LIQUID EXTRACTION; LIQUID-LIQUIDS; METHOD DEVELOPMENT; PERFORMANCE; TISSUE SAMPLES; WHOLE BLOOD;

TISSUE;

ABT 578; BIOMATERIAL; UNCLASSIFIED DRUG;

ANALYTIC METHOD; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERY; ARTICLE; BLOOD SAMPLING; CALIBRATION; CONTROLLED STUDY; CORRELATION COEFFICIENT; DRUG BINDING; DRUG COATING; DRUG DETERMINATION; DRUG ISOLATION; DRUG METABOLISM; DRUG TISSUE LEVEL; ELASTICITY; EVALUATION; HOMOGENATE; HOMOGENIZATION; LIQUID CHROMATOGRAPHY; LIQUID LIQUID EXTRACTION; NONHUMAN; PROCESS MONITORING; PRODUCT RECOVERY; QUANTITATIVE ASSAY; RABBIT; STENT; TANDEM MASS SPECTROMETRY; VALIDATION PROCESS;

EID: 4644335582     PISSN: 09514198     EISSN: None     Source Type: Journal    
DOI: 10.1002/rcm.1618     Document Type: Article

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