Novel transformation of 5-cyanouracil derivatives

Tetrahedron Letters

Volumn 45, Issue 43, 2004, Pages 8007-8009

  Gondela, Andrzej ^a   Gabański, Rafał ^a   Walczak, Krzysztof ^a  

^a SILESIAN UNIVERSITY OF TECHNOLOGY   (Poland)

Author keywords

1 (Dihydroxypropyl) 5 cyanouracils; Aminopropanediols; Enantiomers

Indexed keywords

1 (4 NITROPHENYL) 5 CYANO 3 METHYLURACIL; ALCOHOL DERIVATIVE; UNCLASSIFIED DRUG; URACIL DERIVATIVE;

ARTICLE; BIOTRANSFORMATION; CHEMICAL REACTION; CRYSTAL STRUCTURE; REACTION ANALYSIS; RING OPENING; SYNTHESIS; X RAY ANALYSIS;

EID: 4644333008     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tetlet.2004.09.008     Document Type: Article

References (12)

1. A. Gondela, and K. Walczak Tetrahedron Lett. 44 2003 7291 7293
2. F. Terier Nucleophilic Aromatic Displacement 1991 VCH Publishers Cambridge pp 402-424
3. P. Barczyński, and H. Van der Plas J. Org. Chem. 47 1982 1077 1079
4. K. Hirota, H. Sajiki, Y. Kitade, and Y. Maki Chem. Pharm. Bull. 37 1989 2008 2011
5. K. Hirota, Y. Kitade, H. Sajiki, and Y. Maki J. Chem. Soc., Perkin Trans. 1 1990 367 373
6. O.S. Wolfbeis Liebigs Ann. Chem. 1982 182 185
7. 13C NMR (DMSO): δ (ppm) 115.10, 117.77 (2C), 82.55, 125.12 (2C), 143.04, 145.60, 149.54, 153.93, 164.69
8. 13C NMR (DMSO): δ (ppm) 89.29, 113.99, 124.37, 128.55, 142.93, 147.23, 148.90, 153.83, 160.43
9. 13C NMR (DMSO): δ (ppm) 28.11, 88.57, 113.92, 124.39 (2C), 128.51 (2C), 143.28, 147.27, 149.29, 151.99, 159.59
10. +]
11. 3): δ (ppm) 24.95, 26.77, 28.76, 52.42, 66.24, 73.22, 89.25, 110.54, 113.23, 150.31, 151.26, 159.27
12. Crystallographic data for 4c, has been deposited with Cambridge Crystallographic Data Centre as supplementary publication number CCDC 240048. These data can be obtained free of charge via www.ccdc.cam.ac.uk/data_request/ cif, by e-mailing data_request@ccdc.cam.ac.uk, or by contacting The Cambridge Crystallographic Data Centre, 12 Union Road, Cambridge CB2 1EZ, UK; fax: +44 1223 336033