Further insight into the pathomechanism of acne by considering the 5-α-reductase inhibitory effect of linoleic acid [1]

International Journal of Dermatology

Volumn 43, Issue 9, 2004, Pages 701-

  Namazi, M R ^a  

^a SHIRAZ UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

[No Author keywords available]

Indexed keywords

BOLDENONE; GAMMA LINOLENIC ACID; ISOTRETINOIN; LINOLEIC ACID; OXYGEN; POLYUNSATURATED FATTY ACID; SEX HORMONE; STEROID 5ALPHA REDUCTASE; STEROID 5ALPHA REDUCTASE INHIBITOR; TESTOSTERONE;

ACNE; DISEASE SEVERITY; DRUG TARGETING; ENZYME ACTIVITY; HUMAN; LETTER; NEUTROPHIL; PHAGOCYTOSIS; SEBACEOUS GLAND; SEBUM SECRETION;

EID: 4644327661     PISSN: 00119059     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1365-4632.2004.02200.x     Document Type: Letter

References (4)

1. Cunliffee WJ, Simpson NB. Disorders of the sebaceous glands. In: Champion RH, Burton JL, Ebling FJG, eds Rook/Ebling/Wilkinson Textbook of Dermatology, 6th edn, vol. 3. Oxford: Blackwell Scientific Publications, 1998: 1927-1984.
2. Downing DT, Stewart ME, Wertz PW, et al. Essential fatty acids and acne. J Am Acad Dermatol 1986; 14: 221-225.
3. Akamatsu H, Komura J, Miyachi Y, et al. Suppressive effects of linoleic acid on neutrophil oxygen metabolism and phagocytosis. J Invest Dermatol 1990; 95: 271-274.
4. Chen W, Zouboulis ChC, Orfanos CE. The 5-α-reductase system and its inhibitors. Dermatology 1996; 193: 177-184.