Does a nephron deficit in rats predispose to salt-sensitive hypertension?

Kidney and Blood Pressure Research

Volumn 27, Issue 4, 2004, Pages 239-247

  Zimanyi, Monika ^a   Bertram, John F ^a   Black, M Jane ^a  

^a MONASH UNIVERSITY   (Australia)

Author keywords

Blood pressure; Glomerular volume; High salt diet; Low birth weight; Low protein diet; Nephron number; Stereology, nephron number total renal filtration surface area determination

Indexed keywords

PROTEIN; SODIUM CHLORIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BIRTH WEIGHT; CONTROLLED STUDY; FEEDING; FEMALE; GLOMERULUS FILTRATION; HYPERTENSION; LACTATION; MALE; NEPHRON; NONHUMAN; PERFUSION; PREGNANCY; PRIORITY JOURNAL; PROGENY; PROTEIN DIET; RAT; STEREOMETRY; SYSTOLIC BLOOD PRESSURE;

ANIMALS; BIRTH WEIGHT; BLOOD PRESSURE; DIET, PROTEIN-RESTRICTED; DIETARY PROTEINS; FEMALE; HYPERTENSION, RENAL; KIDNEY GLOMERULUS; LITTER SIZE; MALE; NEPHRONS; PREGNANCY; RATS; RATS, INBRED WKY; SODIUM, DIETARY; WEIGHT GAIN;

EID: 4644323324     PISSN: 14204096     EISSN: None     Source Type: Journal    
DOI: 10.1159/000079868     Document Type: Article

References (42)

1. Barker DJ, Bull AR, Osmond C, Simmonds SJ: Fetal and placental size and risk of hypertension in adult life. BMJ 1990;301:259-262.
2. Law CM, Barker DJ, Bull AR, Osmond C: Maternal and fetal influences on blood pressure. Arch Dis Child 1991;66:1291-1295.
3. Law CM, Shiell AW: Is blood pressure inversely related to birth weight? The strength of evidence from a systematic review of the literature. J Hypertens 1996;14:935-941.
4. Walker BR, McConnachie A, Noon JP, Webb DJ, Watt GC: Contribution of parental blood pressures to association between low birth weight and adult high blood pressure: Crosssectional study. BMJ 1998;316:834-837.
5. Godfrey K, Robinson S, Barker DJ, Osmond C, Cox V: Maternal nutrition in early and late pregnancy in relation to placental and fetal growth. BMJ 1996;312:410-414.
6. Goldstein RS, Hook JB, Bond JT: The effects of maternal protein deprivation on renal development and function in neonatal rats. J Nutr 1979;109:949-957.
7. Rosso P, Streeter MR: Effects of food or protein restriction on plasma volume expansion in pregnant rats. J Nutr 1979;109:1887-1892.
8. Langley SC, Jackson AA: Increased systolic blood pressure in adult rats induced by fetal exposure to maternal low protein diets. Clin Sci (Lond) 1994;86:217-222.
9. Merlet-Benichou C, Gilbert T, Muffat-Joly M, Lelièvre-Pegorier M, Leroy B: Intrauterine growth retardation leads to a permanent nephron deficit in the rat. Pediatr Nephrol 1994;8:175-180.
10. Woodall SM, Johnston BM, Breier BH, Gluckman PD: Chronic maternal undernutrition in the rat leads to delayed postnatal growth and elevated blood pressure of offspring. Pediatr Res 1996;40:438-443.
11. Tonkiss J, Trzcinska M, Galler JR, Ruiz-Opazo N, Herrera VL: Prenatal malnutrition-induced changes in blood pressure: Dissociation of stress and nonstress responses using radiotelemetry. Hypertension 1998;32:108-114.
12. Zimanyi M, Bertram JF, Black MJ: Nephron number in the offspring of rats fed a low protein diet during pregnancy. Image Anal Stereol 2000;19:219-222.
13. Vehaskari VM, Aviles DH, Manning J: Prenatal programming of adult hypertension in the rat. Kidney Int 2001;59:238-245.
14. Holemans K, Gerber R, Meurrens K, De Clerck F, Poston L, Van Assche FA: Maternal food restriction in the second half of pregnancy affects vascular function but not blood pressure of rat female offspring. Br J Nutr 1999;81:73-79.
15. Mahendran D, Donnai P, Glazier JD, D'Souza SW, Boyd RD, Sibley CP: Amino acid (system A) transporter activity in microvillous membrane vesicles from the placentas of appropriate and small for gestational age babies. Pediatr Res 1993;34:661-665.
16. Battaglia FC, Thureen PJ: Nutrition of the fetus and the premature infant. Diabetes Care 1998;21(suppl 2):B70-B74.
17. Woods LL, Ingelfinger JR, Nyengaard JR, Rasch R: Maternal protein restriction suppresses the newborn renin-angiotensin system and programs adult hypertension in rats. Pediatr Res 2001;49:460-467.
18. Benediktsson R, Lindsay RS, Noble J, Seckl JR, Edwards CR: Glucocorticoid exposure in utero: New model for adult hypertension. Lancet 1993;341:339-341.
19. Edwards CR, Benediktsson R, Lindsay RS, Seckl JR: Dysfunction of placental glucocorticoid barrier: Link between fetal environment and adult hypertension? Lancet 1993;341:355-357.
20. Hinchliffe SA, Lynch MR, Sargent PH, Howard CV, Van Velzen D: The effect of intrauterine growth retardation on the development of renal nephrons. Br J Obstet Gynaecol 1992;99:296-301.
21. Spencer J, Wang Z, Hoy W: Low birth weight and reduced renal volume in Aboriginal children. Am J Kidney Dis 2001;37:915-920.
22. Brenner BM, Garcia DL, Anderson S: Glomeruli and blood pressure: Less of one, more the other? Am J Hypertens 1988;1:335-347.
23. Nenov VD, Taal MW, Sakharova OV, Brenner BM: Multi-hit nature of chronic renal disease. Curr Opin Nephrol Hypertens 2000;9:85-97.
24. Hinchliffe SA, Sargent PH, Howard CV, Chan YF, Van Velzen D: Human intrauterine renal growth expressed in absolute number of glomeruli assessed by the disector method and Cavalieri principle. Lab Invest 1991;64:777-784.
25. Larsson L, Aperia A, Wilton P: Effect of normal development on compensatory renal growth. Kidney Int 1980;18:29-35.
26. Nyengaard JR, Bendtsen TF: Glomerular number and size in relation to age, kidney weight, and body surface in normal man. Anat Rec 1992;232:194-201.
27. Bertram JF, Johnson K, Hughson MD, Hoy WE: Renal glomerular number and size in Australian Aborigines, African Americans and white populations from the same locations: A preliminary report. Image Anal Stereol 2001;20:153-156.
28. Gilbert T, Lelièvre-Pegorier M, Malienou R, Meulemans A, Merlet-Benichou C: Effects of prenatal and postnatal exposure to gentamicin on renal differentiation in the rat. Toxicology 1987;43:301-313.
29. Pine AP, Jessop NS, Oldham JD: Maternal protein reserves and their influence on lactational performance in rats. 3. The effects of dietary protein restriction and stage of lactation on milk composition. Br J Nutr 1994;72:815-830.
30. Sampson DA, Hunsaker HA, Jansen GR: Dietary protein quality, protein quantity and food intake: Effects on lactation and on protein synthesis and tissue composition in mammary tissue and liver in rats. J Nutr 1986;116:365-375.
31. Desai M, Crowther NJ, Lucas A, Hales CN: Organ-selective growth in the offspring of protein-restricted mothers. Br J Nutr 1996;76:591-603.
32. Gundersen HJ, Jensen EB: The efficiency of systematic sampling in stereology and its prediction. J Microsc 1987;147(Pt 3):229-263.
33. Bertram JF, Soosaipillai MC, Ricardo SD, Ryan GB: Total numbers of glomeruli and individual glomerular cell types in the normal rat kidney. Cell Tissue Res 1992;270:37-45.
34. Bertram JF: Analyzing renal glomeruli with the new stereology. Int Rev Cytol 1995;161:111-172.
35. Langley-Evans SC, Nwagwu M: Impaired growth and increased glucocorticoid-sensitive enzyme activities in tissues of rat fetuses exposed to maternal low protein diets. Life Sci 1998;63:605-615.
36. Langley-Evans SC, Phillips GJ, Jackson AA: Fetal exposure to low protein maternal diet alters the susceptibility of young adult rats to sulfur dioxide-induced lung injury. J Nutr 1997;127:202-209.
37. Langley-Evans SC, Welham SJ, Jackson AA: Fetal exposure to a maternal low protein diet impairs nephrogenesis and promotes hypertension in the rat. Life Sci 1999;64:965-974.
38. Law CM, Shiell AW, Newsome CA, Syddall HE, Shinebourne EA, Fayers PM, Martyn CN, de Swiet M: Fetal, infant, and childhood growth and adult blood pressure: A longitudinal study from birth to 22 years of age. Circulation 2002;105:1088-1092.
39. Langley-Evans SC, Welham SJ, Sherman RC, Jackson AA: Weanling rats exposed to maternal low-protein diets during discrete periods of gestation exhibit differing severity of hypertension. Clin Sci (Lond) 1996;91:607-615.
40. Langley-Evans SC, Gardner DS, Jackson AA: Association of disproportionate growth of fetal rats in late gestation with raised systolic blood pressure in later life. J Reprod Fertil 1996;106:307-312.
41. Langley-Evans SC: Maternal carbenoxolone treatment lowers birthweight and induces hypertension in the offspring of rats fed a proteinreplete diet. Clin Sci (Lond) 1997;93:423-429.
42. Langley-Evans SC: Critical differences between two low protein diet protocols in the programming of hypertension in the rat. Int J Food Sci Nutr 2000;51:11-17.