Facile synthesis and initial PET imaging of novel potential heart acetylcholinesterase imaging agents [11C]pyridostigmine and its analogs

Nuclear Medicine and Biology

Volumn 31, Issue 7, 2004, Pages 957-964

  Wang, Ji Quan ^a   Miller, Michael A ^a   Fei, Xiangshu ^a   Stone, K Lee ^a   Lopshire, John C ^a   Groh, William J ^a   Zipes, Douglas P ^a   Hutchins, Gary D ^a   Zheng, Qi Huang ^a  

^a INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

11C ortho pyridostigmine; 11C para pyridostigmine; 11C pyridostigmine; Acetylcholinesterase; Heart; Positron emission tomography

Indexed keywords

ACETYLCHOLINESTERASE; PYRIDOSTIGMINE; PYRIDOSTIGMINE C 11; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLOOD; CONTROLLED STUDY; HEART; NONHUMAN; POSITRON EMISSION TOMOGRAPHY; PURIFICATION; RADIOCHEMISTRY; RAT; SOLID PHASE EXTRACTION; SYNTHESIS;

ACETYLCHOLINESTERASE; ANIMALS; CARBON RADIOISOTOPES; CHOLINESTERASE INHIBITORS; FEASIBILITY STUDIES; FEMALE; HEART; HUMANS; MALE; METABOLIC CLEARANCE RATE; MYOCARDIUM; ORGAN SPECIFICITY; POSITRON-EMISSION TOMOGRAPHY; PYRIDOSTIGMINE BROMIDE; RADIOPHARMACEUTICALS; RATS; RATS, SPRAGUE-DAWLEY; TISSUE DISTRIBUTION;

EID: 4644315261     PISSN: 09698051     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nucmedbio.2004.04.005     Document Type: Article

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