Pre-clinical studies of photodynamic therapy of intracranial tissues

Proceedings of SPIE - The International Society for Optical Engineering

Volumn 2972, Issue , 1997, Pages 64-73

  Lilge, Lothar D ^a,b   Sepers, Marja ^a   Park, Jane ^a   O'Carroll, Cindy ^a   Pournazari, Poupak ^a   Prosper, Joe ^a   Wilson, Brian C ^a,b  

^a UNIVERSITY OF TORONTO   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

Author keywords

Brain white matter; Grey matter; Photodynamic therapy; Radius of necrosis; Threshold model; Tissue uptake

Indexed keywords

BRAIN; COMPLEXATION; HISTOLOGY; IMAGE SEGMENTATION; OPTICAL MATERIALS; PHOTODYNAMIC THERAPY; PLASMONS; TIN; TISSUE; TITANIUM COMPOUNDS; TUMORS; VEGETATION;

AMINOLAEVULINIC ACIDS; BRAIN STRUCTURES; BRAIN TISSUES; CHOROID PLEXUSES; CLINICAL STUDIES; FLUENCE DISTRIBUTIONS; GREY MATTER; INTRACRANIAL TUMORS; LIGHT FLUENCE; PHOTOFRIN; PROTOPORPHYRIN IX; RABBIT MODELS; RADIUS OF NECROSIS; THRESHOLD MODEL; TISSUE NECROSIS; TREATMENT VOLUMES; VX2 TUMORS; WHITE MATTER DAMAGES;

PHOTOSENSITIZERS;

EID: 4644315167     PISSN: 0277786X     EISSN: None     Source Type: Conference Proceeding    
DOI: 10.1117/12.273488     Document Type: Conference Paper

References (22)

1. BLACK P. McL. (1991). Brain tumors, Part 1. New Eng. Med. J., 324, 1471-1476.
2. BLACK P. McL. (1991). Brian tumors, Part 2. New Eng. Med. J., 324, 1555-1564.
3. CUTLER SJ, YOUNG JL. (1975). Third national cancer survey incidence data. Nat. Cancer Inst. Monogr, 1975 , 411-454.
4. MAO et. al. (1991). Increasing cancer rates in Canada. Can. Med. Assoc. J., 145, 1583-1591.
5. HELSETH A. (1995). The incidence of primary (NS) neoplasms before and after computerized tomography. J. Neurosurgery,64, 999-1003.
6. DIRKS P, BERNSTEIN M, MULLER P, TUCHER w. (1993). Reoperation for recurrent malignant astrocytoma. Can. J. Surg, 36, 271-275.
7. KOSTRON H, PLANGGER C, FRITSCH E, MAIER H. (1990). Photodynamic treatment of malignant brain tumors. Wiener klinische Wochenzeitschrift, 102 , 531-535.
8. MULLER P, WILSON B. (1991). Photodynamic therapy of brain tumours, post-operative 'field fractionation'. J. Photochem. Photobiol., B9, 177-125.
9. KAYE AH, HILL JS. (1993). Photodynamic therapy of brain tumours. Ann. Acad. Med. Singapore, 22, 470-481.
10. LILGE L, OLIVO ML, SCHAK SW, MAGUIRE SA, PATTERSON MS, WILSON BC. (1996). The sensitivity of normal brain and intraranially implanted VX2 tumour to interstitial photodynamic therapy. Br. J. Cancer,73, 332-343.
11. MULLER PJ, WILSON BC (1993) Photodynamic therapy of brain tumours. In Photodynamic Therapy of malignancies. McCaughan J (ed)pp 201-211 RD Landes: Austin TX.
12. PATTERSON MS, WILSON BC, GRAFF R. (1990) In vivo tests of the concept of photodynamic threshold dose in normal rat liver photosensitized by aluminium chlorosulphonated phthalocyanine. Photochem. Photobiol., 51 , 343-349.
13. LILGE L, OLIVO M, SCHATZ 5, WILSON BC. (1993). Deterinination of the photodynamic threshold for normal rabbit brain and for intracranially implanted VX2 tumors. Proc. Soc. Photo-Opt. Instr. Eng., 1882, 60-72.
14. FARRELL TJ, PATTERSON MS, WILSON BC. (1992). Investigation of the dependenceof tissue necrosis on irradiation wavelength and time post injection using a photodynamic threshold dose model. In Photodynamic Therapy. Spinelli P. Dal Fante M. Marchesni R. (eds) pp 830-843. Elsevier: New York.
15. LILGE L, HAW T, WILSON BC. (1993). Miniature isotropic optical fibre probes for quantitative light dosimetry in tissue. Phys. Med. Biol., 38 , 215-230.
16. LILGE L, O'CARROLL C, WILSON BC. (1997). A solubilization technique for photosensitizer quantification in ex vivo tissue samples. J. Photochem. Photobiol. (in print).
17. WILSON BC, FIRNAU G, JEEVES WP, BROWN KI, BUONS-MCCORMICH DM. (1988). Chromatographic analysis and tissue distribution of radiocopper-labeled haematoporphyrin derivatives. Lasers Med. Sci. 3:71-80.
18. VERMA A, HIRSCH DJ, GALTT CE, RONNETT GV, SNYDER SH. (1993). Carbon monoxide, a putative neural messenger. Science, 259 , 381-384.
19. ARNFIELD MR, MATHEW RP, TULIP J, MCPHEE MS. (1992). Analysis of tissue optical coefficients using an approximate equation valid for comparable absorption and scattering. Phys. Med. Biol., 37, 1219-1230.
20. DRIVER I, LOWDEL CP, ASH DV. (1991). In vivo measurement of the optical interaction coefficients of human tumours at 630 nm. Phys. Med. Biol., 36 , 805-813.
21. LILGE L, WILSON BC. (1993). The acuracy of interstitial measurements of absolute light fluence rate in the determinationof tissue optical properties. Proc. Soc. Photo-Opt. Instr. Eng., 1882, 291-304.
22. JAcQUES 5, RODRIQUES T, SCHWARTZ, J (1995) Kinetics of ALA induced protoporphyrin IX accumulation in the liver, skin and tumor of a rat Proc. Soc. Photo-Opt. Instr. Eng., 2392 : 40-47