A randomized, placebo-controlled, crossover study of tibolone (Livial) on menopause symptoms, psychological well-being, and dyadic relationship of postmenopausal Chinese women and their spouses

Menopause

Volumn 11, Issue 4, 2004, Pages 416-422

  Lam, Po M ^a   Cheung, Grace W Y ^b   Shek, Daniel T L ^c   Lee, Dominic T S ^c   Haines, Christopher J ^c   Chung, Tony K H ^c  

^a CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

^b UNITED CHRISTIAN HOSPITAL   (Hong Kong)

^c CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

Chinese; Dyadic; Menopause; Psychological; Tibolone

Indexed keywords

PLACEBO; TIBOLONE; PREGNANE DERIVATIVE; SELECTIVE ESTROGEN RECEPTOR MODULATOR;

ADJUSTMENT; ADULT; ANXIETY; ARTICLE; BONE PAIN; BREAST DISEASE; CHINESE; CLIMACTERIUM; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; DEPRESSION; DOUBLE BLIND PROCEDURE; DYADIC ADJUSTMENT SCALE; ETHNIC GROUP; FEAR; FEMALE; GENERAL HEALTH QUESTIONNAIRE; GREENE CLIMACTERIC SCALE; HEADACHE; HEALTH STATUS; HONG KONG; HUMAN; MAJOR CLINICAL STUDY; MARRIAGE; MENOPAUSAL SYNDROME; MYALGIA; PATIENT COMPLIANCE; POSTMENOPAUSE; RANDOMIZED CONTROLLED TRIAL; RASH; RATING SCALE; SCORING SYSTEM; SIDE EFFECT; SPOUSE; TREATMENT OUTCOME; VAGINA BLEEDING; WEIGHT GAIN; WELLBEING; CHINA; DRUG EFFECT; EMOTION; HEALTH SURVEY; HUMAN RELATION; MALE; MIDDLE AGED; MULTICENTER STUDY; PHYSIOLOGY; SEXUAL BEHAVIOR; TREATMENT REFUSAL;

CHINA; CROSS-OVER STUDIES; DOUBLE-BLIND METHOD; EMOTIONS; ESTROGEN RECEPTOR MODULATORS; FEMALE; HEALTH STATUS INDICATORS; HUMANS; INTERPERSONAL RELATIONS; MALE; MIDDLE AGED; NORPREGNENES; POSTMENOPAUSE; SEXUAL BEHAVIOR; SPOUSES; TREATMENT REFUSAL;

EID: 4644310883     PISSN: 10723714     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.GME.0000109317.11228.3E     Document Type: Article

References (33)

1. Hulley S, Grady D, Bush T, et al. Randomized trial of estrogen plus progestin for secondary prevention of coronary heart disease in postmenopausal women. Heart and Estrogen/progestin Replacement Study (HERS) Research Group. Jama 1998;280:605-13.
2. Grady D, Herrington D, Bittner V, et al. Cardiovascular disease outcomes during 6.8 years of hormone therapy: Heart and Estrogen/progestin Replacement Study follow-up (HERS II). Jama 2002;288:49-57.
3. Hulley S, Furberg C, Barrett-Connor E, et al. Noncardiovascular disease outcomes during 6.8 years of hormone therapy: Heart and Estrogen/progestin Replacement Study follow-up (HERS II). Jama 2002;288:58-66.
4. Risks and benefits of estrogen plus progestin in healthy postmenopausal women: principal results From the Women's Health Initiative randomized controlled trial. Jama 2002;288:321-33.
5. Shumaker S, Legault C, Thal L, et al. Estrogen plus progestin and the incidence of dementia and mild cognitive impairment in postmenopausal women: the Women's Health Initiative Memory Study: a randomized controlled trial. JAMA 2003;289:2651-62.
6. Rapp S, Espeland M, Shumaker S, et al. Effect of estrogen plus progestin on global cognitive function in postmenopausal women: the Women's Health Initiative Memory Study: a randomized controlled trial. JAMA 2003;289:2663-72.
7. Hays J, Ockene J, Brunner R, et al. Effects of Estrogen plus Progestin on Health-Related Quality of Life. N Engl J Med 2003;348: 1839-54.
8. Kloosterboer H. Tibolone: a steroid with a tissue-specific mode of action. J Steroid Biochem Mol Biol 2001;76:231-8.
9. Davis S. Menopause: new therapies. Med J Aust. 2003;178:634-7.
10. Siseles N, Halperin H, Benencia H, et al. A comparative study of two hormone replacement therapy regimens on safety and efficacy variables. Maturitas. 1995;21:201-10.
11. Egarter C, Huber J, Leikermoser R, et al. Tibolone versus conjugated estrogens and sequential progestogen in the treatment of climacteric complaints. Maturitas.: 1996;23:55-62.
12. Laan E, van Lunsen R, Everaerd W. The effects of tibolone on vaginal blood flow, sexual desire and arousability in postmenopausal women. Climacteric 2001;4:28-41.
13. Robinson K, Foley N, Maresh S. Mood, Marriage, and Menopause. J Couns Psychol 2001;48:77-84.
14. Greene J. Constructing a standard climacteric scale. Maturitas 1998;29:25-31.
15. Shek D. Validity of the Chinese version of the General Health Questionnaire. J Clin Psychol 1989;45:890-7.
16. Goldberg D, Hillier V. A scaled version of the General Health Questionnaire. Psychol Med 1979;9:139-45.
17. Goldberg D, Gater R, Sartorius N, et al. The validity of two versions of the GHQ in the WHO study of mental illness in general health care. Psychol Med 1997;27:191-7.
18. Pan P, Goldberg D. A comparison of the validity of GHQ-12 and CHQ-12 in Chinese primary care patients in Manchester. Psychol Med 1990;20:931-40.
19. Shek D. The Chinese version of the Dyadic Adjustment Scale: does language make a difference? J Clin Psychol 1995;51:802-11.
20. Spanier G. Measuring dyadic adjustment: New scales for assessing the quality of marriage and other dyads. J Marriage Fam 1976;38: 15-28.
21. Shek D. Psychometric properties of the Chinese version of the dyadic adjustment scale. Psychologia 1994;38:7-17.
22. Lam P, Leung T, Haines C, Chung T. Climacteric symptoms and knowledge about hormone replacement therapy among Hong Kong Chinese women aged 40-60 years. Maturitas 2003;45:99-107.
23. Avis N, McKinlay S. Health-care utilization among mid-aged women. Ann N Y Acad Sci 1990;592:228-38.
24. Ballinger S. Psychosocial stress and symptoms of menopause: a comparative study of menopause clinic patients and non-patients. Maturitas 1985;7:315-27.
25. Guthrie J, Dennerstein L, Taffe J, Donnelly V. Health care-seeking for menopausal problems. Climacteric 2003;6:112-7.
26. Moore R. Livial: a review of clinical studies. Br J Obstet Gynaecol 1999;106(Suppl 19):1-21.
27. Haines C, Chung T, Leung D. A prospective study of the frequency of acute menopausal symptoms in Hong Kong Chinese women. Maturitas 1994;18:175-81.
28. Haines C, Yim S, Chung T, et al. A prospective, randomized, placebo-controlled study of the dose effect of oral oestradiol on menopausal symptoms, psychological well-being, and quality of life in postmenopausal Chinese women. Maturitas 2003;44:207-14.
29. Genazzani A, Petraglia F, Facchinetti F, et al. Effects of Org OD 14 on pituitary and peripheral beta-endorphin in castrated rats and post-menopausal women. Maturitas 1987;(Suppl 1):35-48.
30. Bosworth H, Bastian L, Kuchibhatla M, et al. Depressive symptoms, menopausal status, and climacteric symptoms in women at midlife. Psychosom Med 2001;63:603-38.
31. Hardy R, Kuh D. Change in psychological and vasomotor symptom reporting during the menopause. Soc Sci Med 2002;55:1975-88.
32. Deeks A, McCabe M. Relationship between menopausal stage and age and quality of relationships with partners, children and friends. Climacteric 1998;1:271-8.
33. Barsky A, Peekna H, Bonis J. Somatic symptom reporting in women and men. J Gen Intern Med 2001;16:266-75.