Reduced plasma membrane Ca2+-ATPase function in platelets from patients with non-insulin-dependent diabetes mellitus

Haematologica

Volumn 89, Issue 9, 2004, Pages 1142-1144

  Rosado, Juan Antonio ^a   Saavedra, Francisco Raúl ^a   Redondo, Pedro Cosme ^a   Hernández Cruz, Juan Manuel ^b   Salido, Ginés María ^a   Pariente, José Antonio ^a  

^a UNIVERSITY OF EXTREMADURA   (Spain)

^b Clinical Analysis Laboratory   (Spain)

Author keywords

Calcium release; Non insulin dependent diabetes mellitus; Platelets; PMCA; Thrombin

Indexed keywords

ADENOSINE TRIPHOSPHATASE (CALCIUM); FURA 2; GLYCOSYLATED HEMOGLOBIN; TYROSINE;

ADULT; ARTICLE; CALCIUM MOBILIZATION; CALCIUM TRANSPORT; CELL MEMBRANE; CLINICAL ARTICLE; CONTROLLED STUDY; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; ION TRANSPORT; NON INSULIN DEPENDENT DIABETES MELLITUS; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; THROMBOCYTE;

ADULT; BLOOD PLATELETS; CALCIUM; CALCIUM-TRANSPORTING ATPASES; CATION TRANSPORT PROTEINS; DIABETES MELLITUS, TYPE 2; FEMALE; HUMANS; INSULIN RESISTANCE; IONOMYCIN; MALE; PHOSPHORYLATION; PHOSPHOTYROSINE; PLASMA MEMBRANE CALCIUM-TRANSPORTING ATPASES; PLATELET ACTIVATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; THAPSIGARGIN;

EID: 4644305890     PISSN: 03906078     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (10)

1. Carr ME. Diabetes mellitus: a hypercoagulable state. J Diabetes Complications 2001;15:44-54.
2. Sobol AB, Watala C. The role of platelets in diabetes-related vascular complications. Diabetes Res Clin Pract 2000;50:1-16.
3. Rink TJ, Sage SO. Calcium signalling in human platelets. Ann Rev Physiol 1990;52:431-9.
4. 2+ homeostasis in diabetes mellitus. Am J Physiol-Heart Circ Physiol 2001;280:1480-9.
5. 2+ concentration in non-insulin-dependent diabetes mellitus. Diabetes Res 1991;18:89-94.
6. 2+ indicators with greatly improved fluorescence properties. J Biol Chem 1985;260:3440-50.
7. 2+-ATPase by small GTPase and phosphoinositides in human platelets. J Biol Chem 2000;275:19529-35.
8. Thastrup O, Dawson AP, Scharff O, Foder B, Cullen PJ, Drobak BK, et al. Thapsigargin, a novel molecular probe for studying intracellular calcium release and storage. Agents Actions 1989;27:17-23.
9. 2+-ATPase by cAMP-dependent and tyrosine phosphorylation. J Biol Chem 1997;272:15113-9.
10. Resnick LM. Ionic basis of hypertension, insulin resistance, vascular disease, and related disorders. The mechanism of "syndrome X". Am J Hypertens 1993;6:123S-34S.