Microscopy and polymerase chain reaction detection of Leishmania chagasi in the pleural and ascitic fluid of a patient with AIDS: Case report and review of diagnosis and therapy of visceral leishmaniasis

Canadian Journal of Infectious Diseases

Volumn 15, Issue 4, 2004, Pages 231-234

  Diehl, Ada R S ^a   Dos Santos, Rodrigo P ^a   Zimmerman, Ricardo ^a   Luz, Letícia P ^a   Weiss, Tanara ^a   Jacobson, Pedro ^a   Goldani, Luciano Z ^a,b  

^a HOSPITAL DE CLÍNICAS DE PORTO ALEGRE   (Brazil)

^b CAPE COD HOSPITAL   (United States)

Author keywords

Diagnosis; HIV; Leishmania; PCR; Polymerase chain reaction; Treatment

Indexed keywords

ALLOPURINOL; AMPHOTERICIN B; AMPHOTERICIN B LIPID COMPLEX; ANTIRETROVIRUS AGENT; FLUCONAZOLE; INTERFERON; ITRACONAZOLE; KETOCONAZOLE; LIVER ENZYME; MEGLUMINE ANTIMONATE; METRONIDAZOLE; MILTEFOSINE; PENTAVALENT ANTIMONY; STIBOGLUCONATE SODIUM; TERBINAFINE; UNCLASSIFIED DRUG;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; ADJUVANT THERAPY; AMASTIGOTE; ASCITES FLUID; BRAZIL; CASE REPORT; CLINICAL FEATURE; COMPUTER ASSISTED TOMOGRAPHY; DIAGNOSTIC ACCURACY; DIAGNOSTIC TEST; ECG ABNORMALITY; ENDEMIC DISEASE; FATIGUE; HIGHLY ACTIVE ANTIRETROVIRAL THERAPY; HUMAN; IMMUNE DEFICIENCY; INTERMETHOD COMPARISON; LEISHMANIA CHAGASI; LEISHMANIASIS; LIVER TOXICITY; LUNG LAVAGE; MACROPHAGE; MICROSCOPY; MYALGIA; NON INVASIVE MEASUREMENT; OPPORTUNISTIC INFECTION; PANCREATITIS; PLEURA BIOPSY; PLEURA EFFUSION; PLEURA FLUID; POLYMERASE CHAIN REACTION; REVIEW; SENSITIVITY AND SPECIFICITY; SHORT COURSE THERAPY; THORAX RADIOGRAPHY; VISCERAL LEISHMANIASIS;

EID: 4644297514     PISSN: 11802332     EISSN: None     Source Type: Journal    
DOI: 10.1155/2004/680153     Document Type: Review

References (26)

1. Berman JD. Human leishmaniasis: Clinical, diagnostic and chemotherapeutic developments in the last 10 years. Clin Infect Dis 1997;24:684-703.
2. Pearson RD, Souza AQ. Clinical spectrum of leishmaniasis. Clin Infect Dis 1996;22:1-13.
3. Alvar J, Canavate C, Gutierrez-Solar B, et al. Leishmania and human immunodeficiency virus coinfection: The first 10 years. Clin Microbiol Rev 1997;10:298-319.
4. Duarte MI, da Matta VL, Corbett CE, Laurenti MD, Chebabo R, Goto H. Interstitial pneumonitis in human visceral leishmaniasis. Trans R Soc Trop Med Hyg 1989;83:73-6.
5. Chenoweth CE, Singal S, Pearson RD, Betts RF, Markovitz DM. Acquired immunodeficiency syndrome-related visceral leishmaniasis presenting in a pleural effusion. Chest 1993;103:648-9.
6. Munoz-Rodriguez FJ, Padro S, Pastor P, et al. Pleural and peritoneal leishmaniasis in an AIDS patient. Eur J Clin Microbiol Infect Dis 1997;16:246-8.
7. Casado JL, Cuesta C, Sanchez JA, Guerrero A. Solitary pulmonary nodule due to Leishmania in a patient with AIDS. Clin Infect Dis 1998;26:532-3.
8. Romeu J, Srera G, Carreres A, Condom MJ, Clotet B. Visceral leishmaniasis involving the lung and a cutaneous Kaposi's sarcoma lesion. AIDS 1991,5:172.
9. Matheron S, Cable A, Parquin F, et al. Visceral leishmaniasis and HIV infection: Unusual presentation with pleuropulmonary involvement, and effects of secondary prophylaxis. AIDS 1992;6:238-40.
10. Barker DC, Gibson LJ, Kennedy WP, Nasser AA, Williams RH. The potential of using recombinant DNA species-specific probes for the identification of tropical Leishmania. Parasitology 1986;92(Suppl):S139-74.
11. Cruz I, Canavate C, Rubio JM, et al. A nested polymerase chain reaction (Ln-PCR) for diagnosing and monitoring Leishmania infantum infection in patients co-infected with immunodeficiency virus. Trans R Soc Trop Med Hyg 2002;96(Suppl 1):S185-9.
12. Badaró R, Jones TC, Loreņo R, et al. A prospective study of visceral leishmaniasis in an endemic area of Brazil. J Infect Dis 1986;154:639-49.
13. Pintado V, López-Vélez R. HIV-associated visceral leishmaniasis. Clin Microbiol Infect 2001;7:291-300.
14. Pintado V, Martín-Rabadán P, Rivera ML, Moreno S, Bouza E. Visceral leishmaniasis in human immunodeficiency virus (HIV)-infected and non-HIV-infected patients: A comparative study. Medicine 2001;80:54-73.
15. Lopez-Velez R, Laguna F, Alvar J, et al. Parasitic culture of buffy coat for diagnosis of visceral leishmaniasis in human immunodeficiency virus-infected patients. J Clin Microbiol 1995;33:937-9.
16. Mary C, Lamouroux D, Dunan S, Quiilici M. Western blot analysis of antibodies to Leishmania infantum antigens: Potential of the 14-kD and 16-kD antigens for diagnosis and epidemiological purposes. Am J Trop Med Hyg 1992;47:764-71.
17. Kar K. Serological diagnosis of leishmaniasis. Crit Rev Microbiol 1995;21:123-52.
18. da Costa CA, de Toledo VP, enaro O, Williams P, Mayrink W. Montenegro skin test: Evaluation of the composition and stability of the antigen preparation. Mem Inst Oswaldo Cruz 1996;91:193-4.
19. Herwaldt BL, Berman JD. Recommendations for treating leishmaniaisis with sodium stibogluconate (Pentostam) and review of pertinent clinical studies. Am J Trop Med Hyg 1992;46:296-306.
20. Sundar S, Singh VP, Sharma S, Makharia MK, Murray HW. Response to interferon-gamma plus pentavalent antimony in Indian visceral leishmaniasis. J Infect Dis 1997;176:1117-9.
21. Murray HW. Treatment of visceral leishmaniasis (kala-azar): A decade of progress and future approaches. Int J Infect Dis 2000;4:158-77.
22. Sundar S, Jha TK, Thakur CP, et al. Oral miltefosine for Indian visceral leishmaniasis. N Engl J Med 2002;347:1739-46.
23. Mishra M, Biswas UK, Jha Am, Khan AB. Amphotericin versus sodium stibogluconate in first-line treatment of Indian kala-azar. Lancet 1994;344:1599-600.
24. Sundar S, Agrawall G, Rai M, Makharia MK, Murray HW. Treatment of Indian visceral leishmaniasis with single or daily infusions of low dose liposomal amphotericin B: Randomized trial. BMJ 2001;323:419-22.
25. Lafeuillade A, Chaffanjon P, Delbeke E, Quilichini R. Maintenance itraconazole for visceral leishmaniasis in HIV infection. Am J Med 1992;92:449.
26. Berenguer J, Cosin J, Miralles P, Lopez JC, Padilla B. Discontinuation of secondary anti-Leishmania prophylaxis in HIV-infected patients which have responded to highly active antiretroviral therapy. AIDS 2000;14:2946-8.