Circulating malondialdehyde modified LDL is a biochemical risk marker for coronary artery disease

Heart

Volumn 90, Issue 10, 2004, Pages 1211-1213

  Amaki, T ^a   Suzuki, T ^a   Nakamura, F ^a   Hayashi, D ^a   Imai, Y ^a   Morita, H ^a   Fukino, K ^a   Nojiri, T ^a   Kitano, S ^b   Hibi, N ^b   Yamazaki, T ^a   Nagai, R ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b SRL INC   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

APOLIPOPROTEIN B; BIOCHEMICAL MARKER; HIGH DENSITY LIPOPROTEIN; LOW DENSITY LIPOPROTEIN; MALONALDEHYDE; MALONDIALDEHYDE MODIFIED LOW DENSITY LIPOPROTEIN; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

ADULT; AEROBIC METABOLISM; AGED; ARTICLE; CARDIOVASCULAR RISK; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; CORONARY ARTERY DISEASE; DIAGNOSTIC ACCURACY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMAN; INTERMETHOD COMPARISON; LIPID OXIDATION; LIPOPROTEIN BLOOD LEVEL; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL;

AGED; BIOLOGICAL MARKERS; CASE-CONTROL STUDIES; CHOLESTEROL, LDL; CORONARY DISEASE; FEMALE; HUMANS; MALE; MALONDIALDEHYDE; MIDDLE AGED; ROC CURVE;

EID: 4644296327     PISSN: 13556037     EISSN: None     Source Type: Journal    
DOI: 10.1136/hrt.2003.018226     Document Type: Article

References (5)

1. Steinberg D, Parthasarathy S, Carew TE, et al. Beyond cholesterol. Modifications of low-density lipoprotein that increase its atherogenicity. N Engl J Med 1989;320:915-24.
2. Ross R. The pathogenesis of atherosclerosis: a perspective for the 1990s. Nature 1993;362:801-9.
3. Haberland ME, Fong D, Cheng L. Malondialdehyde-altered protein occurs in atheroma of Watanabe heritable hyperlipidemic rabbits. Science 1988;241:215-8.
4. Fogelman AM, Shechter I, Seager J, et al. Malondialdehyde alteration of low density lipoproteins leads to cholesteryl ester accumulation in human monocyte-macrophages. Proc Natl Acad Sci U S A 1980;77:2214-8.
5. Kotani K, Maekawa M, Kanno T, et al. Distribution of immunoreactive malondialdehyde-modified low-density lipoprotein in human serum. Biochim Biophys Acta 1994;1215:121-5.