Increased insulin receptor substrate 1 serine phosphorylation and stress-activated protein kinase/c-Jun N-terminal kinase activation associated with vascular insulin resistance in spontaneously hypertensive rats

Hypertension

Volumn 44, Issue 4, 2004, Pages 484-489

  Sugita, Michiko ^a   Sugita, Hiroki ^a   Kaneki, Masao ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

Aorta; Insulin resistance; Kinase; Phosphorylation; Rats, spontaneously hypertensive; Signal transduction

Indexed keywords

INSULIN; INSULIN RECEPTOR; INSULIN RECEPTOR SUBSTRATE 1; PHOSPHATIDYLINOSITOL 3 KINASE; SERINE; STRESS ACTIVATED PROTEIN KINASE; TYROSINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AORTA; ARTICLE; CELL STRAIN COS7; CONTROLLED STUDY; DISEASE ASSOCIATION; ENZYME ACTIVATION; ENZYME ACTIVITY; IMMUNOBLOTTING; IMMUNOPRECIPITATION; IN VITRO STUDY; INSULIN RESISTANCE; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RAT; RAT STRAIN; SIGNAL TRANSDUCTION; SPONTANEOUSLY HYPERTENSIVE RAT;

ANIMALS; AORTA; INSULIN RESISTANCE; MALE; MITOGEN-ACTIVATED PROTEIN KINASE 8; PHOSPHOPROTEINS; PHOSPHORYLATION; RATS; RATS, INBRED SHR; RATS, INBRED WKY; SIGNAL TRANSDUCTION;

EID: 4644287668     PISSN: 0194911X     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.HYP.0000140778.53811.20     Document Type: Article

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