Antistaphylococcal activity of CB-181963 (CAB-175), an experimental parenteral cephalosporin

Antimicrobial Agents and Chemotherapy

Volumn 48, Issue 10, 2004, Pages 4037-4039

  Hoellman, Dianne B ^a   Pankuch, Glenn A ^a   Appelbaum, Peter C ^a  

^a PENN STATE MILTON S HERSHEY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC AGENT; CAB 175; CB 181963; CD 181963; CEPHALOSPORIN DERIVATIVE; DALFOPRISTIN PLUS QUINUPRISTIN; LEVOFLOXACIN; LINEZOLID; RANBEZOLID; TEICOPLANIN; TIGECYCLINE; UNCLASSIFIED DRUG; VANCOMYCIN;

ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIAL STRAIN; BACTERICIDAL ACTIVITY; BACTERIOSTASIS; CONTROLLED STUDY; DOSE TIME EFFECT RELATION; GENE ISOLATION; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PRIORITY JOURNAL; STAPHYLOCOCCUS AUREUS; STRAIN DIFFERENCE;

ANTI-BACTERIAL AGENTS; CEPHALOSPORINS; COLONY COUNT, MICROBIAL; KINETICS; METHICILLIN RESISTANCE; STAPHYLOCOCCUS AUREUS; VANCOMYCIN RESISTANCE;

EID: 4644282173     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/AAC.48.10.4037-4039.2004     Document Type: Article

References (18)

1. Blumberg, H. M., D. Rimland, D. J. Carroll, P. Terry, and I. K. Wachsmuth. 1991. Rapid development of ciprofloxacin resistance in methicillin-susceptible and -resistant Staphylococcus aureus. J. Infect. Dis. 163:1279-1285.
2. Bozdogan, B., D. Esel, C. Whitener, F. A. Browne, and P. C. Appelbaum. 2003. Antibacterial susceptibility of a vancomycin-resistant Staphylococcus aureus isolated at Hershey Medical Center. J. Antimicrob. Chemother. 52: 864-868.
3. Cercenado, E., F. Garcia-Garrote, and E. Bouza, E. 2001. In-vitro activity of linezolid against multiply resistant gram-positive clinical isolates. J. Antimicrob. Chemother. 47:77-81.
4. Cuny, C., and W. Witte. 2000. In vitro activity of linezolid against staphylococci. Clin. Microbiol. Infect. 6:328-333.
5. Diekema, D. J., and R. N. Jones. 2000. Oxazolidinones. A review. Drugs 59:7-16.
6. Henwood, C. J., D. M. Livermore, A. P. Johnson, D. James, M. Warner, A. Gardiner, and the Linezolid Study Group. 2000. Susceptibility of gram-positive cocci from 25 UK hospitals to antimicrobial agents including linezolid. J. Antimicrob. Chemother. 46:931-940.
7. Hershow, R. C., W. F. Khayr, and P. C. Schreckenherger. 1998. Ciprofloxacin resistance in methicillin-resistant Staphylococcus aureus: associated factors and resistance to other antibiotics. Antimicrob. Agents Chemother. 5:213-220.
8. Hiramatsu, K. 1998. The emergence of Staphylococcus aureus with reduced susceptibility to vancomycin in Japan. Am. J. Med. 104:7S-10S.
9. Hoellman, D., G. Lin, L. M. Ednie, A. Rattan, M. R. Jacobs, and P. C. Appelbaum. 2003. Antipneumococcal and antistaphylococcal activities of ranbezolid (RBX 7644), a new oxazolidinone, compared to those of other agents. Antimicrob. Agents Chemother. 47:1148-1150.
10. Linde, H. J., M. Schmidt, E. Fuchs, U. Reischl, H. H. Niller, and N. Lehn. 2001. In vitro activities of six quinolones and mechanisms of resistance in Staphylococcus aureus and coagulase-negative staphylococci. Antimicrob Agents Chemother. 45:1553-1557.
11. Livermore, D. M. 2000. Quinupristin/dalfopristin and linezolid: where, when, which and whether to use? J. Antimicrob. Chemother. 46:347-350.
12. National Committee for Clinical Laboratory Standards. 2000. Methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobically-fifth edition; approved standard. NCCLS publication no. M7-A5. National Committee for Clinical Laboratory Standards, Wayne, Pa.
13. Nichols, R. L. 1999. Optimal treatment of complicated skin and soft tissue infections. J. Antimicrob. Chemother. 44:19-23.
14. Pankuch, G. A., M. R. Jacobs, and P. C. Appelbaum. 2003. Bactericidal activity of daptomycin against Streptococcus pneumoniae compared with eight other antimicrobials. J. Antimicrob. Chemother. 51:443-446.
15. Schmitz, F.-J., A. Fluit, S. Brisse, J. Verhoef, K. Koher, and D. Milatovic. 1999. Molecular epidemiology of quinolone resistance and comparative in vitro activities of new quinolones against European Staphylococcus aureus isolates. FEMS Immunol. Med. Microbiol. 26:281-287.
16. Stevens, D. L., L. G. Smith, J. B. Bruss, M. A. McConnell-Martin, S. E. Duvall, W. M. Todd, and B. Hafkin. 2000. Randomized comparison of linezolid (PNU-100766) versus oxacillin-dicloxacillin for treatment of complicated skin and soft tissue infections. Antimicrob. Agents Chemother. 44:3408-3413.
17. Tenover, F. C., L. M. Weigel, P. C. Appelbaum, L. K. McDougal, J. Chaitram, S. McAllister, N. Clark, G. Killgore, C. M. O'Hara, L. Jevitt, J. B. Patel, and B. Bozdogan. 2004. Vancomycin-resistant Staphylococcus aureus isolate from a patient in Pennsylvania. Antimicrob. Agents Chemother. 48:275-280.
18. Voss, A., D. Milatovic, C. Wallrauch-Schwarz, V. T. Rosdahl, and I. Braveny. 1994. Methicillin-resistant Staphylococcus aureus in Europe. Eur. J. Clin. Microbiol. Infect. Dis. 13:50-55.